{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T17:11:51Z","timestamp":1772817111542,"version":"3.50.1"},"reference-count":32,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p>\n                  <jats:bold>Objectives:<\/jats:bold> To evaluate the risk of cardiovascular disease in individuals with coeliac disease (CD).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Design:<\/jats:bold> Swedish national hospital-based register data were used to identify 13 358 individuals who had been diagnosed with CD (1964\u20132003) and 64 118 age-matched and sex-matched individuals without CD. Cox regression was used to estimate the risk of vascular disease in subjects with CD. Analyses were restricted to individuals with a follow-up of &gt;1 year and with no vascular disease before study entry.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> CD was associated with myocardial infarction (HR 1.27; 95% CI 1.09 to 1.48), angina pectoris (1.46; 1.25 to 1.70), heart failure (1.41; 1.22 to 1.62), brain haemorrhage (1.40; 1.05 to 1.88) and ischaemic stroke (1.35; 1.14 to 1.60). These risk estimates were similar when analyses were restricted to adults in whom vascular disease had been listed as the main diagnosis. In post-hoc analyses, where reference individuals were restricted to inpatients, no association was found between CD and later vascular disease, except for a lower risk of heart failure (0.79; 0.68 to 0.92).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> The positive association between CD and later vascular disease may be explained by ascertainment bias.<\/jats:p>","DOI":"10.1136\/hrt.2006.097097","type":"journal-article","created":{"date-parts":[[2007,2,4]],"date-time":"2007-02-04T07:39:41Z","timestamp":1170574781000},"page":"1111-1115","source":"Crossref","is-referenced-by-count":30,"title":["Vascular disease in a population-based cohort of individuals hospitalised with coeliac disease"],"prefix":"10.1136","volume":"93","author":[{"given":"J F","family":"Ludvigsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"de Faire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ekbom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S M","family":"Montgomery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2007,2,3]]},"reference":[{"key":"2025092003273956000_93.9.1111.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021687"},{"key":"2025092003273956000_93.9.1111.2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.3.286"},{"key":"2025092003273956000_93.9.1111.3","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2003.54"},{"key":"2025092003273956000_93.9.1111.4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01283.x"},{"key":"2025092003273956000_93.9.1111.5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7374.1202"},{"key":"2025092003273956000_93.9.1111.6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.570846"},{"key":"2025092003273956000_93.9.1111.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060900"},{"key":"2025092003273956000_93.9.1111.8","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.13.1566"},{"key":"2025092003273956000_93.9.1111.9","first-page":"113","volume":"2","year":"1976","journal-title":"Lancet"},{"key":"2025092003273956000_93.9.1111.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02008.x"},{"key":"2025092003273956000_93.9.1111.11","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.7.960"},{"key":"2025092003273956000_93.9.1111.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000099844.31524.05"},{"key":"2025092003273956000_93.9.1111.13","first-page":"1","volume":"2","year":"1980","journal-title":"Vital Health Stat 2"},{"key":"2025092003273956000_93.9.1111.14","unstructured":"Johannesson I. The Total Population Register of Statistics Sweden. New possibilities and better quality. \u00d6rebro: Statistics Sweden, 2005."},{"key":"2025092003273956000_93.9.1111.15","unstructured":"Guteland G. Socioekonomisk indelning (SEI). (Socioeconomic classification). [in Swedish] Reports on Statistical Co-ordination. Stockholm: Statistics Sweden (SCB - Statistiska centralbyr\u00e5n), 1982:4."},{"key":"2025092003273956000_93.9.1111.16","first-page":"1561","volume":"354","year":"1999","journal-title":"Lancet"},{"key":"2025092003273956000_93.9.1111.17","doi-asserted-by":"publisher","DOI":"10.1136\/jech.57.1.36"},{"key":"2025092003273956000_93.9.1111.18","doi-asserted-by":"publisher","DOI":"10.1126\/science.1112062"},{"key":"2025092003273956000_93.9.1111.19","unstructured":"American Heart Association and American Stroke Association. Heart disease and Stroke Statistics. 2005 Update. Dallas, TX: American Heart Association, 2005, http:\/\/www.americanheart.org\/presenter.jhtml?identifier=3000090 (accessed 27 Feb 2007)."},{"key":"2025092003273956000_93.9.1111.20","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03290450033020"},{"key":"2025092003273956000_93.9.1111.21","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7304.75"},{"key":"2025092003273956000_93.9.1111.22","doi-asserted-by":"publisher","DOI":"10.1136\/gut.39.1.60"},{"key":"2025092003273956000_93.9.1111.23","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1093\/ajcn\/72.4.937","volume":"72","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"2025092003273956000_93.9.1111.24","doi-asserted-by":"publisher","DOI":"10.1080\/14034940310006203"},{"key":"2025092003273956000_93.9.1111.25","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.1999.00403.x"},{"key":"2025092003273956000_93.9.1111.26","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.18.2363"},{"key":"2025092003273956000_93.9.1111.27","first-page":"2342","volume":"95","year":"1998","journal-title":"Lakartidningen"},{"key":"2025092003273956000_93.9.1111.28","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.032094"},{"key":"2025092003273956000_93.9.1111.29","first-page":"598","volume":"91","year":"1994","journal-title":"Lakartidningen"},{"key":"2025092003273956000_93.9.1111.30","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000014607.90464.88"},{"key":"2025092003273956000_93.9.1111.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2004.01.007"},{"key":"2025092003273956000_93.9.1111.32","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.537878"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2006.097097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T10:27:49Z","timestamp":1758364069000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2006.097097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,3]]},"references-count":32,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2007,8,14]]},"published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1136\/hrt.2006.097097"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2006.097097","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,3]]}}}