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A correlation has been shown between variation and intensity of staining and histologically verified stages of dysplasia or cancer. Magnification endoscopy and chromoscopy improve the detection of colonic non-polypoid lesions associated with neoplasia and carcinoma. Pitt pattern analysis enables the distinction of non-neoplastic non-polypoid lesions (type I and II) from neoplastic type non-polypoid lesions (type III-V) with great accuracy. It is certain that \u201cold fashioned\u201d chromoscopy combined with advanced endoscopic technology carry a great diagnostic potential and should be further put to the test for use in daily clinical practice.<\/jats:p>","DOI":"10.1136\/gut.52.suppl_4.iv7","type":"journal-article","created":{"date-parts":[[2003,5,13]],"date-time":"2003-05-13T15:33:45Z","timestamp":1052840025000},"page":"iv7-iv11","source":"Crossref","is-referenced-by-count":54,"title":["Magnification endoscopy, high resolution endoscopy, and chromoscopy; towards a better optical diagnosis"],"prefix":"10.1136","volume":"52","author":[{"given":"M 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