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The possibility that relative antral hypoacidity induced by regular smoking produces an increase in parietal cell mass via a feedback mechanism mediated by gastrin is discussed: such a mechanism would explain the previously reported positive correlation between maximal gastric secretion of acid and the total dose of cigarettes.<\/jats:p>","DOI":"10.1136\/gut.33.9.1170","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1170-1173","source":"Crossref","is-referenced-by-count":10,"title":["Effect of acute cigarette smoking on gastric secretion."],"prefix":"10.1136","volume":"33","author":[{"given":"J C","family":"Roxburgh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P F","family":"Whitfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hobsley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1992,9,1]]},"reference":[{"key":"ref_1","first-page":"918","article-title":"Smoking and gastric hypersecretion in duodenal ulcer patients","volume":"20","author":"Whitfield, P.F.; Hobsley, M.","year":"1979","unstructured":"Whitfield PF, Hobsley M. 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