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The basal and pentagastrin stimulated secretion of acid, pepsin, and histamine were measured and no changes in acid or pepsin secretion were shown to occur (risk of type II error &lt; 1%). It is therefore concluded that this chronic ulcer is a model of impaired duodenal defence.<\/jats:p>","DOI":"10.1136\/gut.33.8.1044","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1044-1049","source":"Crossref","is-referenced-by-count":3,"title":["Duodenal ulcer: a model of impaired mucosal defence."],"prefix":"10.1136","volume":"33","author":[{"given":"R H","family":"Gompertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A S","family":"Michalowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W K","family":"Man","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J H","family":"Baron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1992,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/bjs.1800760502","article-title":"Current indications for elective peptic ulcer surgery","volume":"76","author":"Taylor, T.V.","year":"1989","unstructured":"Taylor TV. 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