{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:11:11Z","timestamp":1791108671975,"version":"4.1.0"},"reference-count":42,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Commitment to food safety is evidenced by high profile governmental initiatives around the globe. To measure progress towards targets, policy makers need to know the baseline from which they started.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aim:<\/jats:bold>\n                    To describe the burden (mortality, morbidity, new presentations to general practice, hospital admissions, and hospital occupancy) and trends of indigenous foodborne disease (IFD) in England and Wales between 1992 and 2000.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Routinely available surveillance data, special survey data, and hospital episode statistics were collated and arithmetic employed to estimate the burden and trends of IFD in England and Wales. Adjustments were made for underascertainment of disease through national surveillance and for foreign travel. The final estimates were compared with those from the USA.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    In 1995 there were an estimated 2 365 909 cases, 21 138 hospital admissions, and 718 deaths in England and Wales due to IFD. By 2000 this had fallen to 1 338 772 cases, 20 759 hospital admissions, and 480 deaths. In terms of disease burden the most important pathogens were campylobacters, salmonellas,\n                    <jats:italic>Clostridium perfringens<\/jats:italic>\n                    , verocytotoxin producing\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    (VTEC) O157, and\n                    <jats:italic>Listeria monocytogenes<\/jats:italic>\n                    . The ratio of food related illness in the USA to IFD in England and Wales in 2000 was 57:1. Taking into account population rates, this ratio fell to 11:1 and converged when aetiology and disease severity were considered.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Reducing IFD in England and Wales means tackling campylobacter. Lowering mortality rates however also requires better control and prevention of salmonellas,\n                    <jats:italic>Cl perfringens<\/jats:italic>\n                    ,\n                    <jats:italic>L monocytogenes<\/jats:italic>\n                    , and VTEC O157.\n                  <\/jats:p>","DOI":"10.1136\/gut.51.6.832","type":"journal-article","created":{"date-parts":[[2002,11,11]],"date-time":"2002-11-11T15:41:40Z","timestamp":1037029300000},"page":"832-841","source":"Crossref","is-referenced-by-count":344,"title":["Trends in indigenous foodborne disease and deaths, England and Wales: 1992 to 2000"],"prefix":"10.1136","volume":"51","author":[{"given":"G K","family":"Adak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S M","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S J","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2002,12,1]]},"reference":[{"key":"2025121311111228000_51.6.832.1","unstructured":"Food Standards Agency. 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Available at <http:\/\/www.doh.gov.uk\/hes\/>."},{"key":"2025121311111228000_51.6.832.12","unstructured":"National Statistics Population Estimates Unit. Estimated resident population mid-1995 of England and Wales. London: National Statistics."},{"key":"2025121311111228000_51.6.832.13","unstructured":"Foods Standards Agency. A report of the study of infectious intestinal disease in England. London: The Stationery Office, 2000."},{"key":"2025121311111228000_51.6.832.14","unstructured":"CDSC. Campylobacter sentinel surveillance scheme. Commun Dis Rep CDR Wkly (serial online) 2001 (cited 30 August 2001); 11 (23). Available at <www.phls.co.uk\/publications\/CDR\/PDFfiles\/2001\/cdr2301.pdf>."},{"key":"2025121311111228000_51.6.832.15","first-page":"188","volume":"4","year":"2001","journal-title":"Commun Dis Public Health"},{"key":"2025121311111228000_51.6.832.16","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.3201\/eid0706.010626","volume":"7","year":"2001","journal-title":"Emerg Infect Dis"},{"key":"2025121311111228000_51.6.832.17","doi-asserted-by":"crossref","unstructured":"O\u2019Brien SJ, Adak GK, Lynn R, et al. Synergy between clinical and laboratory surveillance for describing the epidemiology of VTEC O157 in the United Kingdom. 4th International Symposium and Workshop on Shiga Toxin (Verocytotoxin)-Producing Escherichia coli Infections. Kyoto, Japan, 2000.","DOI":"10.2807\/esw.04.46.01491-en"},{"key":"2025121311111228000_51.6.832.18","unstructured":"Lorber B. Listeria monocytogenes. In: Mandell GL, Bennett JE, Dolin R, eds. 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