{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:54:44Z","timestamp":1791071684410,"version":"4.1.0"},"reference-count":29,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1995,2,1]]},"DOI":"10.1136\/gut.36.2.193","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:41:31Z","timestamp":1190151691000},"page":"193-197","source":"Crossref","is-referenced-by-count":31,"title":["Effect of Helicobacter pylori eradication on gastric metaplasia of the duodenum."],"prefix":"10.1136","volume":"36","author":[{"given":"S","family":"Khulusi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Mendall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Badve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Finlayson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T C","family":"Northfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(84)91816-6","article-title":"Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration","volume":"i:","author":"Marshall, B.J.; Warren, JR","year":"1984","unstructured":"Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984 i: 1311-5.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0016-5085(89)80057-5","article-title":"Campylobacter pylori and peptic ulcer disease","volume":"96","author":"Graham, D.Y.","year":"1989","unstructured":"Graham DY. Campylobacter pylori and peptic ulcer disease. Gastroenterology 1989; 96: 615-25.","journal-title":"Gastroenterology"},{"key":"ref_3","first-page":"1","volume":"187","author":"Tytgat, G.N.; Noach, L.; pylori, Rauws E.A.Helicobacter","year":"1991","unstructured":"Tytgat GN, Noach L, Rauws EA. Helicobacter pylori. Scand J Gastroenterol Suppl 1991; 187: 1-8.","journal-title":"Scand J Gastroenterol Suppl"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1093\/infdis\/161.4.626","article-title":"Helicobacter pylori and the pathogenesis of gastroduodenal inflammation","volume":"161","author":"Blaser, M.J.","year":"1990","unstructured":"Blaser MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 1990; 161: 626-33.","journal-title":"J Infect Dis"},{"key":"ref_5","first-page":"1439","article-title":"Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori","volume":"ii:","author":"Marshall, B.J.; Goodwin, C.S.; Warren, JR, Murray; R, Blincow; ED, Blackbourn; S.J.","year":"1988","unstructured":"Marshall BJ, Goodwin CS, Warren JR, Murray R, Blincow ED, Blackbourn SJ, et al. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet 1988; ii: 1439-42.","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"705","DOI":"10.7326\/0003-4819-116-9-705","article-title":"Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomised, controlled study","volume":"116","author":"Graham, D.Y.; Lew, G.M.; Klein, P.D.; Evans, D.G.; Evans, D.J.; Saeed, Z.A.","year":"1992","unstructured":"Graham DY, Lew GM, Klein PD, Evans DG, Evans DJ, Saeed ZA, et al. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomised, controlled study. Ann Intern Med 1992; 116: 705-8.","journal-title":"Ann Intern Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/0140-6736(90)91301-P","article-title":"Cure of duodenal ulcer associated with eradication of Helicobacter pylori","volume":"335","author":"Rauws, E.A.; Tytgat, G.N.","year":"1990","unstructured":"Rauws EA, Tytgat GN. Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet 1990; 335: 1233-5.","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1007\/BF01538072","article-title":"Gastric metaplasia in duodenal bulb and Campylobacter-like organisms in development of duodenal ulcer","volume":"34","author":"Caselli, M.; Trevisani, L.; Aleotti, A.; Bovolenta, M.R.; Stabellini, G.","year":"1989","unstructured":"Caselli M, Trevisani L, Aleotti A, Bovolenta MR, Stabellini G. Gastric metaplasia in duodenal bulb and Campylobacter-like organisms in development of duodenal ulcer. Dig Dis Sci 1989; 34: 1374-8.","journal-title":"Dig Dis Sci"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1136\/gut.30.6.790","article-title":"Campylobacter pylori, duodenal ulcer, and gastric metaplasia: possible role of functional heterotopic tissue in ulcerogenesis","volume":"30","author":"Carrick, J.; Lee, A.; Hazell, S.; Ralston, M.; Daskalopoulos, G.","year":"1989","unstructured":"Carrick J, Lee A, Hazell S, Ralston M, Daskalopoulos G. Campylobacter pylori, duodenal ulcer, and gastric metaplasia: possible role of functional heterotopic tissue in ulcerogenesis. Gut 1989; 30: 790-7.","journal-title":"Gut"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/343082a0","article-title":"Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells","volume":"343","author":"Wright, N.A.; Pike, C.; Elia, G.","year":"1990","unstructured":"Wright NA, Pike C, Elia G. