{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:58:40Z","timestamp":1761058720882},"reference-count":33,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[1992,12,1]]},"DOI":"10.1136\/hrt.68.12.567","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:46:00Z","timestamp":1190151960000},"page":"567-573","source":"Crossref","is-referenced-by-count":21,"title":["Relation of left ventricular isovolumic relaxation time and incoordination to transmitral Doppler filling patterns"],"prefix":"10.1136","volume":"68","author":[{"given":"S. J D","family":"Brecker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. H","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. G","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"181","article-title":"Assessment of diastolic function of the heart: background and current applications of Doppler echocardiography. Part II","volume-title":"Clinical studies. Mayo Clin Proc 1989; 64","author":"Nishimura, R.A.; Abel, M.D.; Hatle, L.K.; Tajik, A.J.","unstructured":"Nishimura RA, Abel MD, Hatle LK, Tajik AJ. Assessment of diastolic function of the heart: background and current applications of Doppler echocardiography. Part II. Clinical studies. Mayo Clin Proc 1989;64:181-204."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1540-8175.1986.tb00182.x","article-title":"Doppler echocardiographic approaches to ventricular diastolic function","volume":"3","author":"Danford, D.A.; Huhta, J.C.; DJ, Jr, Murphy","year":"1986","unstructured":"Danford DA, Huhta JC, Murphy DJ Jr. Doppler echocardiographic approaches to ventricular diastolic function. Echocardiography 1986;3:33-40.","journal-title":"Echocardiography"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/0002-9149(84)90035-3","article-title":"Augmentation ofatrial contribution to left ventricular inflow with aging as assessed by intracardiac Doppler flowmetry","volume":"53","author":"Miyatake, K.; Okamoto, M.; Kinoshita, N.","year":"1984","unstructured":"Miyatake K, Okamoto M, Kinoshita N, et al. Augmentation ofatrial contribution to left ventricular inflow with aging as assessed by intracardiac Doppler flowmetry. AmJ Cardiol 1984;53:586-9.","journal-title":"AmJ Cardiol"},{"key":"ref_4","first-page":"1005","article-title":"Estimation of left ventricular end-diastolic pressure by pulsed Doppler ultrasound","volume":"i:","author":"Channer, K.S.; Culling, W.; Wilde, P.; Jones, J.V.","year":"1986","unstructured":"Channer KS, Culling W, Wilde P, Jones JV. Estimation of left ventricular end-diastolic pressure by pulsed Doppler ultrasound. Lancet 1986;i:1005-7.","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/0002-8703(88)90153-6","article-title":"Determination of left ventricular filling parameters by pulsed Doppler echocardiography: a noninvasive method to predict high filling pressures in patients with coronary artery disease","volume":"116","author":"Kuecherer, H.; Ruffmann, K.; Kuebler, W.","year":"1988","unstructured":"Kuecherer H, Ruffmann K, Kuebler W. Determination of left ventricular filling parameters by pulsed Doppler echocardiography: a noninvasive method to predict high filling pressures in patients with coronary artery disease. Am HeartJ 1988;116:1017-21.","journal-title":"Am HeartJ"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/0002-8703(89)90017-3","article-title":"Significance of Doppler indices of diastolic filling of the left ventricle: Comparison with invasive hemodynamics in a canine model","volume":"118","author":"Nishimura, R.A.; Abel, M.D.; Hatle, L.K.","year":"1989","unstructured":"Nishimura RA, Abel MD, Hatle LK, et al. Significance of Doppler indices of diastolic filling of the left ventricle: Comparison with invasive hemodynamics in a canine model. Am HeartJ 1989;118:1248-58.","journal-title":"Am HeartJ"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1161\/01.CIR.79.6.1226","article-title":"Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler echocardiography in humans","volume":"79","author":"Stoddard, M.F.; Pearson, A.C.; Kem, M.J.; Ratcliff, J.; Mrosek, D.G.; Labovitz, A.J.","year":"1989","unstructured":"Stoddard MF, Pearson AC, Kem MJ, Ratcliff J, Mrosek DG, Labovitz AJ. Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler echocardiography in humans. Circulation 1989;79: 1226-36.","journal-title":"Circulation"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0002-8703(91)90770-I","article-title":"Early left ventricular filling: An approach to its multifactorial nature using a combined hemodynamic-Doppler technique","volume":"122","author":"Marino, P.; Destro, G.; Barbieri, E.; Zardini, P.","year":"1991","unstructured":"Marino P, Destro G, Barbieri E, Zardini P. Early left ventricular filling: An approach to its multifactorial nature using a combined hemodynamic-Doppler technique. Am Heart J 1991;122:132-41.","journal-title":"Am Heart J"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1161\/01.CIR.74.1.187","article-title":"Left ventricular fillingdynamics: influenceofleft ventricular relaxation and left atrial pressure","volume":"74","author":"Ishida, Y.; Meisner, J.S.; Tsujioka, K.","year":"1986","unstructured":"Ishida Y, Meisner JS, Tsujioka K, et al. Left ventricular fillingdynamics: influenceofleft ventricular relaxation and left atrial pressure. Circulation 1986;74.:187-96.","journal-title":"Circulation"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1161\/01.CIR.78.3.672","article-title":"Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography","volume":"78","author":"Choong, C.Y.; Abascal, V.M.; Thomas, J.D.; Guerrero, J.L.; McGlew, S.; Weyman, A.E.","year":"1988","unstructured":"Choong CY, Abascal VM, Thomas JD, Guerrero JL, McGlew S, Weyman AE. Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography. Circulation 1988;78:672-83.","journal-title":"Circulation"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/0002-8703(89)90230-5","article-title":"The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile","volume":"118","author":"Takagi, S.; Tokota, M.; Iwase, M.","year":"1989","unstructured":"Takagi S, Tokota M, Iwase M, et al. The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile. Am Heart J 1989; 118:954-62.","journal-title":"Am Heart J"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0735-1097(89)90507-X","article-title":"Left ventricular diastolic function: Comparison of pulsed Doppler echocardiographic and hemodynamic indexes in subjects with and without coronary artery disease","volume":"13","author":"Stoddard, M.F.; Pearson, A.C.; Kem, M.J.; Ratcliff, J.; Mrosek, D.G.; Labovitz, A.J.","year":"1989","unstructured":"Stoddard MF, Pearson AC, Kem MJ, Ratcliff J, Mrosek DG, Labovitz AJ. Left ventricular diastolic function: Comparison of pulsed Doppler echocardiographic and hemodynamic indexes in subjects with and without coronary artery disease. J Am Coll Cardiol 1989;13:327-36.","journal-title":"J Am Coll Cardiol"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/0735-1097(91)90799-F","article-title":"Importance of left ventricular systolic function in the assessment of left ventricular diastolic function with Doppler transmitral flow velocity recording","volume":"18","author":"Himura, Y.; Kumada, T.; Kambayashi, M.","year":"1991","unstructured":"Himura Y, Kumada T, Kambayashi M, et al. Importance of left ventricular systolic function in the assessment of left ventricular diastolic function with Doppler transmitral flow velocity recording. JAm Coll Cardiol 1991;18:753-60.","journal-title":"JAm Coll Cardiol"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1136\/hrt.65.4.194","article-title":"Diastolic disease in left ventricular hypertrophy: comparison of M mode and Doppler echocardiography for the assessment of rapid ventricular filling","volume":"65","author":"Lee, C.H.; Hogan, J.C.; Gibson, D.G.","year":"1991","unstructured":"Lee CH, Hogan JC, Gibson DG. Diastolic disease in left ventricular hypertrophy: comparison of M mode and Doppler echocardiography for the assessment of rapid ventricular filling. Br Heart J 1991;65:194-200.","journal-title":"Br Heart J"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/hrt.39.6.661","article-title":"Left ventricular filling in hypertrophic cardiomyopathy. An angiographic study","volume":"39","author":"Sanderson, J.E.; Gibson, D.G.; Brown, D.J.; Goodwin, J.F.","year":"1977","unstructured":"Sanderson JE, Gibson DG, Brown DJ, Goodwin JF. Left ventricular filling in hypertrophic cardiomyopathy. An angiographic study. Br Heart J 1977;39:661-70.","journal-title":"Br Heart J"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0002-9149(80)90058-2","article-title":"Interaction of left ventricular relaxation and filling during early diastole in human subjects","volume":"46","author":"Fioretti, P.; Brower, R.W.; Meester, G.T.; Serruys, P.W.","year":"1980","unstructured":"Fioretti P, Brower