{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T15:35:41Z","timestamp":1765640141123,"version":"3.48.0"},"reference-count":19,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1987,12]]},"abstract":"<jats:p>Twenty children with coeliac disease were diagnosed over a five year period in an area with 10,000-12,000 births per year. The average annual incidence was 1:3000 births. All children presented with severe symptoms and rickets was not uncommon (25%). Mean age at onset of symptoms was 38 months (range 6-120) and 72 months at the time of diagnosis (range 13-192), with a mean delay of 34 months. No cases were diagnosed during infancy. The difficulties in the differentiation of coeliac disease from the more common causes of chronic diarrhoea, and problems with diagnosis and management are discussed.<\/jats:p>","DOI":"10.1136\/gut.28.12.1595","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1595-1599","source":"Crossref","is-referenced-by-count":21,"title":["Coeliac disease among children in Kuwait: difficulties in diagnosis and management."],"prefix":"10.1136","volume":"28","author":[{"given":"F A","family":"Khuffash","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M H","family":"Barakat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A A","family":"Shaltout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S","family":"Farwana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M S","family":"Adnani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M F","family":"Tungekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1987,12,1]]},"reference":[{"key":"ref_1","first-page":"1233","article-title":"Coeliac disease in North Indian children","volume":"ii:","author":"Walia, B.N.S.; Sidhu, J.K.; Tandon, B.N.; Ghai, O.P.; Bhargava, S.","year":"1966","unstructured":"Walia BNS, Sidhu JK, Tandon BN, Ghai OP, Bhargava S. Coeliac disease in North Indian children. Br Med J 1966; ii: 1233-4.","journal-title":"Br Med J"},{"key":"ref_2","first-page":"348","article-title":"Coeliac disease in children of Asian immigrants","volume":"i:","author":"Nelson, R.; McNeish, A.S.; Anderson, C.M.","year":"1973","unstructured":"Nelson R, McNeish AS, Anderson CM. Coeliac disease in children of Asian immigrants. Lancet 1973; i: 348-50.","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/tropej\/21.4.178","article-title":"Coeliac disease in Iraqi children","volume":"21","author":"Al-Hassany, M.","year":"1975","unstructured":"Al-Hassany M. Coeliac disease in Iraqi children. J Trop Pediatr 1975; 21: 178-9.","journal-title":"J Trop Pediatr"},{"key":"ref_4","first-page":"121","article-title":"Coeliac disease in Sudanese children","volume-title":"Gut","volume":"19","author":"Suliman, G.I.","year":"1978","unstructured":"Suliman GI. Coeliac disease in Sudanese children. Gut 1978; 19: 121-5."},{"key":"ref_5","first-page":"128","article-title":"Coeliac disease in Cuban children","volume":"56","author":"Rabassa, E.B.; Sagaro, E.; Fragoso, T.; Castaneda, C.; Gra, B.","year":"1980","unstructured":"Rabassa EB, Sagaro E, Fragoso T, Castaneda C, Gra B. Coeliac disease in Cuban children. Arch Dis Child 1980; 56: 128-31.","journal-title":"Arch Dis Child"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1136\/gut.25.9.1009","article-title":"Coeliac disease in monozygotic twin girls. Synchronous presentation","volume":"25","author":"Khuffash, F.A.; Barakat, M.H.; Majeed, H.A.; White, A.G.; Beseda, A.J.","year":"1984","unstructured":"Khuffash FA, Barakat MH, Majeed HA, White AG, Beseda AJ. Coeliac disease in monozygotic twin girls. Synchronous presentation. Gut 1984; 25: 1009-12.","journal-title":"Gut"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/02724936.1982.11748243","article-title":"Gastroenteritis in a regional hospital in Kuwait: some aspects of the disease","volume":"2","author":"Khuffash, F.A.; Majeed, H.A.; Sethi, S.K.; Al-Nakib, W.","year":"1982","unstructured":"Khuffash FA, Majeed HA, Sethi SK, Al-Nakib W. Gastroenteritis in a regional hospital in Kuwait: some aspects of the disease. Ann Trop Paediatr 1982; 2: 123-8.","journal-title":"Ann Trop Paediatr"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/adc.47.252.292","article-title":"Coeliac disease. Some still controversial aspects","volume":"47","author":"Anderson, C.M.; Gracey, M.; Burke, V.","year":"1972","unstructured":"Anderson CM, Gracey M, Burke V. Coeliac disease. Some still controversial aspects. Arch Dis Child 1972; 47: 292-8.","journal-title":"Arch