{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:16:54Z","timestamp":1759882614958,"version":"build-2065373602"},"reference-count":5,"publisher":"BMJ","issue":"17","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[2017,4,27]]},"published-print":{"date-parts":[[2017,9]]},"abstract":"\n Clinical introduction<\/jats:title>\n A 53-year-old woman with no previous\u00a0medical history complained of easy fatigue over the last 6 months. She had a positive family history for coronary artery disease but no other risk factors. On physical examination, a 3\/6 pansystolic murmur was heard over the apex, and the lung auscultation was unremarkable. Her ECG showed a left anterior fascicular block, with poor R wave progression in the anterior leads (see online supplementary image A). A subsequent echocardiogram revealed a slightly dilated for the patient\u2019s body surface area (BSA) (1.73\u2009m2<\/jats:sup>) left ventricle (55\/35\u2009mm), with preserved systolic function and a moderate functional mitral regurgitation. The estimated pulmonary artery pressure was 45\u2009mm\u00a0Hg. During treadmill radionuclide scintigraphy, her exercise tolerance was normal, with good inotropic response, and 96% oxygen saturation at rest and at peak exercise. A 2\u2009mm ST segment depression was noted at peak effort, which persisted well into recovery (see online supplementary image B). The scintigraphy scan showed extensive reversible anteroapical wall ischaemia (see online supplementary image C). At this point she was referred to us for right and left heart catheterisation. Intracardiac pressures and saturations were: right atrium (RA)RA=3\u2009mm\u00a0Hg, right ventricle (RV)=26\/3\u2009mm\u00a0Hg, Pulmonary artery (PA)=26\/10\/mean 16\u2009mm Hg, pulmonary capillary wedge pressure (PCWP)=11\u2009mm\u00a0Hg, left ventricle (LV)=110\/10\u2009mm\u00a0Hg, Aorta\u00a0(Ao)=110\/60\/mean 80\u2009mm\u00a0Hg, Superior vena cava saturation (SVCsat)=62%, RAsat=62%, PAsat=78%, Aosat=96%\u2009and estimated pulmonary to systematic flow ratio\u00a0(Qp\/Qs)=1.8. Her coronary angiography and CT angiography are shown in\u00a0figure 1A,B.<\/jats:p>\n \n \n Supplementary material 1<\/jats:title>\n <\/jats:caption>\n \n \n <\/jats:p>\n <\/jats:supplementary-material>\n \n \n Supplementary material 2<\/jats:title>\n <\/jats:caption>\n \n \n <\/jats:p>\n <\/jats:supplementary-material>\n \n \n Supplementary material 3<\/jats:title>\n <\/jats:caption>\n \n \n <\/jats:p>\n <\/jats:supplementary-material>\n \n Figure 1<\/jats:label>\n \n Coronary and CT angiograms.<\/jats:p>\n <\/jats:caption>\n \n <\/jats:fig>\n <\/jats:sec>\n \n Question<\/jats:title>\n What is the most likely diagnosis?\n \n Right coronary fistula to right ventricle<\/jats:p>\n <\/jats:list-item>\n \n Kawasaki disease with fistula<\/jats:p>\n <\/jats:list-item>\n \n Anomalous origin of the left coronary artery from the pulmonary artery<\/jats:p>\n <\/jats:list-item>\n \n Persistent truncus arteriosus<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1136\/heartjnl-2017-311256","type":"journal-article","created":{"date-parts":[[2017,6,10]],"date-time":"2017-06-10T20:20:10Z","timestamp":1497126010000},"page":"1390-1391","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Dyspnoea on exertion in a 53-year-old woman"],"prefix":"10.1136","volume":"103","author":[{"given":"Eftihia","family":"Sbarouni","sequence":"first","affiliation":[{"name":"Division of Interventional Cardiology, Onassis Cardiac Surgery Center, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiota","family":"Georgiadou","sequence":"additional","affiliation":[{"name":"Division of Interventional Cardiology, Onassis Cardiac Surgery Center, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassilis","family":"Voudris","sequence":"additional","affiliation":[{"name":"Division of Interventional Cardiology, Onassis Cardiac Surgery Center, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,6,10]]},"reference":[{"key":"2025100702423868000_103.17.1390.1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq087"},{"key":"2025100702423868000_103.17.1390.2","first-page":"564","article-title":"Late presentation of an anomalous origin of the left coronary artery from the pulmonary artery: case report and review","volume":"20","author":"Ramana","year":"2008","journal-title":"J Invasive Cardiol"},{"key":"2025100702423868000_103.17.1390.3","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20848"},{"key":"2025100702423868000_103.17.1390.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000016175.49835.57"},{"key":"2025100702423868000_103.17.1390.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-007-1005-x"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heartjnl-2017-311256","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T09:42:43Z","timestamp":1759830163000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heartjnl-2017-311256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,10]]},"references-count":5,"journal-issue":{"issue":"17","published-online":{"date-parts":[[2017,8,15]]},"published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1136\/heartjnl-2017-311256"],"URL":"https:\/\/doi.org\/10.1136\/heartjnl-2017-311256","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"type":"print","value":"1355-6037"},{"type":"electronic","value":"1468-201X"}],"subject":[],"published":{"date-parts":[[2017,6,10]]}}}