{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:44:12Z","timestamp":1790671452997,"version":"4.1.0"},"reference-count":22,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart"],"published-print":{"date-parts":[[1996,12]]},"abstract":"<jats:p>OBJECTIVES: To assess the effectiveness of atrial septostomy by percutaneous balloon dilatation in patients with congenital heart defects or primary pulmonary hypertension. PATIENTS AND DESIGN: Twenty three patients (15 boys, eight girls; aged 10 days to 10 years; 17 with congenital heart defects and six with primary pulmonary hypertension), all haemodynamically unstable under optimal medical treatment, underwent atrial septostomy by percutaneous balloon dilatation. INTERVENTIONS: The balloon catheter entered the left atrium through a patent foramen ovale (n = 14) or via transseptal puncture in cases with an intact atrial septum (n = 9). The size of the balloons used ranged from 13 to 18 mm. RESULTS: There were no complications. The interatrial communication (mm) increased (P &lt; 0.05) after dilatation and remained unchanged (P = NS) during a 16.6 (13.8) month follow up (2 (1.7) v 8.8 (1.4) v 8.2 (1.1), respectively). Transatrial gradient (mm Hg) fell and arterial oxygenation (%) improved both in patients with transposition (6.3 (0.8) v 0.8 (1) (P = 0.0001) and 40.6 (4.2) v 76.5 (4.8) (P = 0.0001), respectively) and in those with mitral atresia (13.4 (1.9) v 2 (1.4) (P = 0.0001) and 77.1 (3.9) v 81.5 (4.2) (P = 0.008), respectively). There were two failures, one early and one late, both in the group of patients with mitral atresia or stenosis. A decrease in arterial oxygenation (94.8 (1.5) v 83 (2.4), P = 0.004) and an increase in left atrial pressure (6.8 (0.9) v 8.3 (1.2), P = 0.02) and cardiac index (2.3 (0.2) v 3.1 (0.2) l\/min\/m2, P = 0.002) was observed in patients with primary pulmonary hypertension. CONCLUSIONS: Percutaneous balloon dilatation is an effective and safe procedure for creating an adequate interatrial communication that can be used as an alternative to blade septostomy.<\/jats:p>","DOI":"10.1136\/hrt.76.6.502","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:46:00Z","timestamp":1190137560000},"page":"502-506","source":"Crossref","is-referenced-by-count":43,"title":["Percutaneous balloon dilatation of the atrial septum: immediate and midterm results."],"prefix":"10.1136","volume":"76","author":[{"given":"B. D.","family":"Thanopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Georgakopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. S.","family":"Tsaousis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Simeunovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1996,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/ccd.1810010210","article-title":"A new atrial septostomy technique","volume":"1","author":"Park, S.C.; Zuberbuhler, JR","year":"1975","unstructured":"Park SC, Zuberbuhler JR, Neches WH, Lenox CC, Zoltun RA. A new atrial septostomy technique. Cathet Cardiovasc Diagn 1975;1:195-201.","journal-title":"Cathet Cardiovasc Diagn"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1161\/01.CIR.58.4.600","article-title":"Clinical use of blade atrial septostomy","volume":"58","author":"Park, S.C.; Neches, W.H.; Zuberbuhler, JR, Lenox; CC, Mathews; RA, Fricker; R.J.","year":"1978","unstructured":"Park SC, Neches WH, Zuberbuhler JR, Lenox CC, Mathews RA, Fricker RJ, et al. Clinical use of blade atrial septostomy. Circulation 1978;58:600-6.","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/01.CIR.66.2.258","article-title":"Blade atrial septostomy. Collaborative study","volume":"66","author":"Park, S.C.; Neches, W.H.; Mullins, C.E.; Girod, D.A.; Olley, P.M.; Falkowski, G.","year":"1982","unstructured":"Park SC, Neches WH, Mullins CE, Girod DA, Olley PM, Falkowski G, et al. Blade atrial septostomy. Collaborative study. Circulation 1982;66:258-66.","journal-title":"Circulation"},{"issue":"117","key":"ref_4","first-page":"257","article-title":"Blade and balloon atrial septostomy after transseptal atrial puncture. J7Am Coll Cardiol","volume":"7","author":"GWIII, Vick; CE, Mullins; MR, Nihill; JT, Bricker","year":"1986","unstructured":"Vick GWIII, Mullins CE, Nihill MR, Bricker JT. Blade and balloon atrial septostomy after transseptal atrial puncture. J7Am Coll Cardiol 1986;7:117A. 5 Khan A, Bricker T, Mullins CE, Al Yousef S, Nihill MR, Vargo TA. Blade atrial septostomy: experience with the first 50 procedures. Cathet Cardiovasc Diagn 1991;23: 257-62.","journal-title":"Cathet Cardiovasc Diagn; Blade atrial septostomy: experience with the first 50 procedures"},{"key":"ref_5","first-page":"50","article-title":"Interventional cardiology","volume-title":"cardiac surgery","author":"Bridges, N.","year":"1993","unstructured":"Bridges N. Interventional cardiology. In: Mavroudis C, Backer CL, eds. Pediatric cardiac surgery. New York: Mosby, 1993:50-71."},{"key":"ref_6","first-page":"239","article-title":"Transseptal puncture of the atrial septum","volume":"4","author":"Mullins, C.E.","year":"1983","unstructured":"Mullins CE. Transseptal puncture of the atrial septum. Ped Cardiol 1983;4:239-45.","journal-title":"Ped Cardiol"},{"key":"ref_7","first-page":"298","article-title":"Balloon dilatation of atrial septum in complete transposition of great arteries. A new technique","volume":"39","author":"Shrivastava, S.; Radhakrishnan, S.; Dev, V.; Singh, L.S.; Rajami, M.","year":"1987","unstructured":"Shrivastava S, Radhakrishnan S, Dev V, Singh LS, Rajami M. Balloon dilatation of atrial septum in complete transposition of great arteries. A new technique. Indian Heart3 1987;39:298-300."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1016\/0002-8703(93)90768-5","article-title":"Oversize balloon atrial septal dilatation: early experience","volume":"125","author":"Ballerini, L.; Carlo di Carlo, D.; Cifarelli, A.; Onorato, E.; Vairo, U.","year":"1993","unstructured":"Ballerini L, Carlo di Carlo D, Cifarelli A, Onorato E, Vairo U. Oversize balloon atrial septal dilatation: early experience. Am HeartJ7 1993;125:1760-3.","journal-title":"Am HeartJ7"},{"key":"ref_9","first-page":"346","article-title":"Balloon dilatation of restrictive interatrial communiocations in congenital heart disease","volume-title":"Br Heart _J","volume":"65","author":"Webber, S.A.; Culham, J.A.G.; Sandor, G.G.S.; Patterson, M.W.H.","year":"1991","unstructured":"Webber SA, Culham JAG, Sandor GGS, Patterson MWH. Balloon dilatation of restrictive interatrial communiocations in congenital heart disease. 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Atrial septostomy:stationary angioplasty balloon technique (abstract). Pediatr Res 1986;20:173a.","journal-title":"Pediatr Res"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1016\/0002-8703(93)90818-T","article-title":"Static balloon dilatation of the atrial septum","volume":"125","author":"Rao, P.S.","year":"1993","unstructured":"Rao PS. Static balloon dilatation of the atrial septum. 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