{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:53:09Z","timestamp":1758477189337,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","issue":"24","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[2018,7,26]]},"published-print":{"date-parts":[[2018,12]]},"abstract":"\n Clinical introduction<\/jats:title>\n A 52-year-old woman with shortness of breath and palpitations was referred to a cardiologist. A 24-hour Holter demonstrated high density (37%) of ventricular premature beats (VPBs) and long runs of non-sustained (eventually sustained) monomorphic ventricular tachycardia (VT) with the same morphology as several VPBs detected in a 12-lead ECG (figure 1A). A\u00a0transthoracic echocardiogram was performed, and the patient\u2019s evaluation was completed with a functional and gadolinium-enhanced cardiovascular MR (CMR) study (figure 1B,C) to assess structural heart disease. In a follow-up visit, an electrophysiological study (EPS) was performed to identify the origin of VPBs and VT (figure 1D).<\/jats:p>\n \n Figure 1<\/jats:label>\n \n (A)\u00a0A 12-lead ECG. (B) Cine CMR-SSFP (steady-state-free-precession) sequence on a three-chamber view. (C) Inversion-recovery gradient\u00a0echo CMR pulse sequence for delayed enhancement assessment. (D) Three-dimensional electroanatomic voltage mapping of the left ventricular cavity (cranial\u00a0left anterior oblique view).\u00a0CMR, cardiovascular MR.<\/jats:p>\n <\/jats:caption>\n \n <\/jats:fig>\n <\/jats:sec>\n \n Question<\/jats:title>\n What is the most likely cause of VPBs and VT?\n \n Idiopathic VT in the absence of structural heart disease.<\/jats:p>\n <\/jats:list-item>\n \n Bileaflet mitral valve prolapse\u00a0(MVP).<\/jats:p>\n <\/jats:list-item>\n \n Dilated cardiomyopathy.<\/jats:p>\n <\/jats:list-item>\n \n Left ventricular non-compaction cardiomyopathy.<\/jats:p>\n <\/jats:list-item>\n \n Ischaemic cardiomyopathy.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1136\/heartjnl-2018-313347","type":"journal-article","created":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T12:15:38Z","timestamp":1536063338000},"page":"2025-2043","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["A 52-year-old woman with ventricular tachycardia"],"prefix":"10.1136","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1530-5742","authenticated-orcid":false,"given":"Ana","family":"Fidalgo","sequence":"first","affiliation":[{"name":"HM Hospitales-Centro Integral de Enfermedades Cardiovasculares HM-CIEC, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia","family":"Fernandez-Friera","sequence":"additional","affiliation":[{"name":"HM Hospitales-Centro Integral de Enfermedades Cardiovasculares HM-CIEC, Madrid, Spain"},{"name":"Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Solis","sequence":"additional","affiliation":[{"name":"HM Hospitales-Centro Integral de Enfermedades Cardiovasculares HM-CIEC, Madrid, Spain"},{"name":"Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"2025092012420206000_104.24.2025.1","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"2017","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"2025092012420206000_104.24.2025.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01152-4"},{"key":"2025092012420206000_104.24.2025.3","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-302048"},{"key":"2025092012420206000_104.24.2025.4","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.016291"},{"key":"2025092012420206000_104.24.2025.5","first-page":"4","article-title":"Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse","volume":"2018","author":"Fern\u00e1ndez-Friera","year":"2018","journal-title":"Glob Cardiol Sci Pract"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/heartjnl-2018-313347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:42:09Z","timestamp":1758397329000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/heartjnl-2018-313347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,4]]},"references-count":5,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2018,11,27]]},"published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1136\/heartjnl-2018-313347"],"URL":"https:\/\/doi.org\/10.1136\/heartjnl-2018-313347","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"type":"print","value":"1355-6037"},{"type":"electronic","value":"1468-201X"}],"subject":[],"published":{"date-parts":[[2018,9,4]]}}}