{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T18:21:47Z","timestamp":1769106107593,"version":"3.49.0"},"reference-count":16,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[1998,2,20]]},"published-print":{"date-parts":[[1998,8,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To examine long term morbidity and mortality following atrial inflow corrective procedures for transposition of the great arteries (TGA) and to investigate factors that influence morbidity and mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Retrospective cohort study from a single centre.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Cardiology and cardiothoracic surgical unit in a large tertiary referral centre.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Patients<\/jats:title>\n                  <jats:p>All 130 patients who had TGA diagnosed between August 1972 and May 1988 and were considered suitable for atrial inflow correction; 109 of these underwent surgery (operative cohort: 84 Mustard operations and 25 Senning operations); 95 survived to hospital discharge (hospital surviving cohort).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main outcome measures<\/jats:title>\n                  <jats:p>Death and cardiac events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were relatively good long term results from atrial inflow correction for TGA with 5, 10, and 15 year survivals of 77.3%, 75.9%, and 71.3%. However, there was an appreciable incidence of late cardiac death and events, with 5, 10, and 15 year cardiac event-free survivals of 74.5%, 67.1%, and 39.6%. Supraventricular tachycardia was the only significant risk factor for late cardiac death (relative risk 8.72, 95% confidence interval, 2.86 to 26.64). Senning patients had better event-free survival (p\u2009=\u20090.04).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Atrial inflow correction for TGA has a reasonably good 15 year survival (71.3%), but there is an appreciable incidence of late cardiac deaths and events (15 year event-free survival 39.6%). The Senning procedure is preferable to the Mustard procedure for cases unsuitable for arterial switching.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/hrt.80.2.170","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T15:31:45Z","timestamp":1413991905000},"page":"170-173","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":31,"title":["Outcomes of transposition of the great arteries in the era of atrial inflow correction"],"prefix":"10.1136","volume":"80","author":[{"given":"D","family":"Birnie","sequence":"first","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Tometzki","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Curzio","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Houston","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Hood","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Swan","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W","family":"Doig","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Wilson","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Jamieson","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Pollock","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W S","family":"Hillis","sequence":"additional","affiliation":[{"name":"aDepartment of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK, \n\nbDepartments of Cardiology and Cardiothoracic Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1998,8,1]]},"reference":[{"key":"2025092003180540000_80.2.170.1","unstructured":"Tynan M Anderson RH (1996) Congenital heart disease. in Diseases of the heart. eds Julian DG Camm AJ Fox KM Hall RJC Poole-Wilson P (WD Saunders, Philadelphia), pp 681\u2013755."},{"key":"2025092003180540000_80.2.170.2","first-page":"966","article-title":"Surgical correction of transposition of the great vessels.","volume":"45","author":"Senning","year":"1959","journal-title":"Surgery"},{"key":"2025092003180540000_80.2.170.3","first-page":"469","article-title":"Successful two-stage correction of transposition of the great vessels.","volume":"55","author":"Mustard","year":"1964","journal-title":"Surgery"},{"key":"2025092003180540000_80.2.170.4","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.59.4.468"},{"key":"2025092003180540000_80.2.170.5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(94)90854-0"},{"key":"2025092003180540000_80.2.170.6","unstructured":"Gewillig M, Cullen S, Mertens B, et al. Risk factors for arrhythmia and death after Mustard operation for simple transposition of the great arteries.Circulation1991;84(suppl III):III-187\u2013192."},{"key":"2025092003180540000_80.2.170.7","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/S0022-5223(19)35693-4","article-title":"Long-term outlook after atrial correction of transposition of great arteries.","volume":"95","author":"Turina","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025092003180540000_80.2.170.8","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00000658-198709000-00003","article-title":"Results with the Mustard operation in simple transposition of the great arteries.","volume":"206","author":"Trusler","year":"1987","journal-title":"Ann Surg"},{"key":"2025092003180540000_80.2.170.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)60541-3"},{"key":"2025092003180540000_80.2.170.10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0022-5223(94)70019-2","article-title":"Long-term results of atrial correction for transposition of the great arteries. Comparison of Mustard and Senning operations.","volume":"108","author":"Helbing","year":"1994","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025092003180540000_80.2.170.11","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0022-5223(19)35210-9","article-title":"Arrhythmia and late mortality after Mustard and Senning operation for transposition of the great arteries. An eight-year prospective study.","volume":"96","author":"Deanfield","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025092003180540000_80.2.170.12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198406213102504"},{"key":"2025092003180540000_80.2.170.13","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0022-5223(19)35153-0","article-title":"The Congenital Heart Surgeons Society. Intermediate results of the arterial switch repair. A 20 institution study.","volume":"96","author":"Norwood","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025092003180540000_80.2.170.14","doi-asserted-by":"publisher","DOI":"10.1136\/adc.62.6.549"},{"key":"2025092003180540000_80.2.170.15","unstructured":"Paul MH (1983) Transposition of the great arteries. in Heart disease in infants, children and adolescents, eds Adams FH Emmanailides GC (Williams and Wilkins, Baltimore), 3rd ed."},{"key":"2025092003180540000_80.2.170.16","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1161\/01.CIR.45.6.1251","article-title":"Results over a ten year period of palliation followed by corrective surgery for complete transposition of the great arteries.","volume":"45","author":"Clarkson","year":"1972","journal-title":"Circulation"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.80.2.170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T10:18:14Z","timestamp":1758363494000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.80.2.170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,8,1]]},"references-count":16,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1998,8,1]]},"published-print":{"date-parts":[[1998,8,1]]}},"alternative-id":["10.1136\/hrt.80.2.170"],"URL":"https:\/\/doi.org\/10.1136\/hrt.80.2.170","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,8,1]]}}}