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature 1990; 343: 82-5.","journal-title":"Nature"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1136\/jcp.43.12.981","article-title":"Gastric epithelium in the duodenum: its association with Helicobacter pylori and inflammation","volume":"43","author":"Wyatt, J.I.; Rathbone, B.J.; Sobala, G.M.; Shallcross, T.; Heatley, R.V.; Axon, A.T.","year":"1990","unstructured":"Wyatt JI, Rathbone BJ, Sobala GM, Shallcross T, Heatley RV, Axon AT, et al. Gastric epithelium in the duodenum: its association with Helicobacter pylori and inflammation. 7 Clin Pathol 1990; 43: 981-6.","journal-title":"7 Clin Pathol"},{"key":"ref_12","first-page":"271","article-title":"Duodenal bulb biopsy findings for patients with non-ulcer dyspepsia with or without Campylobacter pylori gastritis","volume":"3","author":"Frierson, H.J.; Caldwell, S.H.; Marshall, B.J.","year":"1990","unstructured":"Frierson HJ, Caldwell SH, Marshall BJ. Duodenal bulb biopsy findings for patients with non-ulcer dyspepsia with or without Campylobacter pylori gastritis. Mod Pathol 1990; 3: 271-6.","journal-title":"Mod Pathol"},{"key":"ref_13","first-page":"16","article-title":"Chronic nonspecific duodenitis. A multiple biopsy study of the duodenal bulb in health and disease","volume":"167","author":"Kreuning, J.; Wal, A.M.; Kuiper, G.; Lindeman, J.","year":"1989","unstructured":"Kreuning J, Wal AM, Kuiper G, Lindeman J. Chronic nonspecific duodenitis. A multiple biopsy study of the duodenal bulb in health and disease. Scand J Gastroenterol Suppi 1989; 167: 16-20.","journal-title":"Scand J Gastroenterol Suppi"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1136\/gut.30.3.311","article-title":"Enhancement by tetragastrin of experimental induction of gastric epithelium in the duodenum","volume":"30","author":"Tatsuta, M.; Iishi, H.; Yamamura, H.; Yamamoto, R.; Taniguchi, H.","year":"1989","unstructured":"Tatsuta M, Iishi H, Yamamura H, Yamamoto R, Taniguchi H. Enhancement by tetragastrin of experimental induction of gastric epithelium in the duodenum. Gut 1989; 30: 311-5.","journal-title":"Gut"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1159\/000199597","article-title":"High incidence of Campylobacter-like organisms in endoscopic biopsies from patients with gastritis with or without peptic ulcer","volume":"38","author":"Fiocca, R.; Villani, L.; Turpini, F.; Turpini, R.; Solcia, E.","year":"1987","unstructured":"Fiocca R, Villani L, Turpini F, Turpini R, Solcia E. High incidence of Campylobacter-like organisms in endoscopic biopsies from patients with gastritis with or without peptic ulcer. Digestion 1987; 38: 234-44.","journal-title":"Digestion"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/path.1711620310","article-title":"Helicobacter pylori infection of gastric mucin cell metaplasia: the duodenum revisited","volume":"162","author":"Johan, G.; Offerhaus, A.; Molyvas, E.N.; Hoedemaeker, P.J.","year":"1990","unstructured":"Johan G, Offerhaus A, Molyvas EN, Hoedemaeker PJ. Helicobacter pylori infection of gastric mucin cell metaplasia: the duodenum revisited. Y Pathol 1990; 162: 239-43.","journal-title":"Y Pathol"},{"issue":"23","key":"ref_17","first-page":"93","article-title":"The role of antibiotics in Campylobacter pylori associated peptic ulcer disease. ScandJ3 Gastroenterol","volume":"1988","author":"Bayerdorffer, E.; Ottenjann, R.","unstructured":"Bayerdorffer E, Ottenjann R. The role of antibiotics in Campylobacter pylori associated peptic ulcer disease. ScandJ3 Gastroenterol Suppl 1988; 23: 93-100.","journal-title":"Suppl"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/ajcp\/90.6.711","article-title":"Prevalence of gastric metaplasia, inflammation, and Campylobacter pylori in the duodenum of members of a normal population","volume":"90","year":"1988","unstructured":"Fitzgibbons PL, Dooley CP, Cohen H, Appleman MD. Prevalence of gastric metaplasia, inflammation, and Campylobacter pylori in the duodenum of members of a normal population. Am Y Clin Pathol 1988; 90: 711-4.","journal-title":"Am Y Clin Pathol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1136\/jcp.40.8.841","article-title":"Campylobacter pyloridis and acid induced gastric metaplasia in the pathogenesis of duodenitis","volume":"40","author":"Wyatt, J.I.; Rathbone, B.J.; Dixon, M.F.; Heatley, R.V.","year":"1987","unstructured":"Wyatt JI, Rathbone BJ, Dixon MF, Heatley RV. Campylobacter pyloridis and acid induced gastric metaplasia in the pathogenesis of duodenitis. J Clin Pathol 1987; 40: 841-8.","journal-title":"J Clin Pathol"},{"key":"ref_20","first-page":"51","article-title":"Does the duodenal cell ever return to normal? A comparison between treatment with cimetidine and deNol","volume":"13","author":"Moshal, M.G.; Gregory, M.A.; Pillay, C.; Spitaels, J.M.","year":"1978","unstructured":"Moshal MG, Gregory MA, Pillay C, Spitaels JM. Does the duodenal cell ever return to normal? A comparison between treatment with cimetidine and deNol. Scand J Gastroenterol Suppl 1978; 13: 51-8.","journal-title":"Scand J Gastroenterol