{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:27:52Z","timestamp":1790738872283,"version":"4.1.0"},"reference-count":19,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To assess long term mortality and identify factors associated with the development of permanent atrial fibrillation after atrioventricular (AV) node ablation for drug refractory paroxysmal atrial fibrillation.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Design:<\/jats:bold> Retrospective cohort study.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Setting:<\/jats:bold> UK tertiary centre teaching hospital.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Patients:<\/jats:bold> Patients admitted to the University Hospital Birmingham between January 1995 and December 2000.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Interventions:<\/jats:bold> AV node ablation and dual chamber mode switching pacing.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Main outcome measures:<\/jats:bold> Long term mortality and predictors of permanent atrial fibrillation, assessed through Kaplan-Meier curves and logistic regression.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> 114 patients (1995\u20132000) were included: age (mean (SD)), 65 (9) years; 55 (48%) male; left atrial diameter 4 (1) cm; left ventricular end diastolic diameter 5 (1) cm; ejection fraction 54 (17)%. Indications for AV node ablation were paroxysmal atrial fibrillation in 95 (83%) and paroxysmal atrial fibrillation\/flutter in 19 (17%). The survival curve showed a low overall mortality after 72 months (10.5%). Fifty two per cent of patients progressed to permanent atrial fibrillation within 72 months. There was no difference in progression to permanency between paroxysmal atrial fibrillation and paroxysmal atrial fibrillation\/flutter (log rank 0.06, p = 0.8). Logistic regression did not show any association between the variables collected and the development of permanent atrial fibrillation, although age over 80 years showed a trend (p = 0.07).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> Ablate and pace is associated with a low overall mortality. No predictors of permanent atrial fibrillation were identified, but 48% of patients were still in sinus rhythm at 72 months. These results support the use of dual chamber pacing for paroxysmal atrial fibrillation patients after ablate and pace.<\/jats:p>","DOI":"10.1136\/heart.89.9.1035","type":"journal-article","created":{"date-parts":[[2003,8,15]],"date-time":"2003-08-15T15:44:37Z","timestamp":1060962277000},"page":"1035-1038","source":"Crossref","is-referenced-by-count":32,"title":["Ablate and pace revisited: long term survival and predictors of permanent atrial fibrillation"],"prefix":"10.1136","volume":"89","author":[{"given":"A","family":"Queiroga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H J","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Clune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M D","family":"Gammage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2003,8,15]]},"reference":[{"key":"2025100703505682000_89.9.1035.1","first-page":"2","volume":"82","year":"1998","journal-title":"Am J Cardiol"},{"key":"2025100703505682000_89.9.1035.2","first-page":"200","volume":"67","year":"1962","journal-title":"Am Heart J"},{"key":"2025100703505682000_89.9.1035.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1995.tb04738.x"},{"key":"2025100703505682000_89.9.1035.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.8.2617"},{"key":"2025100703505682000_89.9.1035.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.12.1587"},{"key":"2025100703505682000_89.9.1035.6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1136\/hrt.79.6.543","volume":"79","year":"1998","journal-title":"Heart"},{"key":"2025100703505682000_89.9.1035.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330070039027"},{"key":"2025100703505682000_89.9.1035.8","doi-asserted-by":"crossref","first-page":"B31","DOI":"10.1016\/eupace\/2.Supplement_1.A31-c","volume":"2","year":"2001","journal-title":"Europace"},{"key":"2025100703505682000_89.9.1035.9","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/hrt.79.6.548","volume":"79","year":"1998","journal-title":"Heart"},{"key":"2025100703505682000_89.9.1035.10","doi-asserted-by":"publisher","DOI":"10.1053\/eupc.1998.0008"},{"key":"2025100703505682000_89.9.1035.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(96)00605-4"},{"key":"2025100703505682000_89.9.1035.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1954"},{"key":"2025100703505682000_89.9.1035.13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104053441403"},{"key":"2025100703505682000_89.9.1035.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.10.1138"},{"key":"2025100703505682000_89.9.1035.15","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90003-6"},{"key":"2025100703505682000_89.9.1035.16","doi-asserted-by":"publisher","DOI":"10.4065\/75.8.790"},{"key":"2025100703505682000_89.9.1035.17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1983.tb05295.x"},{"key":"2025100703505682000_89.9.1035.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00608-2"},{"key":"2025100703505682000_89.9.1035.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00610-0"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heart.89.9.1035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T10:51:04Z","timestamp":1759834264000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heart.89.9.1035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8,15]]},"references-count":19,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2003,8,15]]},"published-print":{"date-parts":[[2003,9]]}},"alternative-id":["10.1136\/heart.89.9.1035"],"URL":"https:\/\/doi.org\/10.1136\/heart.89.9.1035","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8,15]]}}}