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These changes disappeared completely when the patient was put on a gluten-free diet.<\/jats:p>","DOI":"10.1136\/gut.5.4.304","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"304-308","source":"Crossref","is-referenced-by-count":9,"title":["Sideroblastic anaemia in adult coeliac disease"],"prefix":"10.1136","volume":"5","author":[{"given":"A. M.","family":"Dawson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. D.","family":"Holdsworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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Invest"},{"key":"ref_19","first-page":"1157","article-title":"Distribution of pyridoxal, pyridoxamine, and pyridoxine in some natural products","volume":"176","author":"Rabinowitz, J.C.; Snell, E.E.","year":"1948","unstructured":"Rabinowitz, J. C. and Snell, E. E. (1948). Distribution of pyridoxal, pyridoxamine, and pyridoxine in some natural products. J. biol. Chem., 176, 1157-1167.","journal-title":"J. biol. Chem"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3181\/00379727-88-21576","article-title":"Xanthurenic acid excretion studies in diabetes with and without retinopathy","volume":"88","author":"Rosen, D.A.; Maengwyn-Davies, G.D.; Becker, B.; Stone, H.H.; Friedenwald, J.S.","year":"1955","unstructured":"Rosen, D. A., Maengwyn-Davies, G. D., Becker, B., Stone, H. H., and Friedenwald, J. S. (1955). Xanthurenic acid excretion studies in diabetes with and without retinopathy. Proc. Soc. exp. Biol. (N. Y.), 88, 321-323.","journal-title":"Proc. Soc. exp. 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