{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:12:58Z","timestamp":1787501578815,"version":"build-2736575974"},"reference-count":27,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[1994,3,1]]},"DOI":"10.1136\/hrt.71.3.224","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:46:00Z","timestamp":1190137560000},"page":"224-228","source":"Crossref","is-referenced-by-count":128,"title":["Natural history of secundum atrial septal defect in adults after medical or surgical treatment: a historical prospective study"],"prefix":"10.1136","volume":"71","author":[{"given":"D","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Azhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Oakley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J G F","family":"Cleland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Nihoyannopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"191","article-title":"Congenital heart disease: correlation of pathologic anatomy and angiography. Vol 1","author":"Edwards, J.E.; Carey, L.S.; Neufeld, H.N.","year":"1965","unstructured":"Edwards JE, Carey LS, Neufeld HN, et al. Congenital heart disease: correlation of pathologic anatomy and angiography. Vol 1. Philadelphia: WB Saunders, 1965:191-234."},{"key":"ref_2","first-page":"37","article-title":"Atrial septal defect","volume":"3","author":"Bedford, D.E.; Papp, C.; Parkinson, J.","year":"1941","unstructured":"Bedford DE, Papp C, Parkinson J. Atrial septal defect. BrHeartJ 1941;3:37-68.","journal-title":"BrHeartJ"},{"issue":"12","key":"ref_3","first-page":"277","article-title":"Atrial septal defect","volume":"1950","author":"Barber, J.M.; Magidson, D.; Wood, P.","unstructured":"Barber JM, Magidson D, Wood P. Atrial septal defect. BrHeartJ_ 1950;12:277-9.","journal-title":"BrHeartJ_"},{"key":"ref_4","article-title":"Congenital heart disease (St Cyres Lectures). BM3r 1950; 11: 639 and 693","author":"Wood, P.","unstructured":"Wood P. Congenital heart disease (St Cyres Lectures). BM3r 1950;11:639 and 693."},{"key":"ref_5","first-page":"193","article-title":"Auscultatory and phonocardiographic signs of atrial septal defect","volume":"18","author":"Leatham, A.; Gray, I.","year":"1956","unstructured":"Leatham A, Gray I. Auscultatory and phonocardiographic signs of atrial septal defect. BrHeartJI 1956;18:193-6.","journal-title":"BrHeartJI"},{"key":"ref_6","first-page":"161","article-title":"et al: Clinical approach and management of congenital heart disease in the adolescent and adults","volume":"10","author":"Fuster, V.; Brendenburg, R.O.; McGoon, D.C.","year":"1980","unstructured":"Fuster V, Brendenburg RO, McGoon DC, et al: Clinical approach and management of congenital heart disease in the adolescent and adults. Cardivasc Clin 1980;10: 161-97.","journal-title":"Cardivasc Clin"},{"issue":"24","key":"ref_7","first-page":"552","article-title":"The incidence of atrial septal defect in adults","volume":"1962","author":"Seldon, W.A.; Rubstein, C.; Fraser, A.A.","unstructured":"Seldon WA, Rubstein C, Fraser AA. The incidence of atrial septal defect in adults. Br Heart.7 1962;24: 552-62.","journal-title":"Br Heart.7"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0002-9149(58)90168-1","article-title":"Atrial septum defect in elderly patients: report of three patients aged 68, 72, and 78 years","volume":"1","author":"Colmers, R.A.","year":"1958","unstructured":"Colmers RA. Atrial septum defect in elderly patients: report of three patients aged 68, 72, and 78 years. Am 7 Cardiol 1958;1:768-73.","journal-title":"Am 7 Cardiol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/0002-9149(84)90486-7","article-title":"Ostium secundum atrial defect-survival for 87 and 94 years. Am J'","volume":"53","author":"Perloff, J.K.","year":"1984","unstructured":"Perloff JK. Ostium secundum atrial defect-survival for 87 and 94 years. Am J' Cardiol 