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Lancet 1989; i: 1164-67.","journal-title":"Lancet"},{"key":"ref_56","first-page":"86","article-title":"Controlled trial of absolute ethanol vs epinephrine as injection agent in gastroduodenal bleeding","volume":"96","author":"Chiozzini, G.; Bortoluzzi, F.; Pallini, P.; Betetto, G.; Costantini, R.; Costa, F.","year":"1989","unstructured":"Chiozzini G, Bortoluzzi F, Pallini P, Betetto G, Costantini R, Costa F et al. Controlled trial of absolute ethanol vs epinephrine as injection agent in gastroduodenal bleeding. GastroenterologSy 1989; 96: A86.","journal-title":"GastroenterologSy"},{"key":"ref_57","article-title":"Injection therapy for prevention of rebleeding from peptic ulcers with protruding vessel: which method","volume-title":"is best? Gastroenterology 1990; 98: Al","volume":"15","author":"Rutgeerts, P.; Gevers, A.M.; Hiele, M.","unstructured":"Rutgeerts P, Gevers AM, Hiele M. Injection therapy for prevention of rebleeding from peptic ulcers with protruding vessel: which method is best? Gastroenterology 1990; 98: Al 15."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0016-5107(93)70003-6","article-title":"Endoscopic injection for the arrest of peptic ulcer haemorrhage: final results of a prospective, randomised comparative trial","volume":"39","author":"Lin, H.J.; Pemg, C.L.; Lee, F.Y.","year":"1993","unstructured":"Lin HJ, Pemg CL, Lee FY. Endoscopic injection for the arrest of peptic ulcer haemorrhage: final results of a prospective, randomised comparative trial. Gastrointest Endosc 1993; 39: 15-19.","journal-title":"Gastrointest Endosc"},{"key":"ref_59","first-page":"504","article-title":"Fatal injection sclerotherapy of a bleeding peptic ulcer","volume":"37","author":"Levy, J.; Khakoo, S.; Barton, R.; Vicary, R.","year":"1991","unstructured":"Levy J, Khakoo S, Barton R, Vicary R. Fatal injection sclerotherapy of a bleeding peptic ulcer. Lancet 1991; 37: 504.","journal-title":"Lancet"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1055\/s-2007-1010728","article-title":"Extensive necrosis of gastric mucosa following injection therapy of bleeding peptic ulcer","volume":"22","author":"Loperfids, S.; Patelli, G.; La Torre, L.","year":"1990","unstructured":"Loperfids S, Patelli G, La Torre L. Extensive necrosis of gastric mucosa following injection therapy of bleeding peptic ulcer. Endoscopy 1990; 22: 285-86.","journal-title":"Endoscopy"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1055\/s-2007-1012873","article-title":"Gastric necrosis: a complication of endoscopic sclerosis for bleeding peptic ulcer","volume":"22","year":"1990","unstructured":"Chester JF, Hurley PR. Gastric necrosis: a complication of endoscopic sclerosis for bleeding peptic ulcer. Endoscopy 1990; 22: 287.","journal-title":"Endoscopy"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0016-5085(91)90579-A","article-title":"Injection of heater probe for bleeding ulcer","volume":"100","author":"Chung, S.C.S.; Leung, J.W.C.; Sung, J.Y.; Lo, K.K.; Li, A.K.C.","year":"1991","unstructured":"Chung SCS, Leung JWC, Sung JY, Lo KK, Li AKC. Injection of heater probe for bleeding ulcer. Gastroenterology 1991; 100: 33-37.","journal-title":"Gastroenterology"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0016-5107(94)70006-0","article-title":"Value of second-look endoscopy after injection therapy for bleeding peptic ulcer: a prospective and randomised trial","volume":"40","author":"Villanueva, C.; Balanzo, J.; Torras, X.; Soriano, G.; Sainz, S.; Vilardell, F.","year":"1994","unstructured":"Villanueva C, Balanzo J, Torras X, Soriano G, Sainz S, Vilardell F. Value of second-look endoscopy after injection therapy for bleeding peptic ulcer: a prospective and randomised trial. Gastrointest Endosc 1994; 40: 34-39.","journal-title":"Gastrointest Endosc"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0016-5107(91)70718-9","article-title":"A randomised comparison of multipolar electrocoagulation and injection sclerosis for the treatment of bleeding peptic ulcer","volume":"37","author":"Waring, J.P.; Sanowski, R.A.; Sawyer, R.L.; Woods, C.A.; Foutch, P.G.","year":"1991","unstructured":"Waring JP, Sanowski RA, Sawyer RL, Woods CA, Foutch PG. A randomised comparison of multipolar electrocoagulation and injection sclerosis for the treatment of bleeding peptic ulcer. Gastrointest Endosc 1991; 37: 295-98.","journal-title":"Gastrointest Endosc"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/gut.31.7.753","article-title":"Heat probe thermocoagulation and pure alcohol injection in massive peptic ulcer haemorrhage: a prospective, randomised controlled trial","volume":"31","author":"Lin, H.J.; Lee, F.Y.; Kang, W.M.; Tsai, Y.T.; Lee, S.D.; Lee, C.H.","year":"1990","unstructured":"Lin HJ, Lee FY, Kang WM, Tsai YT, Lee SD, Lee CH. Heat probe thermocoagulation and pure alcohol injection in massive peptic ulcer haemorrhage: a prospective, randomised controlled trial. 