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The combined administration of synthetic human EGF\/URO and cimetidine further increased healing of gastric ulcers compared with administration of each substance. Neither synthetic human EGF\/URO, nor removal of the submandibular glands had any influence on gastric acid secretion. This study showed that the submandibular glands influence healing of chronic gastric ulcers and suggest that EGF\/URO participate in healing of chronic gastric ulcers in rats.<\/jats:p>","DOI":"10.1136\/gut.27.12.1443","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1443-1449","source":"Crossref","is-referenced-by-count":122,"title":["Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats."],"prefix":"10.1136","volume":"27","author":[{"given":"P S","family":"Olsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S","family":"Poulsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Therkelsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Nex\u00f8","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1146\/annurev.me.33.020182.001151","article-title":"Pathogenesis ot gastric mucosal injury","volume":"33","author":"Guth, P.H.","year":"1982","unstructured":"Guth PH. 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