{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T12:16:25Z","timestamp":1789820185177,"version":"4.0.1"},"reference-count":30,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"accepted":{"date-parts":[[1998,1,19]]},"published-print":{"date-parts":[[1998,7,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background\/Aims<\/jats:italic>\n                    \u2014Chronic intestinal pseudo-obstruction (CIPO) reflects a dysfunction of the visceral smooth muscle or the enteric nervous system. Gastrointestinal manifestations are common in systemic lupus erythematosus (SLE) but CIPO has not been reported. Features of CIPO are reported in five patients with SLE.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods<\/jats:italic>\n                    \u2014From 1988 to 1993, five patients with SLE or SLE-like syndrome were hospitalised for gastrointestinal manometric studies. CIPO was the onset feature in two cases. Antroduodenal manometry (three hours fasting, two hours fed) was performed in all patients, and oesophageal manometry in four.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    \u2014Intestinal hypomotility associated with reduced bladder capacity and bilateral ureteral distension was found in four patients and aperistalsis of the oesophagus in three. Treatment, which consisted of high dose corticosteroids, parenteral nutrition, promotility agents, and antibiotics, led to remission of both CIPO and urinary abnormalities in all cases. Antroduodenal manometry performed in two patients after remission showed increased intestinal motility. One patient died, and postmortem examination showed intestinal vasculitis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    \u2014CIPO in SLE is a life threatening situation that can be reversed by treatment. It may be: (\n                    <jats:italic>a<\/jats:italic>\n                    ) a complication or onset feature of the disease; (\n                    <jats:italic>b<\/jats:italic>\n                    ) secondary to smooth muscle involvement; (\n                    <jats:italic>c<\/jats:italic>\n                    ) associated with ureteral and vesical involvement; (\n                    <jats:italic>d<\/jats:italic>\n                    ) the result of intestinal vasculitis.\n                  <\/jats:p>","DOI":"10.1136\/gut.43.1.117","type":"journal-article","created":{"date-parts":[[2010,6,30]],"date-time":"2010-06-30T12:46:12Z","timestamp":1277901972000},"page":"117-122","source":"Crossref","is-referenced-by-count":77,"title":["Chronic intestinal pseudo-obstruction in systemic lupus erythematosus"],"prefix":"10.1136","volume":"43","author":[{"given":"G","family":"Perlemuter","sequence":"first","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Chaussade","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Wechsler","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Cacoub","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Dapoigny","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Kahan","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Godeau","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital Cochin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Couturier","sequence":"additional","affiliation":[{"name":"aService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France, \n\nbService de M\u00e9decine interne, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, 83 boulevard de l\u2019H\u00f4pital, 75651 Paris Cedex 13, \n\ncService d\u2019H\u00e9patogastro- ent\u00e9rologie, H\u00f4pital H\u00f4tel-Dieu, boulevard L\u00e9on-Malfreyt, 63003 Clermont-Ferrand Cedex, France, \n\ndService de Rhumatologie, H\u00f4pital 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