{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:01:24Z","timestamp":1787497284627,"version":"build-2736575974"},"reference-count":32,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[1983,12,1]]},"DOI":"10.1136\/hrt.50.6.540","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:46:00Z","timestamp":1190137560000},"page":"540-549","source":"Crossref","is-referenced-by-count":12,"title":["Left ventricular function in persistent pulmonary hypertension of the newborn. Computer analysis of the echocardiogram."],"prefix":"10.1136","volume":"50","author":[{"given":"M G","family":"St John Sutton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R A","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"issue":"28","key":"ref_1","first-page":"28","article-title":"Pulmonary vascular adjustments in the neonatal period","volume":"1961","author":"Rudolph, A.M.; Auld, P.A.M.; Golinko, R.J.; Paul, M.H.","unstructured":"Rudolph AM, Auld PAM, Golinko RJ, Paul MH. Pulmonary vascular adjustments in the neonatal period. Pediatrics 1961; 28: 28-34.","journal-title":"Pediatrics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0022-3476(64)80395-4","article-title":"Pulmonary arterial pressure changes in human newborn infants from birth to 3 days of age","volume":"65","author":"Emmanouilides, G.C.; Moss, A.J.; ER, Jr, Duffie; Adams, F.H.","year":"1964","unstructured":"Emmanouilides GC, Moss AJ, Duffie ER Jr, Adams FH. Pulmonary arterial pressure changes in human newborn infants from birth to 3 days of age. J Pediatr 1964; 65: 327-33.","journal-title":"J Pediatr"},{"issue":"40","key":"ref_3","article-title":"C.' syndrome (persistence of the fetal circulation","volume":"1969","author":"Abstract","unstructured":"Gersony WM, Duc GV, Sinclai; JC. 'P.F.C.' syndrome (persistence of the fetal circulation. [Abstract]. Circulation 1969; 40 (suppl III): 87.","journal-title":"Circulation"},{"key":"ref_4","first-page":"62630","article-title":"Persistent pulmonary hypertension of the newborn infant","volume":"89","author":"Levin, D.L.; Heymann, M.A.; Kitterman, J.A.; Gregory, G.A.; Phibbs, R.H.; Rudolph, A.M.","year":"1976","unstructured":"Levin DL, Heymann MA, Kitterman JA, Gregory GA, Phibbs RH, Rudolph AM. Persistent pulmonary hypertension of the newborn infant. J Pediatr 1976; 89: 62630.","journal-title":"J Pediatr"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0022-3476(71)80462-6","article-title":"Persistent pulmonary vascular obstruction in newborn infants","volume":"78","author":"Siassi, B.; Goldberg, S.J.; Emmanouilides, G.C.; Higashino, S.M.; Lewis, E.","year":"1971","unstructured":"Siassi B, Goldberg SJ, Emmanouilides GC, Higashino SM, Lewis E. Persistent pulmonary vascular obstruction in newborn infants. J Pediatr 1971; 78: 610-5.","journal-title":"J Pediatr"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0022-3476(77)80521-0","article-title":"Persistence of fetal circulation syndrome: an echocardiographic study","volume":"91","author":"Riggs, T.; Hirschfeld, S.; Fanaroff, A.; Liebman, H.; Fletcher, B.; Meyer, R.A.","year":"1977","unstructured":"Riggs T, Hirschfeld S, Fanaroff A, Liebman H, Fletcher B, Meyer RA. Persistence of fetal circulation syndrome: an echocardiographic study.J Pediatr 1977; 91: 626-31.","journal-title":"J Pediatr"},{"key":"ref_7","first-page":"243","article-title":"Transient myocardial ischemia of the newborn infant: a form of severe cardiorespiratory distress in full-term infants.y Pediatr","volume":"81","author":"Rowe, R.D.; Hoffman, T.","year":"1972","unstructured":"Rowe RD, Hoffman T. Transient myocardial ischemia of the newborn infant: a form of severe cardiorespiratory distress in full-term infants.y Pediatr 1972; 81: 243-50."