{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:41:43Z","timestamp":1791250903518,"version":"4.1.0"},"reference-count":30,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2009,1,15]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Repair of neonatal tetralogy of Fallot (TOF) has low mortality. Debate continues regarding the initial management of cyanotic or duct-dependent infants with TOF and adverse risk factors. While repair can and has been performed in these patients, it is associated with increased morbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We review the effectiveness of right ventricular outflow tract (RVOT) stenting in the symptomatic young infant with TOF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Clinical, echocardiographic, angiographic and haemodynamic data were reviewed for nine patients who underwent 11 RVOT stenting procedures from October 1994 to August 2007.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The pulmonary valve was deemed unsalvageable in all patients (median valve diameter 3.7 mm (range 2.7\u20134.2), Z-score \u22126.7 (range \u22129.7 to \u22125.4). RVOT stenting improved arterial oxygen saturation from a median of 73% (60\u201385%) to 94% (90\u201398%) (p\u200a=\u200a0.008). Median Z-score for the left pulmonary artery increased from \u22124.9 (\u22127.8 to \u22122.4) before stent implantation to \u22121.5 (\u22124.2 to \u22120.2) (p\u200a=\u200a0.02) before surgical repair. Median Z-score for the right pulmonary artery increased from \u22123.7 (\u22126.8 to \u22121.9) to \u22120.8 (\u22122.5 to 0.1) (p\u200a=\u200a0.008). Median Nakata index increased from 56 mm\n                      <jats:sup>2<\/jats:sup>\n                      \/m\n                      <jats:sup>2<\/jats:sup>\n                      (21\u201377) to 150 mm\n                      <jats:sup>2<\/jats:sup>\n                      \/m\n                      <jats:sup>2<\/jats:sup>\n                      (123\u2013231) (p\u200a=\u200a0.008). There were no procedural complications. Six patients have undergone successful repair. There were no deaths.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In the symptomatic young infant with TOF, stenting of the RVOT provides a safe and effective management strategy, improving arterial oxygen saturation and encouraging pulmonary artery growth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/hrt.2007.135723","type":"journal-article","created":{"date-parts":[[2008,3,10]],"date-time":"2008-03-10T20:25:17Z","timestamp":1205180717000},"page":"142-147","source":"Crossref","is-referenced-by-count":121,"title":["Stenting of the right ventricular outflow tract in the symptomatic infant with tetralogy of Fallot"],"prefix":"10.1136","volume":"95","author":[{"given":"G","family":"Dohlen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R R","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L N","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Ozawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G S","family":"Van Arsdell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D S","family":"Fruitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K-J","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2008,3,10]]},"reference":[{"issue":"(suppl III)","key":"2025091923103547000_95.2.142.1","first-page":"III123","article-title":"What is the optimal age for repair of tetralogy of Fallot?","volume":"102","author":"Van Arsdell","year":"2000","journal-title":"Circulation"},{"key":"2025091923103547000_95.2.142.2","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S0022-5223(12)70161-7","article-title":"Surgery for tetralogy of Fallot at less than six months of age.","volume":"107","author":"Uva","year":"1994","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025091923103547000_95.2.142.3","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0022-5223(19)35272-9","article-title":"Prediction of severe obstruction to right ventricular outflow after repair of tetralogy of Fallot and pulmonary atresia.","volume":"96","author":"Blackstone","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025091923103547000_95.2.142.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.02.010"},{"key":"2025091923103547000_95.2.142.5","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00044-7"},{"key":"2025091923103547000_95.2.142.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)01182-6"},{"key":"2025091923103547000_95.2.142.7","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1161\/01.CIR.91.5.1506","article-title":"Early balloon dilation of the pulmonary valve in infants with tetralogy of Fallot.","volume":"91","author":"Sluysmans","year":"1995","journal-title":"Circulation"},{"key":"2025091923103547000_95.2.142.8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0735-1097(10)80235-9","article-title":"Results of balloon pulmonary valvuloplasty as a palliative procedure in tetralogy of Fallot.","volume":"18","author":"Sreeram","year":"1990","journal-title":"J Am Coll Cardiol"},{"key":"2025091923103547000_95.2.142.9","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.60.3.232"},{"key":"2025091923103547000_95.2.142.10","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1997.0751"},{"key":"2025091923103547000_95.2.142.11","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0022-5223(19)36802-3","article-title":"Neonatal repair of tetralogy of Fallot with and without pulmonary atresia.","volume":"101","author":"Di Donato","year":"1991","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025091923103547000_95.2.142.12","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21119"},{"key":"2025091923103547000_95.2.142.13","unstructured":"R Development Core Team. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing, 2007. http:\/\/www.R-project.org ."},{"key":"2025091923103547000_95.2.142.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70113-2"},{"key":"2025091923103547000_95.2.142.15","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951101000701"},{"key":"2025091923103547000_95.2.142.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00921-2"},{"key":"2025091923103547000_95.2.142.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)03619-6"},{"key":"2025091923103547000_95.2.142.18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.652172"},{"key":"2025091923103547000_95.2.142.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70076-5"},{"key":"2025091923103547000_95.2.142.20","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.25.e157"},{"key":"2025091923103547000_95.2.142.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.09.010"},{"key":"2025091923103547000_95.2.142.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.09.053"},{"key":"2025091923103547000_95.2.142.23","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000024254.18659.22"},{"key":"2025091923103547000_95.2.142.24","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.4.612"},{"key":"2025091923103547000_95.2.142.25","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.77.2.176"},{"key":"2025091923103547000_95.2.142.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.10.068"},{"key":"2025091923103547000_95.2.142.27","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1046\/j.1540-8183.2003.08032.x","article-title":"Unusual stents in infants with severe congenital heart disease.","volume":"16","author":"Vincent","year":"2003","journal-title":"J Interven Cardiol"},{"key":"2025091923103547000_95.2.142.28","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.4.1691"},{"key":"2025091923103547000_95.2.142.29","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70305-5"},{"key":"2025091923103547000_95.2.142.30","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00700-1"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2007.135723","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T06:10:45Z","timestamp":1758348645000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2007.135723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,10]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2008,12,24]]},"published-print":{"date-parts":[[2009,1,15]]}},"alternative-id":["10.1136\/hrt.2007.135723"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2007.135723","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,10]]}}}