1984;53:388-9.","journal-title":"Cardiol"},{"issue":"23","key":"ref_10","first-page":"665","article-title":"Atrial.septal defect in the aged","volume":"1961","author":"Rodstein, M.; Zeman, F.D.; Gerber, I.E.","unstructured":"Rodstein M, Zeman FD, Gerber IE. Atrial.septal defect in the aged. Circulation 1961;23:665-74.","journal-title":"Circulation"},{"key":"ref_11","first-page":"409","article-title":"Atrial septal defect in the middle aged and elderly","volume":"34","author":"Markman, P.; Howitt, G.; Wade, E.G.","year":"1965","unstructured":"Markman P, Howitt G, Wade EG. Atrial septal defect in the middle aged and elderly. QJtMed 1965;34:409-26.","journal-title":"QJtMed"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1161\/01.CIR.37.5.805","article-title":"Natural history and prognosis of atrial septal defect","volume":"37","author":"Craig, R.J.; Selzer, A.","year":"1968","unstructured":"Craig RJ, Selzer A. Natural history and prognosis of atrial septal defect. Circulation 1968;37:805-15.","journal-title":"Circulation"},{"key":"ref_13","first-page":"820","article-title":"Natural history of atrial septal defect","volume":"32","author":"Campbell, M.","year":"1970","unstructured":"Campbell M. Natural history of atrial septal defect. Br Heart _7 1970;32:820-6."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1161\/01.CIR.9.6.801","article-title":"Atrial septal defect. Clinical and physiologic response to closure in five patients","volume":"9","author":"Blount, S.G.; Swan, H.; Gensini, G.; McCord, M.C.","year":"1954","unstructured":"Blount SG, Swan H, Gensini G, McCord MC. Atrial septal defect. Clinical and physiologic response to closure in five patients. Circulation 1954;9:801.","journal-title":"Circulation"},{"key":"ref_15","first-page":"191","article-title":"A decade of cardiac surgery","volume":"1","author":"Cleland, W.P.; Bentall, H.H.; Oakley, C.M.; Goodwin, J.F.","year":"1967","unstructured":"Cleland WP, Bentall HH, Oakley CM, Goodwin JF. A decade of cardiac surgery. Lancet 1967; 1: 191-8.","journal-title":"Lancet"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"246","DOI":"10.7326\/0003-4819-84-3-246","article-title":"Atrial septal defect: echocardiographic observations; studies in 120 patients","volume":"84","author":"Radtke, W.E.; Tajik, A.J.; Gau, G.T.","year":"1976","unstructured":"Radtke WE, Tajik AJ, Gau GT, et al. Atrial septal defect: echocardiographic observations; studies in 120 patients. Ann Intern Med 1976;84:246-53.","journal-title":"Ann Intern Med"},{"key":"ref_17","first-page":"140","article-title":"Negative contrast echocardiography: a new method for detecting left to right shunts","volume":"59","author":"Weyman, A.E.; Wann, L.S.; Caldwell, R.L.","year":"1979","unstructured":"Weyman AE, Wann LS, Caldwell RL, et al. Negative contrast echocardiography: a new method for detecting left to right shunts. Circulation 1979;59:140-50.","journal-title":"Circulation"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1161\/01.CIR.42.6.1009","article-title":"Atrial septal defect in the older patients: a clinical and hemodynamic study in patients operated on after age 35","volume":"42","author":"Saksena, F.B.; Aldridge, H.E.","year":"1970","unstructured":"Saksena FB, Aldridge HE. Atrial septal defect in the older patients: a clinical and hemodynamic study in patients operated on after age 35. Circulation 1970;42:1009-20.","journal-title":"Circulation"},{"key":"ref_19","first-page":"1644","article-title":"Long-term outcome after surgical repair of isolated atrial septal defect: follow-up","volume":"323","author":"true","year":"1990","unstructured":"Murphy GJ, Gersh BJ, McGoon MD, et al. Long-term outcome after surgical repair of isolated atrial septal defect: follow-up at 27 to 32 years. N Englt7 Med 1990; 323:1644-50."