{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:09:56Z","timestamp":1791216596614,"version":"4.1.0"},"reference-count":14,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1992,6]]},"abstract":"<jats:p>Pain site and radiation and the effect of various foods were studied prospectively in a consecutive series of patients with chronic upper abdominal pain. Patients followed for less than one year were excluded unless peptic ulcer or abdominal malignancy had been diagnosed or laparotomy had been carried out. A total of 632 patients were eligible for the first study and 431 for the second. Gastric ulcer pain was more likely to be left hypochondrial (17%) compared with pain from duodenal ulcer (4%) or from all other conditions (5%). It was less likely to be epigastric (54%) compared with duodenal ulcer pain (75%). Oesophageal pain was more likely to be both retrosternal and epigastric (25%) compared with non-oesophageal pain (2%). Radiation to the back was more common in peptic ulcer (31%) and biliary pain (35%) compared with functional pain (20%). Pain precipitation by fatty foods was commoner in biliary disease (40%) than in duodenal ulcer (11%), peptic ulcer (9%), or non-ulcer dyspepsia (19%). Orange, alcohol, and coffee precipitated pain more frequently in duodenal ulcer (41%, 50%, and 43% respectively) than in biliary disease (17%, 0%, and 14% respectively). Chilli precipitated pain in one quarter to one half of subjects regardless of diagnosis. Approximately one tenth of all subjects avoided chilli, curry, coffee, and tea because of medical or other advice.<\/jats:p>","DOI":"10.1136\/gut.33.6.743","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"743-748","source":"Crossref","is-referenced-by-count":42,"title":["Chronic upper abdominal pain: site and radiation in various structural and functional disorders and the effect of various foods."],"prefix":"10.1136","volume":"33","author":[{"given":"J Y","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H H","family":"Tay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1992,6,1]]},"reference":[{"key":"ref_1","first-page":"232","article-title":"The alimentary and genito-urinary system","author":"French, E.B.","year":"1968","unstructured":"French EB. The alimentary and genito-urinary system. 2nd ed. In: Macleod, J, ed. Clinical Examination. Edinburgh: Livingstone, 1968: 232-74.","edition":"2nd ed"},{"key":"ref_2","first-page":"653","article-title":"Towards positive diagnosis of the irritable bowel","volume":"3","author":"Manning, A.P.; Thompson, W.G.; Heaton, K.W.; Morris, A.F.","year":"1978","unstructured":"Manning AP, Thompson WG, Heaton KW, Morris AF. Towards positive diagnosis of the irritable bowel. BMJ 1978; 3:653-4.","journal-title":"BMJ"},{"key":"ref_3","first-page":"43","article-title":"Irritable bowel syndrome: phvsical signs and investigations","volume-title":"Imrtable bowel svndrome","author":"Fielding, J.F.","year":"1985","unstructured":"Fielding JF. Irritable bowel syndrome: phvsical signs and investigations. In: Read NW, ed. Imrtable bowel svndrome. 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Discriminant value of dyspeptic symptoms: a studv of the clinical presentation of 221 patients with dvspepsia of unknown cause, peptic ulceration, and cholelithiasis. (Git 1987; 28: 40-6."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0016-5085(76)80211-9","article-title":"Computerized questionaire analvsis of duodenal ulcer symptoms","volume":"71","author":"Earlam, R.","year":"1976","unstructured":"Earlam R. Computerized questionaire analvsis of duodenal ulcer symptoms. Gastroenterology 1976; 71: 314-7.","journal-title":"Gastroenterology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0140-6736(72)91683-2","article-title":"Some clinical observations on patients with gallstones","volume":"ii:","author":"Gunn, A.; Keddie, N.","year":"1972","unstructured":"Gunn A, Keddie N. Some clinical observations on patients with gallstones. 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GCt 1985; 26: 783-8.","journal-title":"GCt"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.33.6.743","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T16:00:51Z","timestamp":1765641651000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.33.6.743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,6]]},"references-count":14,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1992,6,1]]},"published-print":{"date-parts":[[1992,6]]}},"alternative-id":["10.1136\/gut.33.6.743"],"URL":"https:\/\/doi.org\/10.1136\/gut.33.6.743","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,6]]}}}