{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:09:58Z","timestamp":1778857798138,"version":"3.51.4"},"reference-count":37,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:p>This study aimed to determine the prevalence of dyspeptic symptoms and premalignant gastric lesions in coal miners and sex matched population control subjects. Retired coal miners and men from the general population in north Nottinghamshire were sent a dyspepsia questionnaire to fill in, and those with upper gastrointestinal symptoms were invited for gastroscopy and biopsy. A total of 1272 men from the general population and 2099 retired coal miners aged 50-75 years took part in the study. Some 977 of 1272 (76.8%) control subjects and 1715 of 2099 (81.7%) miners replied to the questionnaire. A total of 308 of 977 (31.5%) controls and 620 of 1715 (36.2%) miners were positive for at least one symptom. There was a highly significant difference between the numbers of surface mine and underground workers who reported dyspeptic symptoms (66 of 300 (22%) v 425 of 1083 (32.2%) of p &lt; 0.0001). Histology showed that significantly more miners than controls had acute on chronic gastritis (22 v 11%; p = 0.01) and intestinal metaplasia (23 v 8%; p = &lt; 0.0001). Coal miners may be a suitable group for gastric premalignancy screening using an upper gastrointestinal symptom questionnaire and upper gastrointestinal endoscopy.<\/jats:p>","DOI":"10.1136\/gut.34.4.494","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"494-498","source":"Crossref","is-referenced-by-count":7,"title":["Screening for gastric carcinoma in coal miners."],"prefix":"10.1136","volume":"34","author":[{"given":"J D","family":"Harrison","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D L","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J D","family":"Hardcastle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1993,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/bjc.1962.69","article-title":"On the death rates from cancer of the stomach and respiratory diseases in 1949-53 among coal miners and other male residents in counties of England and Wales","volume":"16","author":"Stocks, P.","year":"1961","unstructured":"Stocks P. On the death rates from cancer of the stomach and respiratory diseases in 1949-53 among coal miners and other male residents in counties of England and Wales. Br J Cancer 1961; 16: 592.","journal-title":"Br J Cancer"},{"key":"ref_2","article-title":"Statistical Review for England and Wales 1937-1973","author":"General, Registrar","year":"1937","unstructured":"Registrar General. Statistical Review for England and Wales 1937-1973. London: HMSO, 1937."},{"key":"ref_3","first-page":"226","article-title":"Outcome of gastric carcinoma detected by gastric mass survey in Japan","volume":"18","author":"Kaneko, E.; Nakamura, T.; Umeda, N.; Fujino, M.; Niwa, H.","year":"1977","unstructured":"Kaneko E, Nakamura T, Umeda N, Fujino M, Niwa H. Outcome of gastric carcinoma detected by gastric mass survey in Japan. Gut 1977; 18: 226.","journal-title":"Gut"},{"key":"ref_4","first-page":"185","article-title":"Evaluation of gastric mass survey","volume":"146","author":"Okui, K.; Teiima, H.","year":"1980","unstructured":"Okui K, Teiima H. Evaluation of gastric mass survey. Acta ChirScand 1980; 146: 185.","journal-title":"Acta ChirScand"},{"key":"ref_5","first-page":"67","article-title":"A study on the efficiency of gastric cancer screening with special reference to the appropriate frequency of screening","volume":"78","author":"Kohrogi, N.","year":"1987","unstructured":"Kohrogi N. A study on the efficiency of gastric cancer screening with special reference to the appropriate frequency of screening. Fukuoka Igaku Zasshi 1987; 78: 67.","journal-title":"Fukuoka Igaku Zasshi"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/bjs.1800740728","article-title":"Accuracy of identification of early gastric cancer","volume":"74","author":"Ballantyne, K.; DL, D.M.; Jones, J.; RH, R.G.; Hardcastle, J.","year":"1987","unstructured":"Ballantyne K, DL DM, Jones J, RH RG, Hardcastle J. Accuracy of identification of early gastric cancer. Br] Surg 1987; 74:618.","journal-title":"Br] Surg"},{"key":"ref_7","article-title":"Stomach cancer mortality in Worksop and other Nottinghamshire mining towns","author":"Davies, J.","unstructured":"Davies J. Stomach cancer mortality in Worksop and other Nottinghamshire mining towns. Br]7 Cancer 1980; 41 (3): 438."},{"key":"ref_8","first-page":"777","article-title":"Gastric cancer in coal miners: final report","volume":"44","author":"CW, Swaen G.Aerdts; JJ, Slangen","year":"1987","unstructured":"Swaen G Aerdts CW, Slangen JJ. 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Cancer 1972; 29: 733.","journal-title":"Cancer"},{"key":"ref_11","first-page":"795","article-title":"Cause specific mortality of coal miners","author":"Rockette, H.","year":"1977","unstructured":"Rockette H. Cause specific mortality of coal miners. - Occup Med 1977; 19 (12): 795."},{"key":"ref_12","first-page":"337","article-title":"and clearance of inhaled particles","volume":"37","author":"Lippmann, M.; Yeates, D.; Deposition, Albert R.; retention","year":"1980","unstructured":"Lippmann M, Yeates D, Albert R. Deposition, retention, and clearance of inhaled particles. Br] mId Med 1980; 37: 337.","journal-title":"Br] mId Med"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0165-1161(75)90046-1","article-title":"Methods for detecting carcinogens and mutagens with the salmonella\/mammalian microsome mutagenicity test","volume":"31","author":"Ames, B.; McCann, J.; Yamasaki, E.","year":"1975","unstructured":"Ames B, McCann J, Yamasaki E. 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Am]7 Epidemiol 1986; 123: 30."},{"key":"ref_32","first-page":"209","article-title":"Cancer mortality in the British rubber industry","volume":"39","author":"Parkes, H.; Veys, C.; Waterhouse, J.; Peters, A.","year":"1982","unstructured":"Parkes H, Veys C, Waterhouse J, Peters A. Cancer mortality in the British rubber industry. Br 7 Ind Med 1982; 39: 209.","journal-title":"Br 7 Ind Med"},{"key":"ref_33","first-page":"363","article-title":"Cancer mortality in the British rubber industry: 1946-1980","volume":"43","author":"Sorahan, T.; Parkes, H.; Veys, C.; Waterhouse, J.","year":"1986","unstructured":"Sorahan T, Parkes H, Veys C, Waterhouse J. Cancer mortality in the British rubber industry: 1946-1980. Br ] Ind Med 1986; 43: 363.","journal-title":"Br"},{"key":"ref_34","first-page":"225","article-title":"An epidemiological survey of eight oil refineries in Britain","volume":"38","author":"Rushton, L.; Alderson, M.","year":"1981","unstructured":"Rushton L, Alderson M. 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