RW, Meester GT, Serruys PW. Interaction of left ventricular relaxation and filling during early diastole in human subjects. Am J Cardiol 1980;46: 197-203.","journal-title":"Am J Cardiol"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1136\/hrt.35.11.1141","article-title":"Measurement of instantaneous left ventricular dimension and filling rate in man, using echocardiography","volume":"35","author":"Gibson, D.G.; Brown, D.","year":"1973","unstructured":"Gibson DG, Brown D. Measurement of instantaneous left ventricular dimension and filling rate in man, using echocardiography. Br Heart J 1973;35:1141-9.","journal-title":"Br Heart J"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/hrt.63.4.209","article-title":"Relation of filling pattern to diastolic function in severe left ventricular disease","volume":"63","author":"Ng, K.S.K.; Gibson, D.G.","year":"1990","unstructured":"Ng KSK, Gibson DG. Relation of filling pattern to diastolic function in severe left ventricular disease. Br Heart J 1990;63:209-14.","journal-title":"Br Heart J"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1136\/hrt.64.3.214","article-title":"Discrepancies in the measurement of isovolumic relaxation time: a study comparing M mode and Doppler echocardiography","volume":"64","author":"Lee, C.H.; Vancheri, F.; Josen, M.S.; Gibson, D.G.","year":"1990","unstructured":"Lee CH, Vancheri F, Josen MS, Gibson DG. Discrepancies in the measurement of isovolumic relaxation time: a study comparing M mode and Doppler echocardiography. Br Heart J 1990;64:214-8.","journal-title":"Br Heart J"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/hrt.50.4.362","article-title":"Mechanisms of reduced left ventricular filling rate in coronary artery disease","volume":"50","author":"Hui, W.K.K.; Gibson, D.G.","year":"1983","unstructured":"Hui WKK, Gibson DG. Mechanisms of reduced left ventricular filling rate in coronary artery disease. Br Heart J 1983;50:362-71.","journal-title":"Br Heart J"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1136\/hrt.47.3.253","article-title":"Non-invasive assessment of changes in left ventricular relaxation by combined phono-, echo-, and mechanocardiography","volume":"47","author":"Mattheos, M.; Shapiro, E.; Oldershaw, P.J.; Sacchetti, R.; Gibson, D.G.","year":"1982","unstructured":"Mattheos M, Shapiro E, Oldershaw PJ, Sacchetti R, Gibson DG. Non-invasive assessment of changes in left ventricular relaxation by combined phono-, echo-, and mechanocardiography. Br Heart J 1982;47:253-60.","journal-title":"Br Heart J"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1136\/hrt.38.10.1010","article-title":"Analysis of left ventricular wall movement during isovolumic relaxation and its relation to coronary artery disease","volume":"38","author":"Gibson, D.G.; Prewitt, T.A.; Brown, D.J.","year":"1976","unstructured":"Gibson DG, Prewitt TA, Brown DJ. Analysis of left ventricular wall movement during isovolumic relaxation and its relation to coronary artery disease. Br Heart J 1976;38: 1010-9.","journal-title":"Br Heart J"},{"key":"ref_23","first-page":"47","article-title":"Ventricular suction under zero source pressure for filling","volume":"251","year":"1986","unstructured":"Suga H, Goto Y, Igarashi Y, Yamada 0, Nozawa T, Yasumura Y. Ventricular suction under zero source pressure for filling. Am J Physiol 1986;251:47-55.","journal-title":"Am J Physiol"},{"key":"ref_24","first-page":"620","article-title":"Left ventricular relaxation in the filling and nonfilling intact canine heart","volume":"250","author":"Yellin, E.L.; Hori, M.; Yoran, C.; Sonnenblick, E.H.; Gabbay, S.; Frater, R.W.M.","year":"1986","unstructured":"Yellin EL, Hori M, Yoran C, Sonnenblick EH, Gabbay S, Frater RWM. Left ventricular relaxation in the filling and nonfilling intact canine heart. Am J Physiol 1986;250: 620-9.","journal-title":"Am J Physiol"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1161\/01.RES.62.6.1210","article-title":"Passive properties of canine left ventricle: diastolic stiffness and restoring forces","volume":"62","author":"Nikolic, S.; Yellin, E.L.; Tamura, K.","year":"1988","unstructured":"Nikolic S, Yellin EL, Tamura K, et al. Passive properties of canine left ventricle: diastolic stiffness and restoring forces. Circ Res 1988;62:1210-22.","journal-title":"Circ Res"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0167-5273(89)90014-4","article-title":"Phase differences between