{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:39:20Z","timestamp":1790195960504,"version":"4.1.0"},"reference-count":34,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1987,10]]},"abstract":"<jats:p>Utilising the population based data resources of the Rochester Epidemiology Project, we estimated survival and risk of subsequent colon cancer in the 182 residents of Rochester, Minnesota, initially diagnosed with chronic ulcerative colitis (CUC) between 1985 and 1979. Twenty five (13.7%) had a proctocolectomy during the course of follow up. Three patients developed colorectal adenocarcinoma after the initial diagnosis of CUC (relative risk = 1.9, 95% CI 0.4-5.4). Excluding proctitis cases, the relative risk of cancer was 2.4 (95% CI 0.3-8.7). At last follow up, 37 (20.3%) were dead; only 10 patients had chronic ulcerative colitis mentioned on the death certificate. Overall survival was similar to that expected for the general population of like age and sex. Our results suggest that chronic ulcerative colitis in the community is typically a milder disease than would appear from hospital or referral centre series.<\/jats:p>","DOI":"10.1136\/gut.28.10.1261","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1261-1266","source":"Crossref","is-referenced-by-count":80,"title":["Prognosis of chronic ulcerative colitis in a community."],"prefix":"10.1136","volume":"28","author":[{"given":"C M","family":"Stonnington","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S F","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A R","family":"Zinsmeister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"3rd","given":"L J","family":"Melton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1987,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/S0016-5085(19)30527-X","article-title":"Cancer risk in ulcerative colitis: scientific requirements for the study of prognosis","volume":"78","author":"Sackett, D.L.; Whclan, G.","year":"1980","unstructured":"Sackett DL, Whclan G. 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CGastroenterology 1983; 85: 1-1 1."},{"key":"ref_9","first-page":"158","article-title":"Long term prognosis in ulcerative colitis - based on results from a regional patient group from the county of Copenhagen","volume":"26","author":"S, Hendriksen C.Kreiner; V, Binder","year":"1985","unstructured":"Hendriksen C. Kreiner S, Binder V. Long term prognosis in ulcerative colitis - based on results from a regional patient group from the county of Copenhagen. Ciii 1985; 26: 158-63.","journal-title":"Ciii"},{"key":"ref_10","article-title":"An audit of ulccrative colitis in a district gcneral hospital [Abstract]. CGu 1985; 26: A 1123","author":"Jones, H.W.; Grogono, J.; Hoare, A.M.","unstructured":"Jones HW, Grogono J, Hoare AM. An audit of ulccrative colitis in a district gcneral hospital [Abstract]. 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A study of ulcerative colitis in New Zealand, showing a low incidence in Maoris. Br Med J 1962; ii: 228-31.","journal-title":"Br Med J"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0016-5085(63)80111-0","article-title":"Ulcerative colitis in United States Army in 1944. Epidemiology: Comparisons between patients-and controls","volume":"44","year":"1963","unstructured":"Acheson ED, Nefzgcr MD. Ulcerative colitis in United States Army in 1944. Epidemiology: Comparisons between patients-and controls. Castroenterology 1963; 44: 7-19.","journal-title":"Castroenterology"},{"key":"ref_15","first-page":"15","article-title":"The course and prognosis of ulcerative colitis. Part IV. Carcinoma of the colon","volume":"5","author":"SC, Edwards F.C.Truelove","year":"1964","unstructured":"Edwards FC. Truelove SC. The course and prognosis of ulcerative colitis. Part IV. Carcinoma of the colon. 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Br McdlJ 1966 i::1442-7.","journal-title":"Br McdlJ"},{"key":"ref_18","first-page":"1447","article-title":"Long-term proginosis ol ulcerative colitis","volume":"i:","author":"FT, Watts J.McK DeDomnbal; Watkinson(G, Goligher J.C.","year":"1966","unstructured":"Watts J McK. DeDomnbal FT, Watkinson(G, Goligher JC. Long-term proginosis ol ulcerative colitis. Br-Me(l J 1966; i: 1447-53.","journal-title":"Br-Me(l J"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/S0016-5085(19)33714-X","article-title":"An experienice of ulcerative colitis. 