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0022-3476(76)80404-0","article-title":"Disturbances of the transitional circulation: spectrum of pulmonary hypertension and myocardial dysfunction","volume":"89","author":"Riemenschneider, T.A.; Nielsen, H.C.; Ruttenberg, H.D.; Jaffe, R.B.","year":"1976","unstructured":"Riemenschneider TA, Nielsen HC, Ruttenberg HD, Jaffe RB. Disturbances of the transitional circulation: spectrum of pulmonary hypertension and myocardial dysfunction. J Pediatr 1976; 89: 622-5.","journal-title":"J Pediatr"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1136\/hrt.35.11.1141","article-title":"Measurement of instantaneous left ventricular dimension and filling rate in man using echocardiography","volume":"35","author":"Gibson, D.G.; Brown, D.","year":"1973","unstructured":"Gibson DG, Brown D. Measurement of instantaneous left ventricular dimension and filling rate in man using echocardiography. Br Heart J 1973; 35: 1141-9.","journal-title":"Br Heart J"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1161\/01.CIR.57.6.1198","article-title":"Cardiac function in the normal newborn-additional information by computer analysis of the M-mode echocardiogram","volume":"57","author":"MG, St John Sutton; DJ, Hagler; AJ, Tajik; ER, Giuliani; JB, Seward; DG, Ritter; EL, Ritman","year":"1978","unstructured":"St John Sutton MG, Hagler DJ, Tajik AJ, Giuliani ER, Seward JB, Ritter DG, Ritman EL. Cardiac function in the normal newborn-additional information by computer analysis of the M-mode echocardiogram. Circulation 1978; 57: 1198-204.","journal-title":"Circulation"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1136\/hrt.48.4.342","article-title":"Effect of age related changes in chamber size, wall thickness, and heart rate on left ventricular function in normal children","volume":"48","author":"MG, St John Sutton; DL, Marier; PJ, Oldershaw; R, Sacchetti; DG, Gibson","year":"1982","unstructured":"St John Sutton MG, Marier DL, Oldershaw PJ, Sacchetti R, Gibson DG. Effect of age related changes in chamber size, wall thickness, and heart rate on left ventricular function in normal children. Br HeartJ 1982; 48: 342-51.","journal-title":"Br HeartJ"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1161\/01.CIR.57.3.512","article-title":"Echocardiographic assessment of left ventricular filling and septal and posterior wall dynamics in idiopathic hypertrophic subaortic stenosis","volume":"57","author":"MG, St John Sutton; AJ, Tajik; DG, Gibson; DJ, Brown; JB, Seward; ER, Giuliani","year":"1978","unstructured":"St John Sutton MG, Tajik AJ, Gibson DG, Brown DJ, Seward JB, Giuliani ER. Echocardiographic assessment of left ventricular filling and septal and posterior wall dynamics in idiopathic hypertrophic subaortic stenosis. Circulation 1978; 57: 512-20.","journal-title":"Circulation"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1136\/hrt.41.1.54","article-title":"Echocardiographic features of secondary left ventricular hypertrophy","volume":"41","author":"Gibson, D.G.; Trail, T.A.; Hall, R.J.C.; Brown, D.J.","year":"1979","unstructured":"Gibson DG, Trail TA, Hall RJC, Brown DJ. Echocardiographic features of secondary left ventricular hypertrophy. Br Heart J 1979; 41: 54-9.","journal-title":"Br Heart J"},{"key":"ref_14","article-title":"Effects of age, body size and blood pressure on the normal human left ventricle","author":"MG, St John Sutton; N, Reichek; J, Lovett; JA, Kastor; ER, Giuliani","year":"1980","unstructured":"St John Sutton MG, Reichek N, Lovett J, Kastor JA, Giuliani ER. Effects of age, body size and blood pressure on the normal human left ventricle [Abstract]. Circulation 1980; 62 (suppl III): 305.","journal-title":"Circulation"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/0002-9149(79)90182-6","article-title":"Increased systemic vascular resistance in neonates with pulmonary hypertension","volume":"44","author":"Milstein, J.M.; Goetzman, B.W.; Riemenschneider, T.A.; Wennberg, R.P.","year":"1979","unstructured":"Milstein JM, Goetzman BW, Riemenschneider TA, Wennberg RP. Increased systemic vascular resistance in neonates with pulmonary hypertension. Am J Cardiol 1979; 44: 1159-62.","journal-title":"Am J Cardiol"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1161\/01.CIR.48.4.801","article-title":"An