{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:32:17Z","timestamp":1790793137462,"version":"4.1.0"},"reference-count":33,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To describe the characteristics of sudden arrhythmic death syndrome (SADS) and compare its incidence with official national mortality statistics for unascertained deaths.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Design and setting:<\/jats:bold> Sudden unexplained deaths were prospectively surveyed through 117 coroners\u2019 jurisdictions in England. Consecutive cases meeting the following criteria were included: white Caucasian, aged 4\u201364 years, no history of cardiac disease, last seen alive within 12 h of death, normal coroner\u2019s autopsy, cardiac pathologist\u2019s confirmation of a normal heart and negative toxicology.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Main outcome measures:<\/jats:bold> The estimated mortality from SADS was calculated and the official mortality statistics for unascertained causes of deaths in 4\u201364-year-olds was identified for the same time period.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> 115 coroner\u2019s cases were reported and 56 (49%) SADS victims were identified: mean age 32 years, range 7\u201364 years and 35 (63%) male. 7 of 39 cases (18%) had a family history of other premature sudden deaths (&lt;45). The estimated mortality from SADS was 0.16\/100 000 per annum (95% CI 0.12 to 0.21), compared with an official mortality of 0.10\/100 000 per annum for International Classification of Diseases 798.1 (sudden death, cause unknown\u2014instantaneous death) or 1.34\/100 000 per annum for unascertained causes of death.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> Deaths from SADS occur predominantly in young males. When compared with official mortality, the incidence of SADS may be up to eight times higher than estimated: more than 500 potential SADS cases per annum in England. Families with SADS carry genetic cardiac disease, placing them at risk of further sudden deaths. SADS should therefore be a certifiable cause of death prompting specialised cardiological evaluation of families.<\/jats:p>","DOI":"10.1136\/hrt.2006.099598","type":"journal-article","created":{"date-parts":[[2007,1,19]],"date-time":"2007-01-19T20:14:15Z","timestamp":1169237655000},"page":"601-605","source":"Crossref","is-referenced-by-count":122,"title":["Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death"],"prefix":"10.1136","volume":"93","author":[{"given":"E R","family":"Behr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Casey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Sheppard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T 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