111. Long-terimi outcom11e","volume":"59","author":"Jalan, K.N.; Prescott, R.J.; Sircus, W.; tcia","year":"1970","unstructured":"Jalan KN, Prescott RJ, Sircus W, tcia. An experienice of ulcerative colitis. 111. Long-terimi outcom11e. 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Gasiroenteroloigv 1978; 74: 1120."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0016-5085(79)80119-5","article-title":"Malignant potential of chronic ulcerative colitis","volume":"76","author":"Nugent, F.W.; Colcher, Haggitt R.C.; H, Kutteruf; G.C.","year":"1979","unstructured":"Nugent FW, Haggitt RC. Colcher H, Kutteruf GC. Malignant potential of chronic ulcerative colitis. Gastroenterology 1979; 76: 1-5.","journal-title":"Gastroenterology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0016-5085(79)90279-8","article-title":"Smith 1I, ci atl. Cancer in universal and left-sided ulcerative colitis: Factors determining risk","volume":"77","author":"Greenstein, A.J.; Sachar, D.B.","year":"1979","unstructured":"Greenstein AJ, Sachar DB, Smith 1I, ci atl. Cancer in universal and left-sided ulcerative colitis: Factors determining risk. 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New York: Raven Press, 198t): 325-34."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000198426","article-title":"Clinical course of ulcerative colitis in Italy","volume":"20","author":"L(anfranchi, G.A.; Brignola, C.; Michelini, M.; tcial","year":"1980","unstructured":"L(anfranchi GA, Brignola C, Michelini M, tcial. Clinical course of ulcerative colitis in Italy. Digessioti 1980; 20: 106-10.","journal-title":"Digessioti"},{"key":"ref_27","first-page":"36","article-title":"Mortality in ulcerative colitis","volume-title":"Gaistroenterolo, g","volume":"83","author":"Gyde, S.N.; Prior, P.; Dew, M.J.; Saunders, V.; Waterhouse, J.A.H.; Alan, R.N.","year":"1982","unstructured":"Gyde SN, Prior P, Dew MJ, Saunders V, Waterhouse JAH, Alan RN. Mortality in ulcerative colitis. Gaistroenterolo,g 1982; 83: 36-43."},{"key":"ref_28","first-page":"54","article-title":"The patient record in epidemiology","volume":"245","author":"Kurland, L.T.; Molgaard, C.A.","year":"1981","unstructured":"Kurland LT, Molgaard CA. The patient record in epidemiology. Sci An 1981; 245: 54-63.","journal-title":"Sci An"},{"key":"ref_29","first-page":"47","article-title":"Elvebiack l R, Nobrega Fl. Population studies in Rochester and Olmsted County, Minnesota, 1900-1968","volume-title":"Thc comluntOitv' (i5 a cpidcttinologic, laboraiory. BtIlt inmore: I he Johns","author":"Kurland, LT","year":"1970","unstructured":"Kurland LT, Elvebiack l R, Nobrega Fl. Population studies in Rochester and Olmsted County, Minnesota, 1900-1968. In: Kessler 11, Levin ML, eds. Thc comluntOitv' (i5 a cpidcttinologic, laboraiory. 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(Gastroeniterology 1972: 62: 935-41.","journal-title":"(Gastroeniterology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/BF02553382","article-title":"Trends in right and leftsidcd colon cancer","volume":"26","author":"Beart, R.W.; Li, Mclton; Maruta, M.; Dockerty, M.B.; Frydenberg, H.B.; O'Fiillon, W.M.","year":"1983","unstructured":"Beart RW, Mclton Li, Maruta M, Dockerty MB, Frydenberg HB, O'Fiillon WM. Trends in right and leftsidcd colon cancer. Dis Colon Rectcm 1983: 26: 393-8.","journal-title":"Dis Colon Rectcm"},{"key":"ref_33","first-page":"143","article-title":"Thle.statistical anal-ysis of failure iinc (lata. Ncw","author":"Kalbflcish, J.D.; Prcntice, R.L.","year":"1980","unstructured":"Kalbflcish JD, Prcntice RL. Thle.statistical anal-ysis of failure iinc (lata. 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Cancer 1981: 48: 2742-5.","journal-title":"Cancer"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.28.10.1261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:41:33Z","timestamp":1763743293000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.28.10.1261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,10]]},"references-count":34,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1987,10,1]]},"published-print":{"date-parts":[[1987,10]]}},"alternative-id":["10.1136\/gut.28.10.1261"],"URL":"https:\/\/doi.org\/10.1136\/gut.28.10.1261","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,10]]}}}