appraisal of mitral valve echocardiograms mimicking mitral stenosis in conditions with right ventricular pressure overload","volume":"48","author":"McLaurin, L.P.; Gibson, T.C.; Waider, W.; Grossman, W.; Craige, E.","year":"1973","unstructured":"McLaurin LP, Gibson TC, Waider W, Grossman W, Craige E. An appraisal of mitral valve echocardiograms mimicking mitral stenosis in conditions with right ventricular pressure overload. Circulation 1973; 48: 801-9.","journal-title":"Circulation"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/0002-9149(78)90872-X","article-title":"Left ventricular function in chronic pulmonary hypertension","volume":"41","year":"1978","unstructured":"Krayenbuehl HP, Turina J, Hess 0. Left ventricular function in chronic pulmonary hypertension. Am J Cardiol 1978; 41: 1150-8.","journal-title":"Am J Cardiol"},{"key":"ref_18","first-page":"491","volume":"85","author":"HeartJ, Am","year":"1973","unstructured":"Am HeartJ 1973; 85: 491-500."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1161\/01.CIR.60.5.1082","article-title":"Assessment of left ventricular function in secundum atrial septal defect by computer analysis of the M-mode echocardiogram","volume":"60","author":"MG, St John Sutton; AJ, Tajik; L-A, Mercier; JB, Seward; ER, Giuliani; EL, Ritman","year":"1979","unstructured":"St John Sutton MG, Tajik AJ, Mercier L-A, Seward JB, Giuliani ER, Ritman EL. Assessment of left ventricular function in secundum atrial septal defect by computer analysis of the M-mode echocardiogram. Circulation 1979; 60: 1082-90.","journal-title":"Circulation"},{"issue":"2","key":"ref_20","first-page":"327","article-title":"The effect of chronic pulmonary hypertension on left ventricular size and dynamics","volume":"66","author":"Likoff, M.J.; St John Sutton, M.G.; Weber, K.T.; Janicki, J.S.; Reichek, N.","year":"1982","unstructured":"Likoff MJ, St John Sutton MG, Weber KT, Janicki JS, Reichek N. The effect of chronic pulmonary hypertension on left ventricular size and dynamics [Abstract]. Circulation 1982; 66 (suppl 2): 327.","journal-title":"Circulation"},{"key":"ref_21","first-page":"873","article-title":"Coronary circulation","volume-title":"ofphysiology, Section 2. The cardiovascular system","author":"Berne, R.M.; Rubio, R.","year":"1979","unstructured":"Berne RM, Rubio R. Coronary circulation. In: Berne RM, Sprakelakis N, eds. Handbook ofphysiology, Section 2. The cardiovascular system. Baltimore: Williams and Wilkins, 1979: 873-9."},{"issue":"30","key":"ref_22","first-page":"902","article-title":"The effects of prolonged neonatal hypoxemia on the pulmonary vascular bed and heart","volume":"1962","author":"Naeye, R.L.; Letts, H.W.","unstructured":"Naeye RL, Letts HW. The effects of prolonged neonatal hypoxemia on the pulmonary vascular bed and heart. Pediatrics 1962; 30: 902-8.","journal-title":"Pediatrics"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0022-3476(68)80106-4","article-title":"Myocardial infarcts in infants and children: 1. A necropsy study in congenital heart disease","volume":"73","author":"Franciosi, R.A.; Blanc, W.A.","year":"1968","unstructured":"Franciosi RA, Blanc WA. Myocardial infarcts in infants and children: 1. A necropsy study in congenital heart disease. J Pediatr 1968; 73: 309-19.","journal-title":"J Pediatr"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1542\/peds.39.6.896","article-title":"Some aspects of cardiac pathology in infancy and childhood. IV. Myocardial and coronary lesions in cardiac malformations","volume":"39","author":"Esterly, JR, Oppenheimer; E.H.","year":"1967","unstructured":"Esterly JR, Oppenheimer EH. Some aspects of cardiac pathology in infancy and childhood. IV. Myocardial and coronary lesions in cardiac malformations. Pediatrics 1967; 39: 896-903.","journal-title":"Pediatrics"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/S0022-3476(59)80261-4","article-title":"Myocardial infarction in the perinatal