{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:22:22Z","timestamp":1758399742627},"reference-count":18,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[1971,11,1]]},"DOI":"10.1136\/hrt.33.6.889","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:46:00Z","timestamp":1190151960000},"page":"889-894","source":"Crossref","is-referenced-by-count":37,"title":["Clinical, electrocardiographic, and haemodynamic effects of long-term use of propranolol in Prinzmetal's variant angina pectoris."],"prefix":"10.1136","volume":"33","author":[{"given":"M","family":"Guazzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Magrini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Fiorentini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Polese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"03","article-title":"1969. Evaluation of long-term use of propranolol in angina pectoris","volume":"210","author":"Amsterdam, E.A.; Gorlin, R.; Wolfson, S.","unstructured":"Amsterdam, E. A., Gorlin, R., and Wolfson, S. 1969. Evaluation of long-term use of propranolol in angina pectoris. Journal of the American Medical Association, 210, I03.","journal-title":"Journal of the American Medical Association"},{"key":"ref_2","first-page":"399","article-title":"Appraisal of drugs intended to alter subjective responses, symptoms","volume":"158","author":"Beecher, H.K.","year":"1955","unstructured":"Beecher, H. K. 1955. Appraisal of drugs intended to alter subjective responses, symptoms. Journal of the American Medical Association, 158, 399.","journal-title":"Journal of the American Medical Association"},{"key":"ref_3","first-page":"3","article-title":"Determinants of duration and mean rate of ventricular ejection","volume":"6","author":"Braunwald, E.; Sarnoff, S.J.; Stainsby, W.N.","year":"1958","unstructured":"Braunwald, E., Sarnoff, S. J., and Stainsby, W. N. (1958). Determinants of duration and mean rate of ventricular ejection. Circulation Research, 6, 3I9.","journal-title":"Circulation Research"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1172\/JCI105282","article-title":"Effects of beta-adrenergic blockade on the cardiac response to maximal and submaximal exercise in man","volume":"44","author":"Epstein, S.E.; Robinson, B.F.; Kahler, R.L.; Braunwald, E.","year":"1965","unstructured":"Epstein, S. E., Robinson, B. F., Kahler, R. L., and Braunwald, E. 1965. Effects of beta-adrenergic blockade on the cardiac response to maximal and submaximal exercise in man. Journal of Clinical Investigation, 44, 1745.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_5","article-title":"Propranolol hydrochloride in the treatment of angina pectoris","author":"Ginn, W.M.; Orgain, E.S.","year":"1966","unstructured":"Ginn, W. M., and Orgain, E. S. 1966. Propranolol hydrochloride in the treatment of angina pectoris. Journal of the American Medical Association, 198, 1214.","journal-title":"Journal of the American Medical Association"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1172\/JCI104469","article-title":"Studies on the first derivative of the ventricular pressure pulse in man","volume":"41","author":"Gleason, W. L.; Braunwald, E. 1962","unstructured":"Gleason, W. L., and Braunwald, E. 1962. Studies on the first derivative of the ventricular pressure pulse in man. Journal of Clinical Investigation, 41, 80.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_7","first-page":"36","article-title":"Multicenter trial of propranolol in angina pectoris","volume":"12","author":"Grant, R.H.E.; Keelan, P.; Kernohan, R.J.; Leonard, J.C.; Nancekievill, L.; Sinclair, K.","year":"1966","unstructured":"Grant, R. H. E., Keelan, P., Kernohan, R. J., Leonard, J. C., Nancekievill, L., and Sinclair, K. 1966. Multicenter trial of propranolol in angina pectoris. American Journal of Cardiology, 12, 36I.","journal-title":"American Journal of Cardiology"},{"key":"ref_8","first-page":"6","article-title":"Continuous electrocardiographic recording in Prinzmetal's variant angina pectoris. A report of four cases","volume":"32","author":"Guazzi, M.; Fiorentini, C.; Polese, A.; Magrini, F.","year":"1970","unstructured":"Guazzi, M., Fiorentini, C., Polese, A., and Magrini, F. 1970. Continuous electrocardiographic recording in Prinzmetal's variant angina pectoris. A report of four cases. British Heart Journal, 32, 6ii.","journal-title":"British Heart Journal"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/hrt.33.1.84","article-title":"Left ventricular performance and related haemodynamic changes in Prinzmetal's variant angina pectoris","volume":"33","author":"Guazzi, M.; Polese, A.; Fiorentini, C.; Magrini, F.; Bartorelli, C.","year":"1971","unstructured":"Guazzi, M., Polese, A., Fiorentini, C., Magrini, F., and