{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:01:36Z","timestamp":1790431296419,"version":"4.1.0"},"reference-count":5,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:sec>\n                  <jats:title>Background:<\/jats:title>\n                  <jats:p>Interventional procedures in adults with congenital cardiac conditions often require insertion of large-sized sheaths into the femoral veins. Data on the use of suture-mediated devices for femoral venous access site closure are scant and no data are available regarding venous patency after device use.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>To assess the efficacy of the 6Fr Perclose (Abbott Vascular Devices, CA, USA) suture-mediated device in achieving haemostasis and venous patency after closure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design and setting:<\/jats:title>\n                  <jats:p>146 consecutive patients (80 women, mean (SD) age 45 (14) years) undergoing closure of 205 femoral venous access sites in a tertiary cardiac centre were studied. All received heparin and were taking concomitant aspirin or clopidogrel, or both. The majority (98%) had a \u2a7e10Fr sheath inserted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Immediate haemostasis was achieved in 202 (99%) sites. Two patients (1.4%) had a major complication. On follow-up (111 patients, mean (SD) 71 (33) days) there was no evidence of haematoma or fistula formation. Doppler studies from a subgroup of 43 (29%) patients (mean (SD) age 45 (15) years, mean (SD) follow-up 47 (18) days) showed a common femoral venous diameter of 11.6 (2.7) mm on the device closed right and 12.2 (2.5) mm on the left vein (p&gt;0.05). All accessed veins were patent with no pseudoaneurysm or arteriovenous fistula formation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Pre-closure of large-size sheath femoral venous access sites using the suture-mediated Perclose device is efficacious in achieving rapid haemostasis in the presence of anticoagulation. Doppler follow-up shows no loss of venous patency or luminal venous diameter as compared with the contralateral side.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/hrt.2006.095935","type":"journal-article","created":{"date-parts":[[2006,11,3]],"date-time":"2006-11-03T20:34:35Z","timestamp":1162586075000},"page":"571-572","source":"Crossref","is-referenced-by-count":39,"title":["Pre-closure of femoral venous access sites used for large-sized sheath insertion with the Perclose device in adults undergoing cardiac intervention: Figure 1"],"prefix":"10.1136","volume":"94","author":[{"given":"V S","family":"Mahadevan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Jimeno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L N","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P R","family":"McLaughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E M","family":"Horlick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2006,11,3]]},"reference":[{"key":"2025100707485222000_94.5.571.1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10294"},{"key":"2025100707485222000_94.5.571.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01725-8"},{"key":"2025100707485222000_94.5.571.3","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10086"},{"key":"2025100707485222000_94.5.571.4","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20190"},{"key":"2025100707485222000_94.5.571.5","first-page":"107","article-title":"Internal diameters of human femoral blood vessels in 50 healthy subjects using color Doppler ultrasonography.","volume":"101","author":"Macchi","year":"1996","journal-title":"Ital J Anat Embryol"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2006.095935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T14:48:58Z","timestamp":1759848538000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2006.095935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,3]]},"references-count":5,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,4,14]]},"published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1136\/hrt.2006.095935"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2006.095935","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,3]]}}}