{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T22:59:34Z","timestamp":1765666774014,"version":"3.48.0"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>The effect of cisapride, a new gastrointestinal prokinetic agent, on the transit of a standard meal through the stomach, small intestine and colon was studied in 10 normal subjects. Cisapride had no significant effect on gastric emptying but decreased mouth to caecum transit time (p less than 0.01). Stool weight and frequency were not significantly increased but the time for the first appearance of stool markers and the arrival of 20% and 50% of stool markers was decreased after cisapride (p less than 0.05).<\/jats:p>","DOI":"10.1136\/gut.28.1.13","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"13-16","source":"Crossref","is-referenced-by-count":85,"title":["Effect of cisapride on the gastrointestinal transit of a solid meal in normal human subjects."],"prefix":"10.1136","volume":"28","author":[{"given":"C A","family":"Edwards","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Holden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N W","family":"Read","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1987,1,1]]},"reference":[{"key":"ref_1","first-page":"1045","article-title":"Clinicill pharmacologicail cvidcnce for cisiapride's lack of atntidopaminergic or direct cholinergic properties","volume":"36","author":"A, I.Reyntjens; M, Verlinden; R, Dc Coster; ei al","year":"1984","unstructured":"I Reyntjens A, Verlinden M, Dc Coster R, ei al. Clinicill pharmacologicail cvidcnce for cisiapride's lack of atntidopaminergic or direct cholinergic properties. Curr Ther Res 1984; 36: 1045-52.","journal-title":"Curr Ther Res"},{"key":"ref_2","first-page":"1157","article-title":"Ettect of cisapride on the motility of gut in dogs and colonic transit time in dogs aind humans. (Gasiroenterolog)'","volume":"86","author":"Lee, K.Y.; Chey, W.Y.; You, C.H.; Shah, A.N.; Hamilton, D.","year":"1984","unstructured":"Lee KY, Chey WY, You CH, Shah AN, Hamilton D. Ettect of cisapride on the motility of gut in dogs and colonic transit time in dogs aind humans. (Gasiroenterolog)' 1984; 86: 1157."},{"key":"ref_3","first-page":"1271","article-title":"Characteristic motor stimulating effect of cisapride on gastrointestinal tract in conscious dogs","volume":"86","author":"Suzuki, T.; Niakiayia, M.; Arai, H.; Itoh, Wakahayashi K.; Z.","year":"1984","unstructured":"Suzuki T, Niakiayia M, Arai H, Wakahayashi K. Itoh Z. Characteristic motor stimulating effect of cisapride on gastrointestinal tract in conscious dogs. Gastroenierology 1984; 86: 1271.","journal-title":"Gastroenierology"},{"key":"ref_4","first-page":"18","article-title":"Prokinetic effects of cisapride on normal and reduced antroduodenal motility and reflexes","volume":"36","author":"Rehoa, G.; Arnulfo, G.; di Sommra, C.; ei al","year":"1984","unstructured":"Rehoa G, Arnulfo G, di Sommra C, ei al. Prokinetic effects of cisapride on normal and reduced antroduodenal motility and reflexes. Ctirr Tlier Res 1984; 36: 18-23.","journal-title":"Ctirr Tlier Res"},{"key":"ref_5","first-page":"1276","article-title":"Transit of a meal through the stomach, small intestine aind colon in normal subjects and its role","volume-title":"the pathogenesis of diarrhoea. Gastroenterology 1980; 79","author":"Read, N.W.; Miles, C.A.; Fisher, D.","unstructured":"Read NW, Miles CA, Fisher D, et al. Transit of a meal through the stomach, small intestine aind colon in normal subjects and its role in the pathogenesis of diarrhoea. Gastroenterology 1980; 79: 1276-82."},{"key":"ref_6","first-page":"1","article-title":"Routine radiological follow-through examination shows effect of cisapride on gastrointestinal transit: a controlled study","volume":"36","author":"L, Van Daele; A, De Cuypere; M, Van Kerckhove","year":"1984","unstructured":"Van Daele L, De Cuypere A, Van Kerckhove M. Routine radiological follow-through examination shows effect of cisapride on gastrointestinal transit: a controlled study. Curr Ther Res 1984; 36: 1t)38-44.","journal-title":"Curr Ther Res"},{"key":"ref_7","first-page":"1307","article-title":"Effects of cisapride on gastric emptying of solids in dyspeptic patients","volume":"25","author":"Corinaldesi, R.; Zarabini, Stanghellini V.; G.E.","year":"1984","unstructured":"Corinaldesi R, Stanghellini V. Zarabini GE. et al. Effects of cisapride on gastric emptying of solids in dyspeptic patients. [Abstracti. Gut 1984; 25: A1307.","journal-title":"[Abstracti. Gut"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1136\/gut.26.4.352","article-title":"Measurement of gastric emptying in dyspeptic patients: effect of a new gastrokinetic agent (cisapride)","volume":"26","author":"Jian, R.; Ducrot, F.; Piedeloup, C.; Mary, J.Y.; Najean, Y.; Bernier, J.J.","year":"1985","unstructured":"Jian R, Ducrot F, Piedeloup C, Mary JY, Najean Y, Bernier JJ. Measurement of gastric emptying in dyspeptic patients: effect of a new gastrokinetic agent (cisapride). Gut 1985; 26: 352-8.","journal-title":"Gut"},{"issue":"25","key":"ref_9","first-page":"1310","article-title":"Cisapride stimulates peristaltic activity of the canine jejunum during the digestive period","volume":"1984","author":"Schemann, M.; Ehrlein, H.J.","unstructured":"Schemann M, Ehrlein HJ. Cisapride stimulates peristaltic activity of the canine jejunum during the digestive period. [Abstract]. Gut 1984: 25: A1310.","journal-title":"Gut"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1007\/BF01296904","article-title":"Holgate AM, Read NW. Relationship between small bowel transit time and absorption of a solid meal. Influence of metoclopramide. magnesium sulphate and lactulose","volume":"28","year":"1983","unstructured":"Holgate AM, Read NW. Relationship between small bowel transit time and absorption of a solid meal. Influence of metoclopramide. magnesium sulphate and lactulose. Dig Dis Sci 1983; 28: 812-9.","journal-title":"Dig Dis Sci"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/S0016-5085(76)80143-6","article-title":"Intraluminal pressures during perfusion of the human colon in situ","volume":"70","author":"Chauve, A.; Devroede, G.; Bastin, E.","year":"1976","unstructured":"Chauve A, Devroede G, Bastin E. Intraluminal pressures during perfusion of the human colon in situ. Gastroeniterology 1976; 70: 336-40.","journal-title":"Gastroeniterology"},{"key":"ref_12","first-page":"1135","article-title":"Oral domperidone: double blind comparison with placebo in irritable bowel syndrome","volume":"24","author":"Cann PA, Read NW, Holdsworth CD","year":"1983","unstructured":"Cann PA, Read NW, Holdsworth CD. Oral domperidone: double blind comparison with placebo in irritable bowel syndrome. Glut 1983: 24: 1135-40.","journal-title":"Glut"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.28.1.13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T12:09:56Z","timestamp":1765627796000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.28.1.13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1987,1,1]]},"published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.1136\/gut.28.1.13"],"URL":"https:\/\/doi.org\/10.1136\/gut.28.1.13","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1987,1]]}}}