period","volume":"55","author":"Richard, R.; Benirschke, K.","year":"1959","unstructured":"Richard R, Benirschke K. Myocardial infarction in the perinatal period. J Pediatr 1959; 55: 706-12.","journal-title":"J Pediatr"},{"key":"ref_26","first-page":"1217","article-title":"Left ventricular myocardial infarction in tetralogy of Fallot","volume":"132","author":"Mehran-Pour, M.; Hirschfeld, S.; Francioli, M.; Liebman, J.","year":"1978","unstructured":"Mehran-Pour M, Hirschfeld S, Francioli M, Liebman J. Left ventricular myocardial infarction in tetralogy of Fallot. Am J Dis Child 1978; 132: 1217-8.","journal-title":"Am J Dis Child"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0022-3476(80)80832-8","article-title":"Papillary muscle necrosis in a neonatal autopsy population: incidence and associated clinical manifestations","volume":"96","author":"Setzer, E.; Ermocilla, R.; Tonkin, I.; John, E.; Sansa, M.; Cassady, G.","year":"1980","unstructured":"Setzer E, Ermocilla R, Tonkin I, John E, Sansa M, Cassady G. Papillary muscle necrosis in a neonatal autopsy population: incidence and associated clinical manifestations. J Pediatr 1980; 96: 289-94.","journal-title":"J Pediatr"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0022-3476(80)80833-X","article-title":"Ischemic papillary muscle necrosis in stressed newborn infants","volume":"96","author":"Donnelly, W.H.; Bucciarelli, R.L.; Nelson, R.M.","year":"1980","unstructured":"Donnelly WH, Bucciarelli RL, Nelson RM. Ischemic papillary muscle necrosis in stressed newborn infants. J Pediatr 1980; 96: 295-300.","journal-title":"J Pediatr"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0022-3476(79)80841-0","article-title":"Transient myocardial ischemia of the newborn infant demonstrated by thallium myocardial imaging","volume":"94","author":"Finley, J.P.; Howman-Giles, R.B.; Gilday, D.L.; Bloom, K.R.; Rowe, R.D.","year":"1979","unstructured":"Finley JP, Howman-Giles RB, Gilday DL, Bloom KR, Rowe RD. Transient myocardial ischemia of the newborn infant demonstrated by thallium myocardial imaging. Pediatr 1979; 94: 263-70.","journal-title":"Pediatr"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1172\/JCI105355","article-title":"Response of the pulmonary vasculature to hypoxia and H+ ion concentration changes","volume":"45","author":"Rudolph, A.M.; Yuan, S.","year":"1966","unstructured":"Rudolph AM, Yuan S. Response of the pulmonary vasculature to hypoxia and H+ ion concentration changes. Clin Invest 1966; 45: 399-411.","journal-title":"Clin Invest"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1172\/JCI104999","article-title":"The influence of hydrogen ion concentration and hypoxia on the pulmonary circulation","volume":"43","author":"Enson, Y.; Giuntine, C.; Lewis, M.L.; Morris, T.Q.; Ferrer, M.I.; Harvey, R.N.","year":"1964","unstructured":"Enson Y, Giuntine C, Lewis ML, Morris TQ, Ferrer MI, Harvey RN. The influence of hydrogen ion concentration and hypoxia on the pulmonary circulation. Clin Invest 1964; 43: 1146-62.","journal-title":"Clin Invest"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1152\/ajplegacy.1966.210.6.1327","article-title":"The influences of hypoxemia and acidemia on left ventricular function","volume":"210","author":"Downing, S.E.; Talner, N.S.; Gardner, T.H.","year":"1966","unstructured":"Downing SE, Talner NS, Gardner TH. The influences of hypoxemia and acidemia on left ventricular function. Am Physiol 1966; 210: 1327-34.","journal-title":"Am Physiol"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.50.6.540","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T18:39:02Z","timestamp":1708195142000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.50.6.540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,12,1]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1983,12,1]]}},"URL":"https:\/\/doi.org\/10.1136\/hrt.50.6.540","relation":{},"ISSN":["1355-6037"],"issn-type":[{"value":"1355-6037","type":"print"}],"subject":[],"published":{"date-parts":[[1983,12,1]]}}}