Dis Child"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0022-3476(81)80825-6","article-title":"Childhood coeliac disease - a reappraisal","volume":"98","author":"Lebenthal, E.; Branski, D.","year":"1981","unstructured":"Lebenthal E, Branski D. Childhood coeliac disease - a reappraisal. J Pediatr 1981; 98: 681-90.","journal-title":"J Pediatr"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1651-2227.1983.tb09772.x","article-title":"Peroral endoscopic biopsy in infants and children","volume":"72","author":"Barakat, M.H.; Ali, S.M.; Badawi, A.R.","year":"1983","unstructured":"Barakat MH, Ali SM, Badawi AR, et al. Peroral endoscopic biopsy in infants and children. Acta Paediatr Scand 1983; 72: 563-9.","journal-title":"Acta Paediatr Scand"},{"key":"ref_11","first-page":"97","article-title":"Biopsy pathology of the small intestine. Chapman and Hall","author":"Lee, F.D.; Tomer, P.G.","year":"1980","unstructured":"Lee FD, Tomer PG. Biopsy pathology of the small intestine. Chapman and Hall. London, 1980: pp 97-104."},{"key":"ref_12","article-title":"Physical growth and development","volume-title":"ofPaediatrics","author":"Tanner, J.M.","year":"1978","unstructured":"Tanner JM. Physical growth and development. In: Forfar JD, Arneil GC, eds. Textbook ofPaediatrics. 2nd edition. Churchill-Livingstone, 1978.","edition":"2nd edition"},{"key":"ref_13","first-page":"461","article-title":"Diagnostic criteria in coeliac disease","volume":"59","author":"Meeuwisse, G.W.","year":"1970","unstructured":"Meeuwisse GW. Diagnostic criteria in coeliac disease. Acta Paediatr Scand 1970; 59: 461-3.","journal-title":"Acta Paediatr Scand"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/adc.55.2.143","article-title":"Gluten intolerance, gluten enteropathy and coeliac disease","volume":"55","author":"Dodge, J.A.","year":"1980","unstructured":"Dodge JA. Gluten intolerance, gluten enteropathy and coeliac disease. Arch Dis Child 1980; 55: 143-5.","journal-title":"Arch Dis Child"},{"key":"ref_15","first-page":"703","article-title":"Incidence of coeliac disease in the West of Ireland","volume":"i:","author":"Mylotte, M.; Egan-Mitchell, B.; McCarthy, C.F.; McNichol, B.","year":"1979","unstructured":"Mylotte M, Egan-Mitchell B, McCarthy CF, McNichol B. Incidence of coeliac disease in the West of Ireland. Br Med J 1979; i: 703-5.","journal-title":"Br Med J"},{"key":"ref_16","article-title":"Coeliac disease is disappearing [letter]. Lancet 1980","author":"Littlewood, J.M.; Crollick, A.J.; Richards, I.D.G.","year":"1359","unstructured":"Littlewood JM, Crollick AJ, Richards IDG. Coeliac disease is disappearing [letter]. Lancet 1980; ii: 1359."},{"key":"ref_17","first-page":"494","article-title":"Childhood coeliac disease","volume":"i:","author":"Simila, S.; Kokkonen, J.; Voulokka, P.; Kouvalainen, K.","year":"1981","unstructured":"Simila S, Kokkonen J, Voulokka P, Kouvalainen K. Childhood coeliac disease. Lancet 1981; i: 494-5.","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/S0022-3476(83)80462-4","article-title":"Short stature and coeliac disease: a relationship to consider even in patients with no gastrointestinal manifestations","volume":"103","author":"Cacciari, E.; Salardi, S.; Lazzari, R.","year":"1983","unstructured":"Cacciari E, Salardi S, Lazzari R, et al. Short stature and coeliac disease: a relationship to consider even in patients with no gastrointestinal manifestations. J Pediatr 1983; 103:708-11.","journal-title":"J Pediatr"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/02724936.1984.11748320","article-title":"Basic epidemiological aspects of acute gastroenteritis in a regional hospital in Kuwait","volume":"4","author":"Khuffash, F.A.; Majeed, H.A.","year":"1984","unstructured":"Khuffash FA, Majeed HA. Basic epidemiological aspects of acute gastroenteritis in a regional hospital in Kuwait. Ann Trop Paediatr 1984; 4: 113-5.","journal-title":"Ann Trop Paediatr"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.28.12.1595","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T15:31:46Z","timestamp":1765639906000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.28.12.1595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,12]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[1987,12,1]]},"published-print":{"date-parts":[[1987,12]]}},"alternative-id":["10.1136\/gut.28.12.1595"],"URL":"https:\/\/doi.org\/10.1136\/gut.28.12.1595","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1987,12]]}}}