Suppl"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1136\/gut.34.11.1510","article-title":"Gastric metaplasia and Helicobacter pylori infection","volume":"34","author":"Noach, L.A.; Rolf, T.M.; Bosma, N.B.; Schwartz, M.P.; Oosting, J.; Rauws, E.A.J.","year":"1993","unstructured":"Noach LA, Rolf TM, Bosma NB, Schwartz MP, Oosting J, Rauws EAJ, et al. Gastric metaplasia and Helicobacter pylori infection. Gut 1993; 34: 1510-4.","journal-title":"Gut"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/path.1700400203","article-title":"The healing of artificial defects of the duodenal mucosa","volume":"40","author":"Florey, H.; Harding, H.","year":"1935","unstructured":"Florey H, Harding H. The healing of artificial defects of the duodenal mucosa. J Pathol Bacteriol 1935; 40: 211-8.","journal-title":"J Pathol Bacteriol"},{"key":"ref_23","first-page":"697","article-title":"Urea protects Helicobacter (Campylobacter) pylori from the bactericidal","volume-title":"effect of acid. Gastroenterology 1990","volume":"99","author":"Marshall, B.J.; Barrett, U.; Prakash, C.; McCallum, R.W.; Guerrant, R.L.","unstructured":"Marshall BJ, Barrett U, Prakash C, McCallum RW, Guerrant RL. Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid. Gastroenterology 1990; 99: 697-702."},{"key":"ref_24","first-page":"394","article-title":"Ablation of exaggerated meal-stimulated gastrin release in duodenal ulcer patients after clearance of Helicobacter (Campylobacter) pylori infection","volume":"85","author":"Graham, D.Y.; Opekun, A.; Lew, G.M.; Evans, D.J.; Klein, P.D.; Evans, D.G.","year":"1990","unstructured":"Graham DY, Opekun A, Lew GM, Evans DJ, Klein PD, Evans DG. Ablation of exaggerated meal-stimulated gastrin release in duodenal ulcer patients after clearance of Helicobacter (Campylobacter) pylori infection. Am J Gastroenterol 1990; 85: 394-8.","journal-title":"Am J Gastroenterol"},{"key":"ref_25","first-page":"78","article-title":"Gastric metaplasia in the duodenum and Campylobacter pylori","volume":"13","author":"Wyatt, J.I.; Rathbone, B.J.","year":"1989","unstructured":"Wyatt JI, Rathbone BJ. Gastric metaplasia in the duodenum and Campylobacter pylori. Gastroenterol Clin Biol 1989; 13: 78-82B.","journal-title":"Gastroenterol Clin Biol"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3109\/00365528809093891","article-title":"Histologic changes in the gastroduodenal mucosa after long-term medical treatment with cimetidine or parietal cell vagotomy in patients with juxtapyloric ulcer disease","volume":"23","author":"Jonsson, K.A.; Strom, M.; Bodemar, G.; Norrby, K.","year":"1988","unstructured":"Jonsson KA, Strom M, Bodemar G, Norrby K. Histologic changes in the gastroduodenal mucosa after long-term medical treatment with cimetidine or parietal cell vagotomy in patients with juxtapyloric ulcer disease. Scand Jf Gastroenterol 1988; 23: 433-41.","journal-title":"Scand Jf Gastroenterol"},{"key":"ref_27","first-page":"167","article-title":"Campylobacter pylori and duodenal ulcers: the gastrin link","volume":"1","author":"Levi, S.; Beardshall, K.; Haddad, G.; Playford, R.; Ghosh, P.; Calam, J.","year":"1989","unstructured":"Levi S, Beardshall K, Haddad G, Playford R, Ghosh P, Calam J. Campylobacter pylori and duodenal ulcers: the gastrin link. Lancet 1989; i: 1 167-8.","journal-title":"Lancet"},{"key":"ref_28","series-title":"Gut","article-title":"Quantitative study of H pylori infection density, urease activity and pathogenicity","volume":"34","author":"Khulusi, S.; Mendall, M.A.; Patel, P.; Levy, J.; Goggin, P.M.; Northfield, T.C.","year":"1993","unstructured":"Khulusi S, Mendall MA, Patel P, Levy J, Goggin PM, Northfield TC. Quantitative study of H pylori infection density, urease activity and pathogenicity [Abstract]. Gut 1993; 34: (suppl 4) S50."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/978-3-642-75315-2_35","article-title":"Differences between helicobacter associated gastritis in patients with duodenal ulcer, pyloric ulcer, other gastric ulcers and gastritis without ulcer","volume-title":"pylori gastritis and peptic ulcer","author":"Eidt, S.; Stolte, M.","year":"1990","unstructured":"Eidt S, Stolte M. Differences between helicobacter associated gastritis in patients with duodenal ulcer, pyloric ulcer, other gastric ulcers and gastritis without ulcer. In: Malfertheiner P, Ditschuneit H, eds. Helicobacter pylori gastritis and peptic ulcer. Berlin: Springer-Verlag, 1990: 228-36."}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.36.2.193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T03:22:50Z","timestamp":1601090570000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.36.2.193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,2,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/gut.36.2.193","relation":{},"ISSN":["0017-5749"],"issn-type":[{"value":"0017-5749","type":"print"}],"subject":[],"published":{"date-parts":[[1995,2,1]]}}}