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Investigations including intravascular ultrasound showed no evidence of atherosclerotic coronary artery disease. Coronary artery spasm associated with acute alcohol intoxication as well as a prothrombotic state and endothelial damage related to cigarette smoking may be mechanisms leading to acute myocardial infarction in these cases. Acute myocardial infarction occurs in young persons with normal coronary arteries and the diagnosis should be considered in young patients presenting with severe chest pain, particularly those abusing cocaine or alcohol, so that reperfusion therapy can be initiated promptly.<\/jats:p>","DOI":"10.1136\/hrt.79.2.191","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T15:31:45Z","timestamp":1413991905000},"page":"191-194","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":66,"title":["Myocardial infarction in young people with normal coronary arteries"],"prefix":"10.1136","volume":"79","author":[{"given":"M J A","family":"Williams","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Otago, 201 Great King Street, Dunedin, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N J","family":"Restieaux","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, 201 Great King Street, Dunedin, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C J S","family":"Low","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, 201 Great King Street, Dunedin, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1998,2,1]]},"reference":[{"key":"2025092003054297000_79.2.191.1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1056\/NEJM197408292910901","article-title":"Myocardial infarction in nine patients with radiologically patent coronary arteries.","volume":"291","author":"Khan","year":"1974","journal-title":"N Engl J Med"},{"key":"2025092003054297000_79.2.191.2","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1161\/01.CIR.53.3.395","article-title":"Acute myocardial infarction and angiographically normal coronary arteries. 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