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1161\/01.CIR.64.2.402","article-title":"Atrial septal defect in patients aged 60 years or older: operative results and long-term follow-up","volume":"64","author":"St John Sutton MG, Tajik AJ, McGoon MD","year":"1981","unstructured":"St John Sutton MG, Tajik AJ, McGoon MD, et al. Atrial septal defect in patients aged 60 years or older: operative results and long-term follow-up. Circulation 1981; 64:402-9.","journal-title":"Circulation"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/0735-1097(92)90372-T","article-title":"Surgical treatment of adult atrial septal defect: early and longterm results","volume":"20","author":"Horvath, K.A.; Burke, R.P.; Collins, J.T.; Cohn, L.H.","year":"1992","unstructured":"Horvath KA, Burke RP, Collins JT, Cohn LH. Surgical treatment of adult atrial septal defect: early and longterm results. JAm Coll Cardiol 1992;20:1156-9.","journal-title":"JAm Coll Cardiol"},{"key":"ref_22","first-page":"143","article-title":"Results of operation for atrial septal defect in patients forty-five years and older","volume":"I):","author":"Decoff, G.R.; Brandenburg, R.O.","year":"1967","unstructured":"Decoff GR, Brandenburg RO, et al. Results of operation for atrial septal defect in patients forty-five years and older. Circulation 1967;35(suppl I):I-143-7.","journal-title":"Circulation"},{"key":"ref_23","first-page":"1","article-title":"Embolic complication following repair of atrial septal defects","volume":"39","author":"Hawe, A.; Rastelli, G.C.; Brandenburg, R.O.","year":"1969","unstructured":"Hawe A, Rastelli GC, Brandenburg RO. Embolic complication following repair of atrial septal defects. Circulation 1969;39(suppl 1):185-91.","journal-title":"Circulation"},{"key":"ref_24","first-page":"209","article-title":"Atrial septal defect","volume":"18","author":"Dexter, L.","year":"1956","unstructured":"Dexter L. Atrial septal defect. Br Heart37 1956;18:209-25."},{"key":"ref_25","article-title":"Fate of the child with unrelieved congenital heart disease. Atrial septal defect","volume-title":"heart diseases: an international symposium","author":"Wood, P.","unstructured":"Wood P. Fate of the child with unrelieved congenital heart disease. Atrial septal defect. In: Morse DP ed. Congenital heart diseases: an international symposium. Oxford: Blackwell Scientific Publications, 1962:49."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1161\/01.CIR.63.6.1315","article-title":"Left ventricular functional reserve in adults with atrial septal defect: preand postoperative studies","volume":"63","author":"Bonow, R.O.; Borer, J.S.","year":"1981","unstructured":"Bonow RO, Borer JS, et al. Left ventricular functional reserve in adults with atrial septal defect: preand postoperative studies. Circulation 1981;63:1315-22.","journal-title":"Circulation"},{"key":"ref_27","first-page":"894","article-title":"Assessment of left ventricular function in secundum atrial septal defect: evaluation by determination of volume, pressure, and systolic time indices","volume":"9","author":"Levin, A.R.; Leibston, P.R.; Ehler, K.H.; Diamant, B.","year":"1975","unstructured":"Levin AR, Leibston PR, Ehler KH, Diamant B. Assessment of left ventricular function in secundum atrial septal defect: evaluation by determination of volume, pressure, and systolic time indices. Pediatr Res 1975;9:894-9.","journal-title":"Pediatr Res"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.71.3.224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T21:05:08Z","timestamp":1601067908000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.71.3.224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3,1]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1994,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/hrt.71.3.224","relation":{},"ISSN":["1355-6037"],"issn-type":[{"value":"1355-6037","type":"print"}],"subject":[],"published":{"date-parts":[[1994,3,1]]}}}