{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T05:29:05Z","timestamp":1768282145193,"version":"3.49.0"},"reference-count":20,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1994,3]]},"abstract":"<jats:p>An ileitis developing years or months after ileostomy was recognised and described many years ago but has rarely been mentioned since. We describe nine patients with a non-specific preanastomotic ileitis that developed years after colectomy in patients operated on for ulcerative colitis or carcinoma. The disease developed after various types of reconstruction: ileorectal, ileoanal, with or without pouch. The diseased ileum showed inflammation, erosions, ulcerations, and sometimes strictures. The disease course ranged from asymptomatic to severe pain and diarrhoea. No specific cause could be shown. Granulomas, infectious agents or ischaemic changes were not found. The anastomosis was always patent. Three patients have had numerous episodes of intestinal obstruction presumably because of adhesions. Seven of nine patients were female. The response to steroids, 5-aminosalicylic acid preparations, and methotrexate was poor, three patients responded well to azathioprine. The condition is not rare and the cause remains unknown.<\/jats:p>","DOI":"10.1136\/gut.35.3.373","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"373-376","source":"Crossref","is-referenced-by-count":15,"title":["Ileitis after colectomy for ulcerative colitis or carcinoma."],"prefix":"10.1136","volume":"35","author":[{"given":"A","family":"Hallak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Baratz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Santo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Halpern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Rabau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Werbin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Gilat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00000658-195201000-00002","article-title":"Results of the surgical treatment of ulcerative colitis","volume":"135","author":"Ripstein, C.B.; Miller, G.G.; Gardner, C.M.","year":"1952","unstructured":"Ripstein CB, Miller GG, Gardner CM. Results of the surgical treatment of ulcerative colitis. Ann Surg 1952; 135: 14-8.","journal-title":"Ann Surg"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S0140-6736(52)91133-1","article-title":"The surgical treatment of ulcerative colitis","volume":"ii:","author":"Counsell, P.B.; Goligher, J.C.","year":"1952","unstructured":"Counsell PB, Goligher JC. The surgical treatment of ulcerative colitis. Lancet 1952; ii: 1045-50.","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0140-6736(52)92149-1","article-title":"The management of an ileostomy","volume":"ii:","author":"Brooke, B.N.","year":"1952","unstructured":"Brooke BN. The management of an ileostomy. Lancet 1952; ii: 102-4.","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1001\/archsurg.1969.01340140095014","article-title":"Intra abdominal 'reservoir' in patients with permanent ileostomy; preliminary observations on a procedure resulting in fecal 'continence' in five ileostomy patients","volume":"99","author":"Kock, N.G.","year":"1986","unstructured":"Kock NG, Intra abdominal 'reservoir' in patients with permanent ileostomy; preliminary observations on a procedure resulting in fecal 'continence' in five ileostomy patients. Arch Surg 1986; 99: 223-30.","journal-title":"Arch Surg"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1136\/bmj.1.5494.1001","article-title":"Three hundred cases of diffuse ulcerative colitis treated by total colectomy and ileo-rectal anastomosis","volume":"1","author":"Aylett, S.O.","year":"1966","unstructured":"Aylett SO. Three hundred cases of diffuse ulcerative colitis treated by total colectomy and ileo-rectal anastomosis. BMJ 1966; 1:1001-5.","journal-title":"BMJ"},{"key":"ref_6","first-page":"459","article-title":"Total colectomy and endorectal ileal pullthrough with internal ileal reservoir for ulcerative colitis. Surg Gynecol Obstet 1980","volume":"23","author":"Fonkalsrud, E.W.","year":"1980","unstructured":"Fonkalsrud EW. Total colectomy and endorectal ileal pullthrough with internal ileal reservoir for ulcerative colitis. Surg Gynecol Obstet 1980; 150: 1-8 7 Utsunomiya J, Iwama T, Imajo M, Matsuo S, Sawai S, Yaegashi K, et al. Total colectomy, mucosal proctectomy and ileoanal anastomosis. Dis Colon Rectum 1980; 23: 459-65.","journal-title":"Dis Colon Rectum; Total colectomy, mucosal proctectomy and ileoanal anastomosis"},{"key":"ref_7","first-page":"564","article-title":"Restorative proctocolectomy: The four loop (W) reservoir","volume":"74","author":"Nicholls, R.J.; Lubowski, D.Z.","year":"1987","unstructured":"Nicholls RJ, Lubowski DZ. Restorative proctocolectomy: The four loop (W) reservoir. BMJ 1987; 74: 564-6.","journal-title":"BMJ"},{"key":"ref_8","first-page":"533","article-title":"Proctocolectomy with ileoanal reservoir and anal anastomosis","volume-title":"BrJ3 Surg","volume":"67","author":"Parks, A.G.; Nicholls, R.J.; Bellivea, P.","year":"1980","unstructured":"Parks AG, Nicholls RJ, Bellivea P. Proctocolectomy with ileoanal reservoir and anal anastomosis. BrJ3 Surg 1980; 67: 533-8."