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There is strong evidence that with LVAD unloading, particularly when combined with pharmacological treatment, the patients\u2019 myocardial function can also recover, allowing device removal and avoiding the need for transplantation, immunosuppression and its associated complications. This indication, known as \u201cbridge to recovery\u201d is a newer and expanding indication. The future use of LVADs, particularly as survival continues to increase, is extending to their wider use as destination therapy, when the device is inserted lifelong as an alternative to transplantation, and this role is likely to increase further. LVAD technology is evolving quickly, survival is improving, the incidence of complications is decreasing and durability of the devices is improving.<\/jats:p>","DOI":"10.1136\/hrt.2007.130740","type":"journal-article","created":{"date-parts":[[2009,7,17]],"date-time":"2009-07-17T20:18:52Z","timestamp":1247861932000},"page":"63-71","source":"Crossref","is-referenced-by-count":50,"title":["Left ventricular assist devices"],"prefix":"10.1136","volume":"96","author":[{"given":"E J","family":"Birks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2009,7,16]]},"reference":[{"key":"2025100707334185000_96.1.63.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(71)90076-2"},{"key":"2025100707334185000_96.1.63.2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(69)90460-3"},{"key":"2025100707334185000_96.1.63.3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1594.2000.06635.x"},{"key":"2025100707334185000_96.1.63.4","unstructured":"Kirklin JK Frazier OH . 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