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Gastroenterologv 1990; 99: 1303-06.","journal-title":"Gastroenterologv"},{"key":"ref_68","first-page":"283","article-title":"A prospective randomised trial of heat probe thermocoagulation versus pure alcohol injection in nonvariceal peptic ulcer haemorrhage","volume":"83","author":"Lin, H.J.; Tsai, Y.T.; Lee, S.D.","year":"1988","unstructured":"Lin HJ, Tsai YT, Lee SD. A prospective randomised trial of heat probe thermocoagulation versus pure alcohol injection in nonvariceal peptic ulcer haemorrhage. Am J Gastroenterol 1988; 83: 283-86.","journal-title":"Am J Gastroenterol"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0016-5107(91)70719-0","article-title":"A randomised comparative study of laser photocoagulation, heater probe, and bipolar electrocoagulation in the treatment of actively bleeding ulcers","volume":"37","author":"Hui, W.M.; Ng, M.M.T.; Lok, A.S.F.; Lai, C.L.; Lau, Y.N.; Lam, S.K.A.","year":"1991","unstructured":"Hui WM, Ng MMT, Lok ASF, Lai CL, Lau YN, Lam SKA. A randomised comparative study of laser photocoagulation, heater probe, and bipolar electrocoagulation in the treatment of actively bleeding ulcers. Gastrointest Endosc 1991; 37: 299-304.","journal-title":"Gastrointest Endosc"},{"key":"ref_70","first-page":"27","article-title":"Epinephrine injection alone or epinephrine injection plus heat probe treatment for bleeding ulcers","volume":"40","author":"Chung, S.C.S.; Sung, J.Y.; Lai, C.W.; Ng, E.K.W.; Chan, K.L.; Yung, M.Y.","year":"1994","unstructured":"Chung SCS, Sung JY, Lai CW, Ng EKW, Chan KL, Yung MY. Epinephrine injection alone or epinephrine injection plus heat probe treatment for bleeding ulcers. Gastrointest Endosc 1994; 40: A27 1.","journal-title":"Gastrointest Endosc"},{"key":"ref_71","first-page":"42","article-title":"Prospective study of thermal coagulation (gold probe-GP) vs combination injection and thermal (Inj&Gp) treatment of high risk patients with severe ulcer of mallory weiss (MW) bleeding","volume":"40","author":"Jensen, D.M.; Kovacs, T.; Randall, G.; Smith, J.; Freeman, M.; Jutabha, R.","year":"1994","unstructured":"Jensen DM, Kovacs T, Randall G, Smith J, Freeman M, Jutabha R. Prospective study of thermal coagulation (gold probe-GP) vs combination injection and thermal (Inj&Gp) treatment of high risk patients with severe ulcer of mallory weiss (MW) bleeding. Gastrointest Endosc 1994; 40: A42.","journal-title":"Gastrointest Endosc"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1055\/s-2007-1010277","article-title":"Endoscopic hemoclip treatment for gastrointestinal bleeding","volume":"25","author":"Binmoeller, K.F.; Thonke, F.; Soehendra, N.","year":"1993","unstructured":"Binmoeller KF, Thonke F, Soehendra N, Endoscopic hemoclip treatment for gastrointestinal bleeding. Endoscopy 1993; 25: 167-70.","journal-title":"Endoscopy"},{"article-title":"Experimental studies of new mechanical methods of endoscopic haemostasis; stitching, banding, clamping and ulcer removal","author":"Swain, C.P.; Mills, T.N.; Northfield, T.C.","key":"ref_73","unstructured":"Swain CP, Mills TN, Northfield TC. Experimental studies of new mechanical methods of endoscopic haemostasis; stitching, banding, clamping and ulcer removal. Gut 1985; 26: Al 151."},{"issue":"2","key":"ref_74","article-title":"Comparison of endoscopic mechanical and injection methods of hemostais on mesenteric vessels","volume":"35","author":"Hepworth, C.C.; Kadirkamanathan, S.S.; Swain, C.P.; Gong, F.","year":"1994","unstructured":"Hepworth CC, Kadirkamanathan SS, Swain CP, Gong F. Comparison of endoscopic mechanical and injection methods of hemostais on mesenteric vessels. Gut 1994; 35 (suppl 2): A T157.","journal-title":"Gut"},{"issue":"2","key":"ref_75","article-title":"Failures of endoscopic therapy for bleeding peptic ulcer; an analysis of risk factors","volume":"35","author":"Choudari, C.P.; Palmer, K.R.","year":"1994","unstructured":"Choudari CP, Palmer KR. Failures of endoscopic therapy for bleeding peptic ulcer; an analysis of risk factors. 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