{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T22:09:50Z","timestamp":1769119790747,"version":"3.49.0"},"reference-count":28,"publisher":"BMJ","issue":"13","funder":[{"DOI":"10.13039\/501100005951","name":"Honjo International Scholarship Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005951","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[2016,12,29]]},"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Obesity and stable angina pectoris (SAP) are important public health problems in the USA. However, little is known about whether weight reduction affects the rate of SAP-related morbidities. This study was designed to test the hypothesis that bariatric surgery is associated with a lower rate of hospitalisations for SAP in obese adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed a self-controlled case series study of obese adults with SAP who underwent bariatric surgery using a population-based inpatient database in three states (California, Florida and Nebraska) from 2005 to 2011. The primary outcome was hospitalisation for SAP. We used conditional logistic regression to compare the rate of the outcome event during sequential 12-month periods, using presurgery months 13\u201324 as a reference period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Our sample consisted of 953 patients with SAP who underwent bariatric surgery. The median age was 57 years, 51% were women, and 78% were non-Hispanic white. During the reference period, 25.3% (95%CI, 22.5% to 28.1%) had a hospitalisation for SAP. The rate remained stable in the subsequent 12-month presurgery period (adjusted OR (aOR) 0.84 (95% CI, 0.69 to 1.02); p=0.07). In the first 12-month period after bariatric surgery, we observed a significantly lower rate (9.1% (95% CI, 7.3% to 11.0%); aOR 0.33 (95% CI, 0.26 to 0.43); p&lt;0.0001). Similarly, the rate remained significantly lower in the subsequent 13\u201324 months after bariatric surgery (8.7% (95% CI, 6.9% to 10.5%); aOR 0.31 (95% CI, 0.24 to 0.41); p&lt;0.0001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In this population-based study of obese adults with SAP, we found that the rate of hospitalisations for SAP was lower by two-thirds after bariatric surgery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/heartjnl-2016-310757","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T20:50:12Z","timestamp":1487278212000},"page":"1009-1014","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Association between bariatric surgery and rate of hospitalisations for stable angina pectoris in obese adults"],"prefix":"10.1136","volume":"103","author":[{"given":"Yuichi J","family":"Shimada","sequence":"first","affiliation":[{"name":"Department of Medicine, Cardiology Division, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Tsugawa","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyasu","family":"Iso","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, Public Health, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David FM","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,2,16]]},"reference":[{"key":"2025091922572772000_103.13.1009.1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000350"},{"key":"2025091922572772000_103.13.1009.2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.609990"},{"key":"2025091922572772000_103.13.1009.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6458"},{"key":"2025091922572772000_103.13.1009.4","unstructured":"Libby P , et al . The vascular biology of atherosclerosis. In: Mann D , Zipes D , Libby P , eds. Braunwald's heart disease: a textbook of cardiovascular medicine. Philadelphia: BMJ Publishing Group, 2014:873."},{"key":"2025091922572772000_103.13.1009.5","unstructured":"Morrow DA , Boden WE , et al . Stable ischemic heart disease. In: Mann DL , Zipes DP , Libby P , eds. Braunwald's heart disease: a textbook of cardiovascular medicine. Philadelphia: BMJ Publishing Group, 2014:1182."},{"key":"2025091922572772000_103.13.1009.6","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/sj.ejcn.1601449","article-title":"Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris","volume":"56","author":"Hankey","year":"2002","journal-title":"Eur J Clin Nutr"},{"key":"2025091922572772000_103.13.1009.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1212914"},{"key":"2025091922572772000_103.13.1009.8","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f5934","article-title":"Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials","volume":"347","author":"Gloy","year":"2013","journal-title":"BMJ"},{"key":"2025091922572772000_103.13.1009.9","unstructured":"Overview of the state inpatient databases (SID). Healthcare cost and utilization project. http:\/\/www.hcup-us.ahrq.gov\/sidoverview.jsp. (accessed 23 Dec 2016)."},{"key":"2025091922572772000_103.13.1009.10","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2302"},{"key":"2025091922572772000_103.13.1009.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.12.016"},{"key":"2025091922572772000_103.13.1009.12","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jaci.2014.12.1931","article-title":"Risk of an asthma exacerbation after bariatric surgery in adults","volume":"136","author":"Hasegawa","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"2025091922572772000_103.13.1009.13","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-013-0957-4"},{"key":"2025091922572772000_103.13.1009.14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012485"},{"key":"2025091922572772000_103.13.1009.15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1914"},{"key":"2025091922572772000_103.13.1009.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.09.940"},{"key":"2025091922572772000_103.13.1009.17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.14.1724"},{"key":"2025091922572772000_103.13.1009.18","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.551812"},{"key":"2025091922572772000_103.13.1009.19","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.11.1233"},{"key":"2025091922572772000_103.13.1009.20","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2013.192"},{"key":"2025091922572772000_103.13.1009.21","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-87"},{"key":"2025091922572772000_103.13.1009.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2013.09.003"},{"key":"2025091922572772000_103.13.1009.23","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.721027"},{"key":"2025091922572772000_103.13.1009.24","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7113.912"},{"key":"2025091922572772000_103.13.1009.25","first-page":"2985","article-title":"AHA\/ACC\/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and The Obesity Society","volume":"2014","author":"Jensen","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"Suppl 4","key":"2025091922572772000_103.13.1009.26","first-page":"354S","article-title":"Outcome success in obesity","volume":"9","author":"Klein","year":"2001","journal-title":"Obes Res"},{"key":"2025091922572772000_103.13.1009.27","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201306-166OC"},{"key":"2025091922572772000_103.13.1009.28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2012.01303.x"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heartjnl-2016-310757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T05:57:36Z","timestamp":1758347856000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heartjnl-2016-310757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,16]]},"references-count":28,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2017,6,14]]},"published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1136\/heartjnl-2016-310757"],"URL":"https:\/\/doi.org\/10.1136\/heartjnl-2016-310757","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,16]]}}}