{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:14:42Z","timestamp":1782602082930,"version":"3.54.5"},"reference-count":24,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To identify fetal echocardiographic features, associations, and outcome of atrioventricular and ventriculoarterial discordance.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Design:<\/jats:bold> Retrospective analysis of videotape recordings of fetal echocardiograms and examination of departmental database and patient records to establish outcome.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Setting:<\/jats:bold> Tertiary centre for fetal cardiology.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Patients:<\/jats:bold> 34 consecutive fetuses with a prenatal diagnosis of double discordance seen between January 1993 and December 2003.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Main outcome measures:<\/jats:bold> Echocardiographic features including reversed differential insertion, identification of the right ventricle through the moderator band, and the origin and orientation of the great arteries. All associated cardiac abnormalities and outcome.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> Reversed differential insertion was identified in 26 fetuses. The right ventricle could be identified by the moderator band in 30 fetuses and was left sided in all but one. A parallel or abnormal orientation of the great arteries was seen in all fetuses. Only five of 34 cases were isolated from a cardiac viewpoint. There was a ventricular septal defect in 21, Ebstein\u2019s anomaly in 8, pulmonary stenosis in 12, coarctation of the aorta in 6, tricuspid atresia in 2, congenital heart block in 2 fetuses prenatally, and dextrocardia in 6. Nineteen babies survived; one baby died in the neonatal period and three in infancy. Eleven pregnancies were interrupted.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> A left sided or posterior right ventricle, identified by reversed differential insertion or the moderator band, in association with abnormal orientation of the great arteries should alert a sonographer to the diagnosis of double discordance. Isolated cases are rare prenatally (14%) but the short term survival in our fetal series is good. Where pregnancy was continued, 19 of 23 babies (82%) remained alive.<\/jats:p>","DOI":"10.1136\/hrt.2004.052548","type":"journal-article","created":{"date-parts":[[2005,3,10]],"date-time":"2005-03-10T21:54:24Z","timestamp":1110491664000},"page":"1453-1458","source":"Crossref","is-referenced-by-count":60,"title":["Atrioventricular and ventriculoarterial discordance (congenitally corrected transposition of the great arteries): echocardiographic features, associations, and outcome in 34 fetuses"],"prefix":"10.1136","volume":"91","author":[{"given":"G","family":"Sharland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Tingay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2005,3,10]]},"reference":[{"key":"2025092014093945000_91.11.1453.1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1651-2227.1976.tb16529.x","volume":"65","year":"1976","journal-title":"Acta Paediatr Scand"},{"key":"2025092014093945000_91.11.1453.2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1542\/peds.65.2.377","volume":"65","year":"1980","journal-title":"Pediatrics"},{"key":"2025092014093945000_91.11.1453.3","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.52.3.248"},{"key":"2025092014093945000_91.11.1453.4","unstructured":"Von Rokitansky K. 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