left ventricular wall motion and transmitral flow in man: evidence for involvement of ventricular restoring forces in normal rapid filling","volume":"24","author":"Park, C.H.; Chow, W.H.; Gibson, D.G.","year":"1989","unstructured":"Park CH, Chow WH, Gibson DG. Phase differences between left ventricular wall motion and transmitral flow in man: evidence for involvement of ventricular restoring forces in normal rapid filling. Int J Cardiol 1989;24:347-54.","journal-title":"Int J Cardiol"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1016\/0735-1097(90)92827-O","article-title":"Diastolic function in patients undergoing coronary angioplasty: Influence of degree of revascularisation","volume":"15","author":"Castello, R.; Pearson, A.C.; Kern, M.J.; Labovitz, A.J.; Lenzen, P.","year":"1990","unstructured":"Castello R, Pearson AC, Kern MJ, Labovitz AJ, Lenzen P. Diastolic function in patients undergoing coronary angioplasty: Influence of degree of revascularisation. J Am Coll Cardiol 1990;15:1564-9.","journal-title":"J Am Coll Cardiol"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0033-0620(90)90016-U","article-title":"Left ventricular filling dynamics and diastolic function","volume":"32","author":"Yellin, E.; Nikolic, S.; Frater, R.W.M.","year":"1990","unstructured":"Yellin E, Nikolic S, Frater RWM. Left ventricular filling dynamics and diastolic function. Prog Cardiovasc Dis 1990;32:247-7 1.","journal-title":"Prog Cardiovasc Dis"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1136\/hrt.40.4.367","article-title":"Detection of abnormal left ventricular wall movement during isovolumic contraction and early relaxation. Comparison of echo-and angiocardiography","volume":"40","author":"Doran, J.H.; Traill, T.A.; Brown, D.J.; Gibson, D.G.","year":"1978","unstructured":"Doran JH, Traill TA, Brown DJ, Gibson DG. Detection of abnormal left ventricular wall movement during isovolumic contraction and early relaxation. Comparison of echo-and angiocardiography. Br Heart J 1978;40:367-71.","journal-title":"Br Heart J"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1136\/hrt.40.7.758","article-title":"Abnormal left ventricular wall movement during early systole in patients with angina pectoris","volume":"40","author":"Gibson, D.G.; Doran, J.H.; Traill, T.A.; Brown, D.J.","year":"1978","unstructured":"Gibson DG, Doran JH, Traill TA, Brown DJ. Abnormal left ventricular wall movement during early systole in patients with angina pectoris. Br Heart J 1978;40:758-66.","journal-title":"Br Heart J"},{"key":"ref_31","article-title":"Prolonged right ventricular systole impairs left ventricular filling in pulmonary hypertension","volume":"394","author":"Brecker, S.J.; Stojnic, B.B.; Xiao, H.B.; Mbaissouroum, M.; Gibson, D.G.","year":"1992","unstructured":"Brecker SJ, Stojnic BB, Xiao HB, Mbaissouroum M, Gibson DG. Prolonged right ventricular systole impairs left ventricular filling in pulmonary hypertension [Abstract]. J Am Coll Cardiol 1992;19 (suppl A):394.","journal-title":"J Am Coll Cardiol"},{"key":"ref_32","article-title":"Modifications of the mitral flow due to the presence of a left bundle branch block","author":"Zelinsky, R.; Diebold, B.; Raffoul, H.; Cohen, A.","year":"1988","unstructured":"Zelinsky R, Diebold B, Raffoul H, Cohen A. Modifications of the mitral flow due to the presence of a left bundle branch block (LBBB) [Abstract]. J Am Coll Cardiol 1988;11 (suppl A):174.","journal-title":"(LBBB) [Abstract]. J Am Coll Cardiol"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/hrt.66.6.443","article-title":"Effect of left bundle branch block on diastolic function in dilated cardiomyopathy","volume":"66","author":"Xiao, H.B.; Lee, C.H.; Gibson, D.G.","year":"1991","unstructured":"Xiao HB, Lee CH, Gibson DG. Effect of left bundle branch block on diastolic function in dilated cardiomyopathy. Br Heart J 1991;66:443-7.","journal-title":"Br Heart J"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.68.12.567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T01:01:58Z","timestamp":1601082118000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.68.12.567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12,1]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1992,12,1]]}},"URL":"https:\/\/doi.org\/10.1136\/hrt.68.12.567","relation":{},"ISSN":["1355-6037"],"issn-type":[{"value":"1355-6037","type":"print"}],"subject":[],"published":{"date-parts":[[1992,12,1]]}}}