{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:39:56Z","timestamp":1791488396731,"version":"4.3.4"},"reference-count":51,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1995,6]]},"abstract":"<jats:p>Exogenous fibre added to liquid meals delays gastric emptying. Its effect on solid meals is uncertain, and nothing is known of the effect on gastric emptying of fibre naturally present in food. This study therefore looked at gastric emptying of two different solid meals in eight healthy subjects and their blood glucose responses. The meals were exactly equivalent except for the total dietary fibre content (high fibre 20 g, low fibre 4 g of dietary fibre per 1000 kcal) and supplied 870 kcal (700 kcal women), 47% of which was from carbohydrates, 36% from fats, and 17% from proteins. Ultrasonography was used to measure antral diameters before the meal (basal), immediately after it (time 0), and at 30, 60, 120, 180, 240, and 300 minutes. In addition, subjects filled in a questionnaire on their feelings of hunger, epigastric fullness, and satiety before the meal and at hourly intervals after it. Basal and maximal postprandial antral sections were similar for the two meals (basal section: 283.9 (29.5) v 340.9 (44.7) mm2 for the low and the high fibre meal, NS; maximal postprandial section: 1726 (101.9) v 1593 (120.4) mm2, NS). Total gastric emptying time was significantly reduced by fibre removal (186.0 (15.6) v 231.7 (17.3) minutes after the low and the high fibre meal, p &lt; 0.05). Blood glucose was higher after the low fibre meal, and the area under the glycaemic curve significantly greater (226 (23.1) v 160 (20.0) mmol\/min\/dl-1, p &lt; 0.05). No difference was found in satiety or fullness feelings, but hunger returned more rapidly after the low fibre meal. In conclusion, fibre naturally present in food delays gastric emptying of a solid meal, reduces the glycaemic response, and delays the return of hunger.<\/jats:p>","DOI":"10.1136\/gut.36.6.825","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"825-830","source":"Crossref","is-referenced-by-count":139,"title":["Gastric emptying of a solid meal is accelerated by the removal of dietary fibre naturally present in food."],"prefix":"10.1136","volume":"36","author":[{"given":"L","family":"Benini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Castellani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Brighenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K W","family":"Heaton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M T","family":"Brentegani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M C","family":"Casiraghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Sembenini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Pellegrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Fioretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Minniti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1995,6,1]]},"reference":[{"key":"ref_1","first-page":"482","article-title":"High-fibre diets in the treatment of diabetes mellitus","volume":"88","author":"Miranda, P.M.; Horowitz, D.L.","year":"1978","unstructured":"Miranda PM, Horowitz DL. 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Gastroenterology 1986; 90","author":"Meyer, J.H.; Mayer, E.A.; Jehn, D.; Gu, Y.; Fink, A.S.; Fried, M.","unstructured":"Meyer JH, Mayer EA, Jehn D, Gu Y, Fink AS, Fried M. Gastric processing and emptying of fat. Gastroenterology 1986; 90:1176-87."},{"key":"ref_22","first-page":"1039","article-title":"Influence of fibre on postprandial intragastric juice acidity, pepsin and bile acids in healthy subjects","volume":"19","author":"Rydning, A.; Nesland, A.; Berstad, A.","year":"1984","unstructured":"Rydning A, Nesland A, Berstad A. Influence of fibre on postprandial intragastric juice acidity, pepsin and bile acids in healthy subjects. 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Hepatogastroenterology 1985; 32: 69-71.","journal-title":"Hepatogastroenterology"},{"key":"ref_25","first-page":"330","article-title":"The effect of guar gum and fiber-enriched wheat bran on gastric emptying of a semisolid meal in healthy subjects","volume":"20","author":"Rydning, A.; Berstad, A.; Berstad, T.; Hertzenberg, L.","year":"1985","unstructured":"Rydning A, Berstad A, Berstad T, Hertzenberg L. The effect of guar gum and fiber-enriched wheat bran on gastric emptying of a semisolid meal in healthy subjects. ScandJ7 Gastroenterol 1985; 20: 330-4."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0009-9260(83)80329-8","article-title":"Technetium-99m labelled bran: a new agent for measuring gastric emptying","volume":"34","author":"Sagar, S.; Grime, J.S.; Little, W.; Patten, M.; Gulliford, P.; Critchley, M.","year":"1983","unstructured":"Sagar S, Grime JS, Little W, Patten M, Gulliford P, Critchley M, et al. 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Measurement of gastric emptying time by real-time ultrasonography. Gastroenterology 1985; 89: 752-9.","journal-title":"Gastroenterology"},{"key":"ref_35","first-page":"496","article-title":"Evaluation of the use of ultrasonography in the study of liquid gastric emptying","volume":"84","author":"Marzio, L.; Giacobbe, A.; Conoscitore, P.; Facciorusso, D.; Frusciante, V.; Modoni, S.","year":"1989","unstructured":"Marzio L, Giacobbe A, Conoscitore P, Facciorusso D, Frusciante V, Modoni S. Evaluation of the use of ultrasonography in the study of liquid gastric emptying. Am Jf Gastroenterol 1989; 84: 496-500.","journal-title":"Am Jf Gastroenterol"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1136\/gut.29.1.85","article-title":"Biphasic nature of gastric emptying","volume":"29","author":"Ja, Siegel; J-L, Urbain; LP, Adler; ND, Charkes; AH, Maurer; B, Krevsky","year":"1988","unstructured":"Siegel Ja, Urbain J-L, Adler LP, Charkes ND, Maurer AH, Krevsky B, et al. 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