{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T08:18:17Z","timestamp":1765613897368,"version":"3.48.0"},"reference-count":14,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:p>Leiomyoma of the oesophagus, although the commonest benign oesophageal tumour, is still rare compared with malignant tumours of the oesophagus. Leiomyomas of the oesophagus are usually diagnosed on barium swallow or histological examination after section. Five cases of leiomyoma of the oesophagus are reported where diagnosis was made by the combination of barium swallow, upper gastrointestinal endoscopy, and computed tomography and all but one patient were followed up for one to four years. The endoscopic biopsy specimens were non-specific in all five patients but none showed any evidence of malignancy. None of the five patients had a history of dysphagia. This paper describes a conservative approach to medical treatment in asymptomatic oesophageal leiomyoma rather than surgical excision as commonly published. It also emphasises the importance of negative endoscopic pinch biopsy specimens and the role of computed tomography in the diagnosis of oesophageal leiomyoma.<\/jats:p>","DOI":"10.1136\/gut.37.2.288","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"288-291","source":"Crossref","is-referenced-by-count":14,"title":["Endoscopy and computed tomography in the diagnosis and follow up of oesophageal leiomyoma."],"prefix":"10.1136","volume":"37","author":[{"given":"M A","family":"Cox","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B T","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Sagar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1995,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0037-198X(81)90037-7","article-title":"Intrinsic diseases of the adult oesophagus: benign and malignant tumours","volume":"16","author":"Goldstein, H.M.; Zornoza, J.; Hopens, T.","year":"1981","unstructured":"Goldstein HM, Zornoza J, Hopens T. 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Multiple leiomyomas of the esophagus. Radiology 1974; 118: 29-34.","journal-title":"Radiology"},{"key":"ref_9","first-page":"396","article-title":"Giant leiomyoma of the oesophagus and cardia weighing more","volume":"1000","author":"Tsusuki, T.; Kakegawa, T.; Arimori, M.; Veda, M.; Watanabe, H.","year":"1971","unstructured":"Tsusuki T, Kakegawa T, Arimori M, Veda M, Watanabe H. Giant leiomyoma of the oesophagus and cardia weighing more than 1000 g. Chest 1971; 60: 396-9.","journal-title":"than"},{"key":"ref_10","first-page":"1435","article-title":"Leiomyoma of the oesophagus","volume":"47","author":"Lepore, M.; Ruggieri, M.; Caminati, A.; Capriotti, I.; Canuti, W.; Dell'Arte, R.","year":"1992","unstructured":"Lepore M, Ruggieri M, Caminati A, Capriotti I, Canuti W, Dell'Arte R, et al. Leiomyoma of the oesophagus. Minerva Chir 1992; 47: 1435-9.","journal-title":"Minerva Chir"},{"key":"ref_11","first-page":"79","article-title":"Leiomyoma of the esophagus. 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The roentgenological appearance of intramural and extramural lesions of the gastrointestinal tract in general. AmJ Roentgenol 1942; 48: 1-15.","journal-title":"AmJ Roentgenol"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0016-5107(91)70778-5","article-title":"Evaluation of submucosal upper gastrointestinal tract lesions by endoscopic ultrasound","volume":"37","author":"Boyce, G.A.; Sivak, M.V.; Rosal, T.; Classen, M.; Fleischer, D.E.; Boyce, H.W.","year":"1991","unstructured":"Boyce GA, Sivak MV, Rosal T, Classen M, Fleischer DE, Boyce HW, et al. Evaluation of submucosal upper gastrointestinal tract lesions by endoscopic ultrasound. 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