{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:00:59Z","timestamp":1787497259646,"version":"build-2736575974"},"reference-count":32,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    To evaluate long term results and independent predictors of outcome of aortic valvoplasty.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:<\/jats:bold>\n                    Retrospective follow up study. Independent predictors of outcome identified by multiple logistic regression.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Setting:<\/jats:bold>\n                    Tertiary referral centre.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Patients:<\/jats:bold>\n                    269 consecutive patients treated at the median age of 8 months (0\u201323 years): 80 (30%) under 4 weeks, 59 (22%) between 4 weeks and 1 year, and 130 (48%) over 1 year. The follow up period was up to 14.8 years (median 5.3, in survivors 6.4 years).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Interventions:<\/jats:bold>\n                    Percutaneous balloon valvoplasty with mean (SD) balloon to annulus ratio 0.97 (0.08).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Main outcome measures:<\/jats:bold>\n                    Restenosis \u2a7e 70 mm Hg, grade 3 aortic insufficiency, cusps disruption, surgery, death, and valvoplasty failure (significant restenosis or insufficiency or surgery or death).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    The mortality rate was 10.4% (n \u200a=\u200a 28), the restenosis rate was 16.7% (n\u200a=\u200a45), significant insufficiency developed in 22.3% (n\u200a=\u200a60), surgery was needed in 20.1% (n\u200a=\u200a54), and \u201cvalvoplasty failure\u201d occurred in 41.6% (n \u200a=\u200a 112) patients. Mean (SEM) survival probability 14.4 years after the procedure was 0.89 (0.02) and mean (SEM) probability of surgery-free survival was 0.50 (0.08). The independent predictors were as follows. For restenosis: small aortic annulus; for cusp disruption: large aortic annulus; for insufficiency: bicuspid aortic valve; for need for surgery: bicuspid aortic valve; for death: small aortic annulus, low left ventricular shortening fraction, and low sequential number of the valvoplasty; and for valvoplasty failure: small aortic annulus, bicuspid aortic valve, and high grade of mitral insufficiency.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Independent predictors of unfavourable outcome are small aortic annulus, bicuspid aortic valve, poor function of left ventricle or mitral valve, and limited operator experience.\n                  <\/jats:p>","DOI":"10.1136\/heart.90.1.70","type":"journal-article","created":{"date-parts":[[2003,12,15]],"date-time":"2003-12-15T18:08:03Z","timestamp":1071511683000},"page":"70-76","source":"Crossref","is-referenced-by-count":87,"title":["Long term results of 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