{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:05:19Z","timestamp":1791104719440,"version":"4.1.0"},"reference-count":18,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"accepted":{"date-parts":[[2001,5,2]]},"published-print":{"date-parts":[[2001,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Radiofrequency ablation of tissues in pulmonary veins can eliminate paroxysmal atrial fibrillation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To explore the characteristics of normal pulmonary veins so as to provide more information relevant to radiofrequency ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>20 structurally normal heart specimens were examined grossly. Histological sections were made from 65 pulmonary veins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The longest myocardial sleeves were found in the superior veins. The sleeves were thickest at the venoatrial junction in the left superior pulmonary veins. For the superior veins, the sleeves were thickest along the inferior walls and thinnest superiorly. The sleeves were composed mainly of circularly or spirally oriented bundles of myocytes with additional bundles that were longitudinally or obliquely oriented, sometimes forming mesh-like arrangements. Fibrotic changes estimated at between 5% and 70% across three transverse sections were seen in 17 veins that were from individuals aged 30 to 72 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The myocardial architecture in normal pulmonary veins is highly variable. The complex arrangement, stretch, and increase in fibrosis may produce greater non-uniform anisotropic properties.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/heart.86.3.265","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T06:37:59Z","timestamp":1027751879000},"page":"265-270","source":"Crossref","is-referenced-by-count":365,"title":["Architecture of the pulmonary veins: relevance to radiofrequency ablation"],"prefix":"10.1136","volume":"86","author":[{"given":"S Y","family":"Ho","sequence":"first","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J A","family":"Cabrera","sequence":"additional","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V H","family":"Tran","sequence":"additional","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Farr\u00e9","sequence":"additional","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R H","family":"Anderson","sequence":"additional","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"S\u00e1nchez-Quintana","sequence":"additional","affiliation":[{"name":"aNational Heart and Lung Institute, Imperial College, Royal Brompton and Harefield NHS Trust, Dovehouse Street, London SW3 6LY, UK, \n\nbFundaci\u00f3n Jimenez D\u00edaz, Universidad Aut\u00f3noma de Madrid, Spain, \n\ncInstitute of Child Health, University College, London WC1, UK, \n\ndUniversidad de Extremadura, Departamento de Anatom\u00eda Humana, Facultad de Medicina, Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2001,9,1]]},"reference":[{"key":"2025092005015411000_86.3.265.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"2025092005015411000_86.3.265.2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.3.572"},{"key":"2025092005015411000_86.3.265.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1999.tb00654.x"},{"key":"2025092005015411000_86.3.265.4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1023\/A:1009857926782","article-title":"Atrial fibrillation: role of arrhythmic foci.","volume":"4","author":"Ja\u00efs","year":"2000","journal-title":"J Intervent Cardiol 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Anat"},{"key":"2025092005015411000_86.3.265.12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2000.tb00727.x"},{"key":"2025092005015411000_86.3.265.13","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.11.1274"},{"key":"2025092005015411000_86.3.265.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1996.tb00596.x"},{"key":"2025092005015411000_86.3.265.15","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1540-8167.2000.tb00003.x","article-title":"Dependence of electrogram duration in right posteroseptal atrium and atrium\u2013pulmonary vein junction on pacing site: mechanism and implications regarding atrioventricular nodal reentry tachycardia and paroxysmal atrial fibrillation.","volume":"11","author":"Chen","year":"2000","journal-title":"J Cardiovasc 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Its form and function in disease. (Churchill Livingstone, Edinburgh), p 7."}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heart.86.3.265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T12:02:02Z","timestamp":1758369722000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heart.86.3.265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9,1]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2001,9,1]]},"published-print":{"date-parts":[[2001,9,1]]}},"alternative-id":["10.1136\/heart.86.3.265"],"URL":"https:\/\/doi.org\/10.1136\/heart.86.3.265","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9,1]]}}}