{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T21:41:32Z","timestamp":1760737292784,"version":"build-2065373602"},"reference-count":25,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:p>\n                  <jats:bold>Background:<\/jats:bold> The recently introduced automated cardiac flow measurement (ACM) technique provides a quick and an accurate automated calculation of stroke volume and cardiac output. This is obtained by spatio-temporal integration of digital Doppler velocity profile data.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To evaluate the use of the ACM method in the non-invasive assessment of aortic regurgitant volume and per cent regurgitant fraction (%RF) in patients with aortic regurgitation.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methods:<\/jats:bold> Aortic outflow volume and mitral inflow volume were calculated by the ACM method in 22 patients with isolated aortic regurgitation. Aortic regurgitant volume and %RF were calculated using the following equations: aortic regurgitant volume = [aortic outflow volume] \u2212 [mitral inflow volume]; %RF = [aortic regurgitant volume]\/[aortic outflow volume] \u00d7 100. The results were compared with those obtained using pulsed Doppler cross sectional echocardiography (PD-2D).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> Aortic regurgitant volumes measured by the ACM method showed a good correlation with the PD-2D measurements (<jats:italic>r<\/jats:italic> = 0.95, y = 0.9x + 3.9, SEE = 8.6 ml); the mean (SD) difference between the two methods was \u22121.5 (8.5) ml. %RF estimated by the ACM method also correlated well with the values obtained by the PD-2D method (<jats:italic>r<\/jats:italic> = 0.91, y = 0.9x + 4.9, SEE = 6.0%); the mean difference between the two methods was \u22121.5 (6.0)%. Total time required for aortic regurgitant volume (for one cardiac cycle) by the ACM method was significantly shorter than by the PD-2D method (130 (16) <jats:italic>v<\/jats:italic> 230 (32) s, p &lt; 0.01).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> The newly developed the ACM method is quick and accurate in the automated assessment of aortic regurgitant volume and per cent regurgitant fraction in patients with isolated aortic regurgitation.<\/jats:p>","DOI":"10.1136\/heart.88.5.481","type":"journal-article","created":{"date-parts":[[2002,10,15]],"date-time":"2002-10-15T14:02:42Z","timestamp":1034690562000},"page":"481-484","source":"Crossref","is-referenced-by-count":4,"title":["Automated quantification of aortic regurgitant volume and regurgitant fraction using the digital colour Doppler velocity profile integration method in patients with aortic 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