{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:34:07Z","timestamp":1791045247350,"version":"4.1.0"},"reference-count":25,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"accepted":{"date-parts":[[2000,12,19]]},"published-print":{"date-parts":[[2001,4,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To examine the influence of socioeconomic deprivation on case fatality following acute myocardial infarction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>DESIGN<\/jats:title>\n                  <jats:p>Prospective cohort observational study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>SETTING<\/jats:title>\n                  <jats:p>General hospital.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>PATIENTS<\/jats:title>\n                  <jats:p>1417 white and south Asian patients admitted with acute myocardial infarction between January 1988 and December 1996, and classified by the Carstairs socioeconomic deprivation score of the enumeration district of residence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>MAIN OUTCOME MEASURES<\/jats:title>\n                  <jats:p>30 day and one year survival.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>There was little variation across deprivation groups in age, sex, or smoking status, though a higher proportion of patients from more deprived enumeration districts were diabetic and of south Asian origin, and a higher proportion of them developed Q wave infarction and left ventricular failure. There was no appreciable variation in clinical treatment with deprivation. Patients from more deprived enumeration districts had a higher risk of recurrent ischaemic events (death, recurrent myocardial infarction, or unstable angina) over the first 30 days: event free survival (95% confidence interval (CI)) of the most deprived quartile was 0.79 (95% CI 0.74 to 0.83) compared with 0.85 (95% CI 0.80 to 0.88) in the least deprived quartile. The unadjusted hazard ratio corresponding to an increase from the 5th to 95th centile of the deprivation distribution was 1.54 (95% CI 1.02 to 2.32), and 1.59 (95% CI 1.03 to 2.44) after adjustment for age, sex, racial group, diabetes, acute treatment with thrombolysis and aspirin, and left ventricular failure. Survival from 30 days to one year, however, did not show a socioeconomic gradient (hazard ratio adjusted for the same variables was 1.07 (95% CI 0.68 to 1.70)).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>In patients hospitalised with acute myocardial infarction, there is a strong association between early recurrent ischaemic events and socioeconomic deprivation that is not accounted for by clinical presentation or treatment. This association appears to be attenuated over time.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/heart.85.4.390","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T06:37:59Z","timestamp":1027751879000},"page":"390-394","source":"Crossref","is-referenced-by-count":50,"title":["Socioeconomic differentials in recurrent ischaemia and mortality after acute myocardial infarction"],"prefix":"10.1136","volume":"85","author":[{"given":"K","family":"Barakat","sequence":"first","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Stevenson","sequence":"additional","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Suliman","sequence":"additional","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Ranjadayalan","sequence":"additional","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A D","family":"Timmis","sequence":"additional","affiliation":[{"name":"aDepartment of Cardiology, Barts and The London NHS Trust (London Chest Hospital), Bonner Road, London E2 9JX, UK, \n\nbEnvironmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, \n\ncNewham Healthcare Trust, London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2001,4,1]]},"reference":[{"key":"2025092012464847000_85.4.390.1","unstructured":"Carstairs V Morris R (1991) Deprivation and health in Scotland. (Aberdeen University Press, Aberdeen)."},{"key":"2025092012464847000_85.4.390.2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.44.4.265"},{"key":"2025092012464847000_85.4.390.3","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1992.00400230067011"},{"key":"2025092012464847000_85.4.390.4","doi-asserted-by":"crossref","first-page":"178","DOI":"10.5271\/sjweh.1590","article-title":"Differences in the incidence of myocardial infarction among occupational groups.","volume":"18","author":"Hammar","year":"1992","journal-title":"Scand J Work Environ Health"},{"key":"2025092012464847000_85.4.390.5","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.64.5.295"},{"key":"2025092012464847000_85.4.390.6","doi-asserted-by":"publisher","DOI":"10.1136\/jech.34.1.48"},{"key":"2025092012464847000_85.4.390.7","first-page":"711","article-title":"Mortality and social class in New Zealand II: male mortality by major disease groupings.","volume":"96","author":"Pearce","year":"1983","journal-title":"NZ Med J"},{"key":"2025092012464847000_85.4.390.8","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/S0140-6736(84)92337-7","article-title":"Inequalities in death: specific explanations of a general pattern.","volume":"i","author":"Marmot","year":"1984","journal-title":"Lancet"},{"key":"2025092012464847000_85.4.390.9","first-page":"1497","article-title":"Coronary heart disease and mortality among men from different occupational classes in Sweden.","volume":"297","author":"Rosengren","year":"1988","journal-title":"Br Heart J"},{"key":"2025092012464847000_85.4.390.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)92064-1"},{"key":"2025092012464847000_85.4.390.11","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1093\/oxfordjournals.eurheartj.a014743","article-title":"Are there socio-economic differences in survival after acute myocardial infarction?","volume":"17","author":"Wilhelmsen","year":"1996","journal-title":"Eur Heart J"},{"key":"2025092012464847000_85.4.390.12","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1056\/NEJM197807132990202","article-title":"Relation of education to sudden death after myocardial infarction.","volume":"299","author":"Weinblatt","year":"1978","journal-title":"N Engl J Med"},{"key":"2025092012464847000_85.4.390.13","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(93)90568-W"},{"key":"2025092012464847000_85.4.390.14","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.76.1.70"},{"key":"2025092012464847000_85.4.390.15","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.314.7080.541"},{"key":"2025092012464847000_85.4.390.16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1136\/bmj.307.6900.349","article-title":"Short and long term prognosis of acute myocardial infarction since introduction of thrombolytic therapy.","volume":"307","author":"Stevenson","year":"1993","journal-title":"BMJ"},{"key":"2025092012464847000_85.4.390.17","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780040112"},{"key":"2025092012464847000_85.4.390.18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7042.1330"},{"key":"2025092012464847000_85.4.390.19","unstructured":"Gibson RS (1996) Non-Q-wave myocadial infarction. in Atherosclerosis and coronary artery disease. eds Fuster V Ross R Topol EJ (Lippincott Raven, Philadelphia), p 1097."},{"key":"2025092012464847000_85.4.390.20","doi-asserted-by":"crossref","unstructured":"Anon (1999) Health in the East End: annual public health report 1998\/99. (East London and The City Health Authority, London).","DOI":"10.1093\/phr\/114.2.99"},{"key":"2025092012464847000_85.4.390.21","doi-asserted-by":"crossref","unstructured":"Antman EM Rutherford JD (1986) Coronary care medicine. (Martinus Nijhoff, Boston), p 20.","DOI":"10.1007\/978-1-4613-2303-7"},{"key":"2025092012464847000_85.4.390.22","unstructured":"Braunwald E. Heart disease: a textbook of cardiovascular medicine. Philadelphia: WB Saunders."},{"key":"2025092012464847000_85.4.390.23","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(83)90174-3"},{"key":"2025092012464847000_85.4.390.24","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1177\/003693309504000402","article-title":"Cardiorespiratory and all cause mortality in men and women in urban Scotland; 15 year follow up.","volume":"40","author":"Hawthorne","year":"1995","journal-title":"Scott Med J"},{"key":"2025092012464847000_85.4.390.25","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03480040107040"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heart.85.4.390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:46:54Z","timestamp":1758397614000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heart.85.4.390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4,1]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2001,4,1]]},"published-print":{"date-parts":[[2001,4,1]]}},"alternative-id":["10.1136\/heart.85.4.390"],"URL":"https:\/\/doi.org\/10.1136\/heart.85.4.390","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4,1]]}}}