{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T15:25:38Z","timestamp":1780932338351,"version":"3.54.1"},"reference-count":12,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1988,7]]},"abstract":"<jats:p>The results of 250 consecutive ERCP examinations were analysed in order to assess whether or not juxtapapillary duodenal diverticula are associated with choledocholithiasis. Cholangiography showed common bile duct stones in 71 patients of whom 25 (35%) had periampullary diverticula. Clear bile ducts were shown in 99, of whom only 12 had diverticula (12%) (p less than 0.05). After allowing for the differences in age between the two groups, patients with choledocholithiasis were 2.6 times (95% CI: 1.14-5.93) more likely to have a periampullary diverticulum than patients without choledocholithiasis. In the remaining 80 patients, cholangiography was either not successful or not indicated. Further clinical follow up and\/or investigation have failed to reveal duct stones in any and only 10 (13%) of these 80 patients had diverticula. Overall, 47 patients had diverticula: 25 (53%) had duct stones, four may have had stones and 18 had none. Three or more years after cholecystectomy 59% of patients with duct stones had diverticula, while only 13% with clear ducts had them. These results show a significant association between periampullary duodenal diverticula and choledocholithiasis.<\/jats:p>","DOI":"10.1136\/gut.29.7.1003","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1003-1006","source":"Crossref","is-referenced-by-count":40,"title":["Are duodenal diverticula associated with choledocholithiasis?"],"prefix":"10.1136","volume":"29","author":[{"given":"R H","family":"Kennedy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M H","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1988,7,1]]},"reference":[{"key":"ref_1","first-page":"37","article-title":"L'Institut de France, Academie des","volume":"1710","author":"de l'Academie Royalk, Chomel J.B.L.Histoire; Paris","unstructured":"Chomel JBL. Histoire de l'Academie Royalk, Paris. L'Institut de France, Academie des Sciences, 1710: 37.","journal-title":"Sciences"},{"key":"ref_2","article-title":"De sedibus et causis morborum. Epist 34: Par 17","author":"Morgagni, G.B.","year":"1762","unstructured":"Morgagni GB. De sedibus et causis morborum. Epist 34: Par 17. Naples, 1762."},{"key":"ref_3","first-page":"258","article-title":"On the frequency and age incidence of duodenal diverticula","volume":"33","author":"Grant, J.C.B.","year":"1935","unstructured":"Grant JCB. On the frequency and age incidence of duodenal diverticula. Can Med Assoc J 1935; 33: 258-62.","journal-title":"Can Med Assoc J"},{"key":"ref_4","first-page":"121","article-title":"Duodenal diverticula in man. Anat Rec 1911; 5","author":"Baldwin, W.M.","unstructured":"Baldwin WM. Duodenal diverticula in man. Anat Rec 1911;5: 121-39."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00000658-194303000-00007","article-title":"Diverticula and variations of the duodenum","volume":"117","author":"Ackerman, W.","year":"1943","unstructured":"Ackerman W. Diverticula and variations of the duodenum. Ann Surg 1943; 117: 403-13.","journal-title":"Ann Surg"},{"key":"ref_6","first-page":"230","article-title":"Diverticulosis of the small intestine","volume":"103","author":"Edwards, H.C.","year":"1936","unstructured":"Edwards HC. Diverticulosis of the small intestine. Ann Surg 1936; 103: 230-54."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1001\/archsurg.1964.01310200113023","article-title":"Duodenal diverticulum: a clinical evaluation","volume":"88","author":"Whitcomb, J.G.","year":"1964","unstructured":"Whitcomb JG. Duodenal diverticulum: a clinical evaluation. Arch Surg 1964; 88: 275-8.","journal-title":"Arch Surg"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3109\/00365527809179812","article-title":"Bacteriological studies of common bile duct bile in patients with gallstone disease and juxtapapillary duodenal diverticula","volume":"13","author":"Lotveit, T.; Osnes, M.; Aune, S.","year":"1978","unstructured":"Lotveit T, Osnes M, Aune S. Bacteriological studies of common bile duct bile in patients with gallstone disease and juxtapapillary duodenal diverticula. Scand J Gastroenterol 1978; 13: 93-5.","journal-title":"Scand J Gastroenterol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3109\/00365528009181545","article-title":"Studies of the choledochoduodenal sphincter in patients with and without juxta-papillary duodenal diverticula","volume":"15","author":"Lotveit, T.; Osnes, M.; Aune, S.; Larsen, S.","year":"1980","unstructured":"Lotveit T, Osnes M, Aune S, Larsen S. Studies of the choledochoduodenal sphincter in patients with and without juxta-papillary duodenal diverticula. Scand J Gastroenterol 1980; 15: 875-80.","journal-title":"Scand J Gastroenterol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3109\/00365528109181962","article-title":"Biliary pigment and cholesterol calculi in patients with and without juxtapapillary duodenal diverticula","volume":"16","author":"Lotveit, T.; Foss, O.P.; Osnes, M.","year":"1981","unstructured":"Lotveit T, Foss OP, Osnes M. Biliary pigment and cholesterol calculi in patients with and without juxtapapillary duodenal diverticula. Scand J Gastroenterol 1981; 16: 241-4.","journal-title":"Scand J Gastroenterol"},{"key":"ref_11","first-page":"743","article-title":"The post-cholecystectomy interval influences the composition of common bile duct gallstones","volume":"2","author":"Malet, P.F.; Huang, G.; Long, W.B.; Trotman, B.W.; Soloway, R.D.","year":"1982","unstructured":"Malet PF, Huang G, Long WB, Trotman BW, Soloway RD. The post-cholecystectomy interval influences the composition of common bile duct gallstones [Abstract]. Hepatology 1982; 2: 743.","journal-title":"Hepatology"},{"key":"ref_12","first-page":"62","article-title":"The pathological implication of duodenal diverticula","volume":"154","author":"Eggert, A.; Teichmann, W.; Wittmann, D.H.","year":"1982","unstructured":"Eggert A, Teichmann W, Wittmann DH. The pathological implication of duodenal diverticula. Surg Gynecol Obstet 1982; 154: 62-4.","journal-title":"Surg Gynecol Obstet"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.29.7.1003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:46:07Z","timestamp":1763747167000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.29.7.1003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,7]]},"references-count":12,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1988,7,1]]},"published-print":{"date-parts":[[1988,7]]}},"alternative-id":["10.1136\/gut.29.7.1003"],"URL":"https:\/\/doi.org\/10.1136\/gut.29.7.1003","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,7]]}}}