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An accurate clinical diagnosis was established in only 17 per cent of a large group of cases of syphilitic aortitis reviewed in a clinicopathological necropsy study (Heggtveit, 1964)","year":"1965","unstructured":"Syphilitic cardiovascular disease occurs more frequently than is recognised clinically. An accurate clinical diagnosis was established in only 17 per cent of a large group of cases of syphilitic aortitis reviewed in a clinicopathological necropsy study (Heggtveit, 1964). Beck et al. (1965) emphasised the importance of suspecting syphilitic ostial occlusion when angina is disproportionate in the presence of aortic regurgitation, but in this patient there was no history of angina pectoris and no clinical or necropsy evidence of aortic valve involvement. In Bruenn's series (1934) 62-5 per cent of cases with stenosed coronary ostia experienced cardiac pain, the inference being that the absence of angina pectoris does not rule out the presence of such stenosis.","journal-title":"Beck et al; Bruenn's series; emphasised the importance of suspecting syphilitic ostial occlusion when angina is disproportionate in the presence of aortic regurgitation, but in this patient there was no history of angina pectoris and no clinical or necropsy evidence of aortic valve involvement"},{"key":"ref_2","article-title":"patients with luetic aortitis will have hearts which display some degree of interstitial fibrosis of the myocardium (Heggtveit, 1964). It is uncertain whether myocardial fibrosis in these cases results from ostial stenosis, or whether it is due to syphilitic myocarditis or coexistent coronary atherosclerosis","author":"Virtually all","unstructured":"Virtually all patients with luetic aortitis will have hearts which display some degree of interstitial fibrosis of the myocardium (Heggtveit, 1964). It is uncertain whether myocardial fibrosis in these cases results from ostial stenosis, or whether it is due to syphilitic myocarditis or coexistent coronary atherosclerosis. It seems likely that the subendocardial"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1136\/hrt.27.6.911","article-title":"Syphilitic obstruction of coronary ostia successfully treated by endarterectomy","volume":"27","author":"Beck, W.; Barnard, C.N.; Schrire, V.","year":"1965","unstructured":"Beck, W., Barnard, C. N., and Schrire, V. (1965). Syphilitic obstruction of coronary ostia successfully treated by endarterectomy. British Heart J'ournal, 27, 911.","journal-title":"British Heart J'ournal"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0002-8703(34)90091-0","article-title":"Syphilitic disease of the coronary arteries","volume":"9","author":"Bruenn, H.G.","year":"1934","unstructured":"Bruenn, H. G. (1934). Syphilitic disease of the coronary arteries. American Heart Journal, 9, 421.","journal-title":"American Heart Journal"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1161\/01.CIR.29.3.346","article-title":"Syphilitic aortitis. A clinicopathologic autopsy study of 100 cases, 1950-1960","volume":"29","author":"Heggtveit, H.A.","year":"1964","unstructured":"Heggtveit, H. A. (1964). Syphilitic aortitis. A clinicopathologic autopsy study of 100 cases, 1950-1960. Circulation, 29, 346.","journal-title":"Circulation"},{"key":"ref_6","first-page":"154","article-title":"Observations upon syphilis of the heart, coronary ostia and coronary arteries","volume":"18","author":"Love, Jr., W.S.; Warner, C.G.","year":"1934","unstructured":"Love, W. S., Jr., and Warner, C. G. (1934). Observations upon syphilis of the heart, coronary ostia and coronary arteries. American Journal of Syphilis and Neurology, 18, 154.","journal-title":"American Journal of Syphilis and Neurology"},{"issue":"152","key":"ref_7","article-title":"Clinical recognition of the cardiomyopathies","volume":"35","author":"Oakley, C.M.","year":"1974","unstructured":"Oakley, C. M. (1974). Clinical recognition of the cardiomyopathies. Circulation Research, 35, Suppl. II, 152.","journal-title":"Circulation Research"},{"key":"ref_8","article-title":"Observations on 107 cases of syphilitic aortic insufficiency with special reference to aortic valve area, myocardium and branches of the aorta","author":"Saphir, O.; Scott, R.W.","year":"1930","unstructured":"Saphir, O., and Scott, R. W. (1930). Observations on 107 cases of syphilitic aortic insufficiency with special reference to aortic valve area, myocardium and branches of the aorta."},{"key":"ref_9","first-page":"553","article-title":"Syphilitic coronary ostial occlusion","volume":"40","author":"Schrire, V.; Barnard, C.N.; Beck, W.","year":"1966","unstructured":"Schrire, V., Barnard, C. N., and Beck, W. (1966). Syphilitic coronary ostial occlusion. South African Medical journal, 40, 553.","journal-title":"South African Medical journal"},{"key":"ref_10","first-page":"483","article-title":"The electrocardiogram in syphilitic heart disease","volume":"20","author":"Storey, G.","year":"1958","unstructured":"Storey, G. (1958). The electrocardiogram in syphilitic heart disease. British Hcart J7ournal, 20, 483.","journal-title":"British Hcart J7ournal"},{"key":"ref_11","first-page":"115","article-title":"Syphilis of medium and smaller arteries","volume":"69","author":"Warthin, A.S.","year":"1922","unstructured":"Warthin, A. S. (1922). Syphilis of medium and smaller arteries. New York Medical J7ournal, 69, 115.","journal-title":"New York Medical J7ournal"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.39.4.469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:48:06Z","timestamp":1601081286000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.39.4.469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,4,1]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1977,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/hrt.39.4.469","relation":{},"ISSN":["1355-6037"],"issn-type":[{"value":"1355-6037","type":"print"}],"subject":[],"published":{"date-parts":[[1977,4,1]]}}}