{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:43:59Z","timestamp":1787499839130,"version":"build-2736575974"},"reference-count":11,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2004,2]]},"abstract":"\n Objective:<\/jats:bold>\n To quantify non-invasively right ventricular (RV) performance in infants after stage 1 palliation for hypoplastic left heart syndrome (HLHS).\n <\/jats:p>\n \n Design:<\/jats:bold>\n Prospective, observational study with two dimensional and strain Doppler echocardiography.\n <\/jats:p>\n \n Setting:<\/jats:bold>\n Single tertiary paediatric cardiology centre.\n <\/jats:p>\n \n Patients:<\/jats:bold>\n Convenience sample of nine consecutive infants with HLHS. Four whose surgery involved a systemic to pulmonary artery (S-PA) shunt were compared with five whose surgery incorporated a right ventricle to pulmonary artery (RV-PA) conduit.\n <\/jats:p>\n \n Methods:<\/jats:bold>\n Basal RV free wall longitudinal strain rate, systolic strain (\u03f5), and RV percentage area change were calculated during a single assessment between 27\u201350 days after surgery.\n <\/jats:p>\n \n Results:<\/jats:bold>\n Cardiopulmonary bypass time was longer in patients who underwent RV-PA (226 (30) minutes\n v<\/jats:italic>\n 181 (18) minutes, p \u200a=\u200a 0.03), but cross clamp time, duration of ventilation, and inotrope use did not differ. Two patients in the S-PA group died, on days 29 and 60 after surgery. Peak systolic strain rate (\u22121.24 (0.19)\/s\n v<\/jats:italic>\n \u22120.91 (0.21)\/s, p \u200a=\u200a 0.048), peak \u03f5 (\u221217.8 (1.8)%\n v<\/jats:italic>\n \u201313.4 (2.0)%, p \u200a=\u200a 0.01), and RV percentage area change (56 (6)%\n v<\/jats:italic>\n 25 (6)%, p < 0.01) were all greater among RV-PA patients. These indices also tended to be greater in survivors as a group. Ventricular loading conditions (oxygen saturations, diuretic treatment, and blood pressure) were similar in both groups.\n <\/jats:p>\n \n Conclusion:<\/jats:bold>\n Strain Doppler echocardiography shows improved RV longitudinal systolic contractility in patients during convalescence after the RV-PA modification of stage 1 palliation for HLHS compared with those with an S-PA shunt.\n <\/jats:p>","DOI":"10.1136\/hrt.2003.016675","type":"journal-article","created":{"date-parts":[[2004,1,16]],"date-time":"2004-01-16T19:43:19Z","timestamp":1074282199000},"page":"191-194","source":"Crossref","is-referenced-by-count":54,"title":["Improved early ventricular performance with a right ventricle to pulmonary artery conduit in stage 1 palliation for hypoplastic left heart syndrome: evidence from strain Doppler echocardiography"],"prefix":"10.1136","volume":"90","author":[{"given":"M L","family":"Hughes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L S","family":"Shekerdemian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C P","family":"Brizard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D J","family":"Penny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2004,1,16]]},"reference":[{"key":"2025101714470197000_90.2.191.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(80)90224-6"},{"key":"2025101714470197000_90.2.191.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(98)70448-9"},{"key":"2025101714470197000_90.2.191.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70118-2"},{"key":"2025101714470197000_90.2.191.4","first-page":"1961","volume":"106","year":"2002","journal-title":"Circulation"},{"key":"2025101714470197000_90.2.191.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.10.1158"},{"key":"2025101714470197000_90.2.191.6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000019907.77526.75"},{"key":"2025101714470197000_90.2.191.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01131-0"},{"key":"2025101714470197000_90.2.191.8","doi-asserted-by":"publisher","DOI":"10.1053\/euje.2000.0031"},{"key":"2025101714470197000_90.2.191.9","first-page":"307","volume":"i","year":"1986","journal-title":"Lancet"},{"key":"2025101714470197000_90.2.191.10","doi-asserted-by":"publisher","DOI":"10.2307\/2532051"},{"key":"2025101714470197000_90.2.191.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(96)90058-9"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2003.016675","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T21:47:09Z","timestamp":1760737629000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2003.016675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,16]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2004,1,16]]},"published-print":{"date-parts":[[2004,2]]}},"alternative-id":["10.1136\/hrt.2003.016675"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2003.016675","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1,16]]}}}