{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T02:57:29Z","timestamp":1770433049601,"version":"3.49.0"},"reference-count":5,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1986,12]]},"abstract":"<jats:p>Sixty two patients with a clinical suspicion of biliary dyskinesia were investigated with endoscopic manometry of the sphincter of Oddi before and after intravenous injection of cholecystokinin or ceruletide. In 52 patients injection was followed by decreased pressure in the sphincter of Oddi; 43 of these had normal prestimulatory values (group I), while the values were raised in the other nine patients (group II). A paradoxical response to intravenous injection was observed in 10 women (group III): increased baseline sphincteric pressure occurred in eight and increase in the amplitude of phasic contractions in four patients. The prestimulatory sphincteric pressure was raised in five and normal in the remaining patients. Eight patients were treated with papillotomy (seven) or balloon dilatation of the sphincter (one). They experienced relief of pain during a follow up period of 11-16 months. Intravenous injection of cholecystokinin or ceruletide may disclose a special type of biliary dyskinesia even in patients with normal prestimulatory manometric findings. Hormone injection increases the diagnostic yield of endoscopic manometry in patients suspected of biliary dyskinesia.<\/jats:p>","DOI":"10.1136\/gut.27.12.1507","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1507-1511","source":"Crossref","is-referenced-by-count":50,"title":["Paradoxical response of sphincter of Oddi to intravenous injection of cholecystokinin or ceruletide. Manometric findings and results of treatment in biliary dyskinesia."],"prefix":"10.1136","volume":"27","author":[{"given":"P","family":"Rolny","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Arleb\u00e4ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Funch-Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Kruse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ravnsbaeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"J\u00e4rnerot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,12,1]]},"reference":[{"key":"ref_1","first-page":"1085","article-title":"Paradoxical motof response to cholecystokinin sphincter of Oddi pressure could be an artefact-for (CCK-OP) in patients with suspected sphincter of Oddi example, pain which often accompanied the hordysfunction","volume":"82","author":"W, Hogan W.Geenen J.Dodds; J, Toouli; R, Venu; J, Helm","year":"1982","unstructured":"Hogan W. Geenen J. Dodds W, Toouli J, Venu R, Helm J. Paradoxical motof response to cholecystokinin sphincter of Oddi pressure could be an artefact-for (CCK-OP) in patients with suspected sphincter of Oddi example, pain which often accompanied the hordysfunction. Gastroenterology 1982; 82: 1085.","journal-title":"Gastroenterology"},{"key":"ref_2","first-page":"239","article-title":"Caerulein and sphincter of Oddi pressure activity","volume":"14","author":"Corazziairi, E.; DeMasi, E.; Gatti, V.","year":"1982","unstructured":"Corazziairi E, DeMasi E, Gatti V et al. Caerulein and sphincter of Oddi pressure activity. Ital J Gastroenterol 1982; 14: 239-41.","journal-title":"Ital J Gastroenterol"},{"key":"ref_3","first-page":"169","article-title":"Caerulein (ceruletide). A review","volume":"39","author":"Ganzinai, F.; Santamaria, A.","year":"1976","unstructured":"Ganzinai F, Santamaria A. Caerulein (ceruletide). A review. Acta Gastroenterol Belg 1976; 39: 169-85.","journal-title":"Acta Gastroenterol Belg"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/S0016-5085(85)80086-X","article-title":"Manometric disorders in patients with suspected sphincter of Oddi dysfunction","volume":"88","author":"Toouli, J.; Dcnt, Roberts-Thomsom I.C.; J, Lee; J.","year":"1985","unstructured":"Toouli J, Roberts-Thomsom IC. Dcnt J, Lee J. Manometric disorders in patients with suspected sphincter of Oddi dysfunction. Gastroentierology 1985; 88: 1243-50.","journal-title":"Gastroentierology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/bjs.1800710402","article-title":"Sphincter of Oddi motility","volume":"71","author":"Toouli, J.","year":"1984","unstructured":"Toouli J. Sphincter of Oddi motility. Br J Surg 1984; 71: 251-56.","journal-title":"Br J Surg"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.27.12.1507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T13:37:31Z","timestamp":1765633051000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.27.12.1507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,12]]},"references-count":5,"journal-issue":{"issue":"12","published-online":{"date-parts":[[1986,12,1]]},"published-print":{"date-parts":[[1986,12]]}},"alternative-id":["10.1136\/gut.27.12.1507"],"URL":"https:\/\/doi.org\/10.1136\/gut.27.12.1507","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,12]]}}}