{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T07:02:00Z","timestamp":1765609320167,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To identify risk factors for clinical-driven target lesion revascularisation (TLR) in patients treated with sirolimus-eluting (Cypher) or paclitaxel-eluting (Taxus) stents in a real-world scenario.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Design:<\/jats:bold> From 1 January 2003 to 18 May 2005, all patients treated with a Cypher or Taxus stent were consecutively registered and followed for 9 months. Re-intervention was driven by clinical symptoms.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Setting:<\/jats:bold> Western Denmark Heart Registry.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Patients:<\/jats:bold> 4432 patients with 6102 lesions treated with a Cypher (n\u200a=\u200a3791 lesions) or Taxus (n\u200a=\u200a2311 lesions) stent.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Interventions:<\/jats:bold> Percutaneous coronary intervention.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Main outcome measures:<\/jats:bold> TLR, defined as either new percutaneous coronary intervention or coronary artery bypass graft operation of the target lesion, within 9 months from the index procedure.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> TLR within 9 months was performed in 2.5% of lesions treated with the Cypher stent and in 3.3% of lesions treated with the Taxus stent (OR 1.36, 95% CI 1.00 to 1.84). After adjustment by multivariate logistic regression, Taxus stent implantation was an independent predictor of TLR (OR 1.43, 95% CI 1.05 to 1.95). Implantation of &gt;1 stent per lesion (OR 1.62, 95% CI 1.13 to 2.33) and reference diameter &lt;2.8 mm (OR 1.42, 95% CI 1.00 to 2.02) were also identified as independent predictors of TLR.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> These data from the registry reflect a real-world clinical scenario with operator-driven use of drug-eluting stents and symptom-driven re-intervention. In this setting, use of the Taxus stent, implantation of multiple stents per lesion and stent implantation in small vessels were independent predictors of TLR.<\/jats:p>","DOI":"10.1136\/hrt.2006.100594","type":"journal-article","created":{"date-parts":[[2006,12,28]],"date-time":"2006-12-28T20:13:19Z","timestamp":1167336799000},"page":"694-697","source":"Crossref","is-referenced-by-count":11,"title":["Target lesion revascularisation in patients treated with a sirolimus-eluting or paclitaxel-eluting stent"],"prefix":"10.1136","volume":"93","author":[{"given":"Michael","family":"Maeng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisette","family":"Okkels Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Flensted Lassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Romer Krusell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Thayssen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leif","family":"Thuesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2006,12,28]]},"reference":[{"key":"2025092001183433000_93.6.694.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"2025092001183433000_93.6.694.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"2025092001183433000_93.6.694.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012843"},{"key":"2025092001183433000_93.6.694.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"2025092001183433000_93.6.694.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.008"},{"key":"2025092001183433000_93.6.694.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.062"},{"key":"2025092001183433000_93.6.694.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.2.165"},{"key":"2025092001183433000_93.6.694.8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044372"},{"key":"2025092001183433000_93.6.694.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051175"},{"key":"2025092001183433000_93.6.694.10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.8.895"},{"key":"2025092001183433000_93.6.694.11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.7.819"},{"key":"2025092001183433000_93.6.694.12","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.075960"},{"key":"2025092001183433000_93.6.694.13","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.061622"},{"key":"2025092001183433000_93.6.694.14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200006223422507"},{"key":"2025092001183433000_93.6.694.15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200006223422506"},{"key":"2025092001183433000_93.6.694.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.045"},{"key":"2025092001183433000_93.6.694.17","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.601823"},{"key":"2025092001183433000_93.6.694.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00380-0"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2006.100594","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T08:18:43Z","timestamp":1758356323000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2006.100594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12,28]]},"references-count":18,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2007,5,14]]},"published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1136\/hrt.2006.100594"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2006.100594","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"type":"print","value":"1355-6037"},{"type":"electronic","value":"1468-201X"}],"subject":[],"published":{"date-parts":[[2006,12,28]]}}}