{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:43:03Z","timestamp":1765600983874,"version":"3.48.0"},"reference-count":10,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:p>The nature, frequency, severity, and possible causes of complications after 207 sphincter of Oddi manometry measurements were studied in 146 patients. Acute pancreatitis was diagnosed in 6% (12 of 207) of the investigations and in 8% (12 of 146) of the patients examined. The pancreatitis was mild in all patients. After cannulation of the pancreatic duct, acute pancreatitis occurred in 10 of 95 (11%) patients compared with one of 93 (1%) when the manometry catheter entered the bile duct only (p less than 0.02). Seven (58%) of the patients who developed acute pancreatitis, however, were found to be suffering from chronic pancreatitis. Some 26% of all sphincter of Oddi manometry measurements on patients with this diagnosis were complicated by an acute attack of pancreatitis compared with 3% (p less than 0.001) in patients without signs of chronic pancreatitis. In all patients the pancreatitis developed within three hours of manometry. We conclude that pancreatitis may occasionally follow sphincter of Oddi manometry measurement, even in patients without pancreaticobiliary disease, and that underlying chronic pancreatitis constitutes a definite risk. Sphincter of Oddi manometry measurement in control subjects should therefore be performed only in centres where the safety of the procedure has been established, and the presence of chronic pancreatitis should be excluded beforehand. Cannulation of the pancreatic duct should be avoided. Manometry can be safely performed, however, as an outpatient procedure.<\/jats:p>","DOI":"10.1136\/gut.31.7.821","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"821-824","source":"Crossref","is-referenced-by-count":71,"title":["Pancreatitis after sphincter of Oddi manometry."],"prefix":"10.1136","volume":"31","author":[{"given":"P","family":"Rolny","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Anderberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Ihse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Lindstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Olaison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Arvill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1990,7,1]]},"reference":[{"key":"ref_1","first-page":"915","article-title":"Etiopathogenesis and definitions of chronic pancreatitis","volume":"31","author":"Sarles, H.","year":"1986","unstructured":"Sarles H. Etiopathogenesis and definitions of chronic pancreatitis. DigDisSci 1986; 31: 915-1075.","journal-title":"DigDisSci"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1136\/gut.25.10.1107","article-title":"Pancreatography in chronic pancreatitis: international definitions","volume":"25","author":"Axon, A.T.R.; Classen, M.; Cotton, P.B.; Cremer, M.; Freeny, P.C.; Lees, W.R.","year":"1984","unstructured":"Axon ATR, Classen M, Cotton PB, Cremer M, Freeny PC, Lees WR. Pancreatography in chronic pancreatitis: international definitions. Gut 1984; 25: 1107-12.","journal-title":"Gut"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1136\/gut.27.12.1507","article-title":"Paradoxical response of sphincter of Oddi to intravenous injection of cholecystokinin or ceruletide. Manometric findings and results of treatment in biliary dyskinesia","volume":"27","author":"Rolny, P.; Arelback, A.; Funch-Jensen, P.; Kruse, A.; Ravnsbaeck, J.; Jarnerot, G.","year":"1986","unstructured":"Rolny P, Arelback A, Funch-Jensen P, Kruse A, Ravnsbaeck J, Jarnerot G. Paradoxical response of sphincter of Oddi to intravenous injection of cholecystokinin or ceruletide. Manometric findings and results of treatment in biliary dyskinesia. Gut 1986; 27: 1507-11.","journal-title":"Gut"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-2007-1018170","article-title":"Pharmacology of the sphincter of Oddi","volume":"20","author":"Staritz, M.","year":"1988","unstructured":"Staritz M. Pharmacology of the sphincter of Oddi. Endoscopv 1988; 20: 171-4.","journal-title":"Endoscopv"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF01307970","article-title":"Endoscopic manometrv of pancreatic and biliary sphincter zones in man. Basal results in healthy volunteers","volume":"26","author":"Carr-Locke, D.L.; Gregg, J.A.","year":"1981","unstructured":"Carr-Locke DL, Gregg JA. Endoscopic manometrv of pancreatic and biliary sphincter zones in man. Basal results in healthy volunteers. Dig Dis Sci 1981; 26: 7-15.","journal-title":"Dig Dis Sci"},{"key":"ref_6","first-page":"209","article-title":"Prognostic signs and non-operative peritoneal lavage in acute pancreatitis","volume":"143","author":"Ranson, J.H.C.; Rifkind, K.M.; Turner, J.W.","year":"1976","unstructured":"Ranson JHC, Rifkind KM, Turner JW. Prognostic signs and non-operative peritoneal lavage in acute pancreatitis. Surg Gvnecol Obstet 1976; 143: 209-19.","journal-title":"Surg Gvnecol Obstet"},{"key":"ref_7","first-page":"341","article-title":"Sphincter of Oddi manometry: the control population","volume":"17","author":"Carr-Locke, D.L.","year":"1985","unstructured":"Carr-Locke DL. Sphincter of Oddi manometry: the control population. ItalJ Gastroenterol 1985; 17: 341-3.","journal-title":"ItalJ Gastroenterol"},{"key":"ref_8","first-page":"185","article-title":"Sphincter of Oddi manometry: a survey of methodology, complications and clinical application","volume":"34","author":"EL, Jr, Cattau; DA, Johnson; SB, Benjamin; JE, Geenen; WJ, Hogan","year":"1988","unstructured":"Cattau EL Jr, Johnson DA, Benjamin SB, Geenen JE, Hogan WJ. Sphincter of Oddi manometry: a survey of methodology, complications and clinical application. Gastrointest Endosc 1988; 34: 185.","journal-title":"Gastrointest Endosc"},{"key":"ref_9","first-page":"227","article-title":"Pancreatitis due to endoscopic biliary manometrv: proceed with caution","volume":"94","author":"King, C.E.; Kalvaria, I.; Sninskv, C.A.","year":"1988","unstructured":"King CE,Kalvaria I, Sninskv CA. Pancreatitis due to endoscopic biliary manometrv: proceed with caution. Gastroenterologv 1988; 94: A227.","journal-title":"Gastroenterologv"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S0016-5107(88)71371-1","article-title":"Severe acute pancreatitis complicating sphincter of Oddi manometry","volume":"34","author":"Albert, M.B.; Steinberg, W.M.; Irani, S.K.","year":"1988","unstructured":"Albert MB, Steinberg WM, Irani SK. Severe acute pancreatitis complicating sphincter of Oddi manometry. Gastrointest Endosc 1988; 34: 342-5.","journal-title":"Gastrointest Endosc"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.31.7.821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:38:45Z","timestamp":1765600725000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.31.7.821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1990,7,1]]},"published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1136\/gut.31.7.821"],"URL":"https:\/\/doi.org\/10.1136\/gut.31.7.821","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}