},{"key":"ref_9","first-page":"555","article-title":"Ileostomy for ulcerative colitis: technique, complications and management","volume":"93","author":"Warren, R.; McKittrick, L.S.","year":"1951","unstructured":"Warren R, McKittrick LS. Ileostomy for ulcerative colitis: technique, complications and management. Surg Gynecol Obstet 1951; 93: 555-67.","journal-title":"Surg Gynecol Obstet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0016-5085(19)36121-9","article-title":"Chronic ulcerative colitis: early and late experiences of 124 patients with ileal stomas","volume":"27","author":"Rogers, A.G.; Bargen, J.A.; Black, B.M.","year":"1954","unstructured":"Rogers AG, Bargen JA, Black BM. Chronic ulcerative colitis: early and late experiences of 124 patients with ileal stomas. Gastroenterology 1954; 27: 383-98.","journal-title":"Gastroenterology"},{"key":"ref_11","first-page":"784","article-title":"The complications of ileostomy","volume":"36","author":"Lyons, A.S.; Garlock, H.J.","year":"1954","unstructured":"Lyons AS, Garlock HJ. The complications of ileostomy. Surgery 1954; 36: 784-9.","journal-title":"Surgery"},{"issue":"42","key":"ref_12","first-page":"547","article-title":"Ileitis after ileostomy: prestomal ileitis","volume":"1962","author":"Thayer, W.R.; Spiro, H.M.","unstructured":"Thayer WR, Spiro HM. Ileitis after ileostomy: prestomal ileitis. Gastroenterology 1962; 42: 547-54.","journal-title":"Gastroenterology"},{"key":"ref_13","first-page":"688","article-title":"Ileitis and pouchitis after colectomy for ulcerative colitis","volume":"76","author":"Scott, A.D.; Phillips, R.K.S.","year":"1989","unstructured":"Scott AD, Phillips RKS. Ileitis and pouchitis after colectomy for ulcerative colitis. BrJ Surg 1989; 76: 688-9.","journal-title":"BrJ Surg"},{"key":"ref_14","first-page":"399404","article-title":"Complications of surgical treatment of chronic ulcerative colitis","volume":"72","author":"Colcock, B.P.; Mathiesen, W.L.","year":"1956","unstructured":"Colcock BP, Mathiesen WL. Complications of surgical treatment of chronic ulcerative colitis. Arch Surg 1956; 72: 399404.","journal-title":"Arch Surg"},{"issue":"153","key":"ref_15","first-page":"241","article-title":"Intestinal obstruction following total colectomy for ulcerative colitis","volume":"1961","author":"Tolstedt, G.E.; Bell, J.W.","unstructured":"Tolstedt GE, Bell JW. Intestinal obstruction following total colectomy for ulcerative colitis. 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Dis Colon Rectum 1964; 7: 427-35.","journal-title":"Dis Colon Rectum"},{"key":"ref_18","first-page":"287","article-title":"Prestomal ileitis: clinical and pathological findings in five cases","volume":"154","author":"Knill-Jones, R.P.; Morson, B.; Williams, R.","year":"1970","unstructured":"Knill-Jones RP, Morson B, Williams R. Prestomal ileitis: clinical and pathological findings in five cases. Q J Med 1970; 154: 287-97.","journal-title":"Q J Med"},{"key":"ref_19","first-page":"516","article-title":"Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs","volume":"41","author":"Lang, J.; Price, A.B.; Levi, A.J.; Burke, H.; lJM, Gumpel; Bjarnason, I.","year":"1988","unstructured":"Lang J, Price AB, Levi AJ, Burke H, Gumpel lJM, Bjarnason I. Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs. JClinPathol 1988; 41: 516-26.","journal-title":"JClinPathol"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1056\/NEJM199209103271101","article-title":"Gastrointestinal damage associated with the use of nonsteroidal anti-inflammatory drugs","volume":"327","author":"Allison, M.C.; Howatson, A.G.; Torrance, C.J.; Lee, F.D.; Russell, R.I.","year":"1992","unstructured":"Allison MC, Howatson AG, Torrance CJ, Lee FD, Russell RI. Gastrointestinal damage associated with the use of nonsteroidal anti-inflammatory drugs. N Engl7 Med 1992; 327: 749-54.","journal-title":"N Engl7 Med"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.35.3.373","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T14:16:58Z","timestamp":1765635418000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.35.3.373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3]]},"references-count":20,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1994,3,1]]},"published-print":{"date-parts":[[1994,3]]}},"alternative-id":["10.1136\/gut.35.3.373"],"URL":"https:\/\/doi.org\/10.1136\/gut.35.3.373","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,3]]}}}