{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:21:34Z","timestamp":1783441294218,"version":"3.54.6"},"reference-count":29,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"accepted":{"date-parts":[[2010,8,16]]},"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To assess the value of left ventricular (LV) dyssynchrony, using phase analysis of nuclear single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) as independent predictor of cardiac events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Phase analysis using Emory Cardiac Toolbox was applied on gated rest MPI scans to assess LV dyssynchrony in a total of 202 patients. Follow-up was obtained in 197 patients (97.5%). Major adverse cardiac events (MACE) (cardiac death and hospitalisation for any cardiac reasons, including worsening of heart failure, non-fatal myocardial infarction, unstable angina and coronary revascularisation) were determined using the Kaplan\u2013Meier method. Cox proportional hazard regression was used to identify independent predictors of cardiac events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>At a median follow-up of 3.2\u00b11.2\u2005years, 41 patients had at least one event, including 5 cardiac deaths. LV dyssynchrony (n=35) was associated with a significantly higher incidence of MACE (p&lt;0.001) and proved to be an independent predictor of cardiac events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>LV dyssynchrony assessed by phase analysis of gated SPECT-MPI is a strong predictor of MACE independent of other known predictors such as perfusion defects or decreased LV ejection fraction.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/hrt.2010.201566","type":"journal-article","created":{"date-parts":[[2010,10,21]],"date-time":"2010-10-21T20:18:57Z","timestamp":1287692337000},"page":"33-37","source":"Crossref","is-referenced-by-count":72,"title":["Long-term prognostic value of left ventricular dyssynchrony assessment by phase analysis from myocardial perfusion imaging"],"prefix":"10.1136","volume":"97","author":[{"given":"Aju 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