{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:21:29Z","timestamp":1790043689746,"version":"4.0.1"},"reference-count":29,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    To evaluate the time to onset and the predictors of atrial fibrillation (AF) during long term follow up of patients with typical atrial flutter (AFL) treated with transisthmic ablation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:<\/jats:bold>\n                    Prospective multicentre study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods and results:<\/jats:bold>\n                    383 patients (75.4% men, mean (SD) age 61.7 (11.1) years) who underwent transisthmic ablation for typical AFL were investigated. In 239 patients (62.4%) AF was present before ablation. Ablation proved successful in 367 patients (95.8%). During a mean (SD) follow up of 20.5 (12.4) months, 41.5% of patients reported AF. The cumulative probability of postablation AF increased continuously as time passed: it was 22% at six months, 36% at one year, 50% at two years, 58% at three years, and 63% at four years.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    AF occurred in a large proportion of patients after transisthmic catheter ablation of typical AFL. The occurrence of AF was progressive during follow up. Preablation AF, age &lt; 65 years, and left atrial size &gt; 50 mm are associated with postablation AF occurrence.\n                  <\/jats:p>","DOI":"10.1136\/heart.90.1.59","type":"journal-article","created":{"date-parts":[[2003,12,15]],"date-time":"2003-12-15T18:08:03Z","timestamp":1071511683000},"page":"59-63","source":"Crossref","is-referenced-by-count":71,"title":["Long term follow up of radiofrequency catheter ablation of atrial flutter: clinical course and predictors of atrial fibrillation 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