Bartorelli, C. 1971. Left ventricular performance and related haemodynamic changes in Prinzmetal's variant angina pectoris. British Heart journal, 33, 84.","journal-title":"British Heart journal"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1136\/hrt.27.6.892","article-title":"Cardiac output after beta-adrenergic blockade in ischaemic heart disease","volume":"27","author":"Hamer, J.; Sowton, E.","year":"1965","unstructured":"Hamer, J., and Sowton, E. 1965. Cardiac output after beta-adrenergic blockade in ischaemic heart disease. British Heart Journal, 27, 892.","journal-title":"British Heart Journal"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/0002-9149(66)90053-1","article-title":"Effects of propranolol on exercise tolerance in angina pectoris","volume":"8","author":"Hamer, J.; Sowton, E.","year":"1966","unstructured":"Hamer, J., and Sowton, E. 1966. Effects of propranolol on exercise tolerance in angina pectoris. American Journal of Cardiology, I8, 354.","journal-title":"American Journal of Cardiology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/bmj.1.5439.897","article-title":"Double-blind trial of propranolol (Inderal) in angina pectoris","volume":"7","author":"Keelan, P.","year":"1965","unstructured":"Keelan, P. 1965. Double-blind trial of propranolol (Inderal) in angina pectoris. British Medical Journal, 7, 897.","journal-title":"British Medical Journal"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/j.1476-5381.1965.tb01719.x","article-title":"The effects on cardiac muscle of P-receptor antagonists in relation to their activity as local anaesthetics","volume":"24","unstructured":"The effects on cardiac muscle of P-receptor antagonists in relation to their activity as local anaesthetics. British Journal of Pharmacology and Chemotherapy, 24, 332.","journal-title":"British Journal of Pharmacology and Chemotherapy"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1152\/ajplegacy.1966.210.4.833","article-title":"Effect of beta adrenergic blockade on the cardiovascular dynamics","volume":"210","author":"Nakano, J.; Kusakari, T.","year":"1966","unstructured":"Nakano, J., and Kusakari, T. 1966. Effect of beta adrenergic blockade on the cardiovascular dynamics. American Journal of Physiology, 210, 833.","journal-title":"American Journal of Physiology"},{"key":"ref_15","first-page":"II.","article-title":"1968. Hemodynamic effects of propranolol in coronary heart disease","volume":"2","author":"Parker, J.O.; West, R.O.; Di Giorgi, S.","unstructured":"Parker, J. O., West, R. O., and Di Giorgi, S. 1968. Hemodynamic effects of propranolol in coronary heart disease. American Journal of Cardiology, 2I, II.","journal-title":"American Journal of Cardiology"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0002-9343(59)90003-8","article-title":"A variant form of angina pectoris","volume":"27","unstructured":"Prinzmetal, M., Kennamer, R., Merliss, R., Wada, T., and Bor, N. 1959. Angina pectoris. I. A variant form of angina pectoris. American Journal of Medicine, 27, 375.","journal-title":"American Journal of Medicine"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1172\/JCI105312","article-title":"Effects of exercise on myocardial force-velocity relations in intact unanesthetized man: relative roles of changes in heart rate, sympathetic activity, and ventricular dimensions","volume":"44","author":"Sonnenblick, E.H.; Braunwald, E.; Williams, J.F.; Glick, G.","year":"1965","unstructured":"Sonnenblick, E. H., Braunwald, E., Williams, J. F., and Glick, G. 1965. Effects of exercise on myocardial force-velocity relations in intact unanesthetized man: relative roles of changes in heart rate, sympathetic activity, and ventricular dimensions. Journal of Clinical Investigation, 44, 2051.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_18","first-page":"345","article-title":"Propranolol and angina pectoris","volume":"8","author":"Wolfson, S.; Heinle, R.A.; Herman, M.V.; Kemp, H.G.; Sullivan, J.M.; Gorlin, R.","year":"1966","unstructured":"Wolfson, S., Heinle, R. A., Herman, M. V., Kemp, H. G., Sullivan, J. M., and Gorlin, R. 1966. Propranolol and angina pectoris. American Journal of Cardiology, i8, 345.","journal-title":"American Journal of Cardiology"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.33.6.889","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:40:35Z","timestamp":1601080835000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.33.6.889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,11,1]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1971,11,1]]}},"URL":"https:\/\/doi.org\/10.1136\/hrt.33.6.889","relation":{},"ISSN":["1355-6037"],"issn-type":[{"value":"1355-6037","type":"print"}],"subject":[],"published":{"date-parts":[[1971,11,1]]}}}