{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T02:41:40Z","timestamp":1794192100841,"version":"4.8.0"},"reference-count":25,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To develop, in patients referred for syncope to an emergency department (ED), a diagnostic score to identify those patients likely to have a cardiac cause.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>ED of 14 general hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>516 consecutive patients with unexplained syncope.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>Subjects underwent a diagnostic evaluation on adherence to Guidelines of the European Society of Cardiology. The clinical features of syncope were analysed using a standard 52-item form. In a validation cohort of 260 patients the predictive value of symptoms\/signs was evaluated, a point score was developed and then validated in a cohort of 256 other patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measurements:<\/jats:title>\n                    <jats:p>Diagnosis of cardiac syncope, mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Abnormal ECG and\/or heart disease, palpitations before syncope, syncope during effort or in supine position, absence of autonomic prodromes and absence of predisposing and\/or precipitating factors were found to be predictors of cardiac syncope. To each variable a score from +4 to \u20131 was assigned to the magnitude of regression coefficient. A score \u2a7e3 identified cardiac syncope with a sensitivity of 95%\/92% and a specificity of 61%\/69% in the derivation and validation cohorts, respectively. During follow-up (mean (SD) 614 (73) days) patients with score \u2a7e3 had a higher total mortality than patients with a score &lt;3 both in the derivation (17% vs 3%; p&lt;0.001) and in the validation cohort (21% vs 2%; p&lt;0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A simple score derived from clinical history can be usefully employed for the triage and management of patients with syncope in an ED.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/hrt.2008.143123","type":"journal-article","created":{"date-parts":[[2008,6,2]],"date-time":"2008-06-02T20:56:08Z","timestamp":1212440168000},"page":"1620-1626","source":"Crossref","is-referenced-by-count":274,"title":["Clinical predictors of cardiac syncope at initial evaluation in patients referred urgently to a general hospital: the EGSYS score"],"prefix":"10.1136","volume":"94","author":[{"given":"A","family":"Del Rosso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Ungar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Maggi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Giada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N R","family":"Petix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"De Santo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Menozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Brignole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2008,6,2]]},"reference":[{"key":"2025092001142729000_94.12.1620.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90913-5"},{"key":"2025092001142729000_94.12.1620.2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330100023024"},{"key":"2025092001142729000_94.12.1620.3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi647"},{"key":"2025092001142729000_94.12.1620.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.eupc.2004.08.008"},{"key":"2025092001142729000_94.12.1620.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012407"},{"key":"2025092001142729000_94.12.1620.6","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/00005792-199005000-00004","article-title":"Evaluation and outcome of patients with syncope.","volume":"69","author":"Kapoor","year":"1990","journal-title":"Medicine (Baltimore)"},{"key":"2025092001142729000_94.12.1620.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03320440035029"},{"key":"2025092001142729000_94.12.1620.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01241-4"},{"key":"2025092001142729000_94.12.1620.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00797-5"},{"key":"2025092001142729000_94.12.1620.10","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2975"},{"key":"2025092001142729000_94.12.1620.11","doi-asserted-by":"publisher","DOI":"10.1136\/emj.19.1.23"},{"key":"2025092001142729000_94.12.1620.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.047"},{"key":"2025092001142729000_94.12.1620.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)80315-5"},{"key":"2025092001142729000_94.12.1620.14","first-page":"555","article-title":"Selection and interpretation of diagnostic tests and procedures.","volume":"94","author":"Griner","year":"1981","journal-title":"Ann Intern Med"},{"key":"2025092001142729000_94.12.1620.15","doi-asserted-by":"publisher","DOI":"10.1197\/S1069-6563(03)00535-9"},{"key":"2025092001142729000_94.12.1620.16","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi584"},{"key":"2025092001142729000_94.12.1620.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2004.11.009"},{"key":"2025092001142729000_94.12.1620.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2006.11.012"},{"key":"2025092001142729000_94.12.1620.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(02)00827-8"},{"key":"2025092001142729000_94.12.1620.20","first-page":"277","article-title":"Encuesta nacional: s\u00edncope. 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Int J Cardiol (in press)."},{"key":"2025092001142729000_94.12.1620.25","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2007.048413"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.2008.143123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T08:14:34Z","timestamp":1758356074000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.2008.143123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,2]]},"references-count":25,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2008,11,14]]},"published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1136\/hrt.2008.143123"],"URL":"https:\/\/doi.org\/10.1136\/hrt.2008.143123","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1162052.622508","asserted-by":"object"}]},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,2]]}}}