{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:12:55Z","timestamp":1789225975515,"version":"build-2803163510"},"reference-count":10,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[1998,6,8]]},"published-print":{"date-parts":[[1998,12,1]]},"abstract":"<jats:p>A case is described of a 54 year old woman who had acute pericarditis with large exudative effusion accompanied by severe right and left ventricular failure. The patient was finally diagnosed with carcinoid heart disease from an ovarian carcinoid teratoma. She was treated with octreotide\u2014a somatostatin analogue\u2014followed by radical surgical resection of the neoplasm. At one year follow up only mild carcinoid tricuspid regurgitation remained. Only 16 cases of carcinoid heart disease from an ovarian primary have been described in literature. Moreover clinically manifest acute, non-metastatic pericarditis and left heart failure are not considered as possible presentations of carcinoid heart disease, whatever the origin. In a recent series a small pericardial effusion was considered an infrequent and unexpected echocardiographic finding in carcinoid heart patients. One case of \u201ccarcinoid pericarditis\u201d has previously been described as a consequence of pericardial metastasis. Left sided heart involvement is usually caused by bronchial carcinoids or patency of foramen ovale; both were excluded in the case presented.<\/jats:p>","DOI":"10.1136\/hrt.80.6.623","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T15:31:45Z","timestamp":1413991905000},"page":"623-626","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Carcinoid heart disease from ovarian primary presenting with acute pericarditis and biventricular failure"],"prefix":"10.1136","volume":"80","author":[{"given":"D","family":"Vergani","sequence":"first","affiliation":[{"name":"Division of Cardiology, San Paolo Hospital, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Massironi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, San Paolo Hospital, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, San Paolo Hospital, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Fiorentini","sequence":"additional","affiliation":[{"name":"Division of Cardiology, San Paolo Hospital, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1998,12,1]]},"reference":[{"key":"2025101714085396000_80.6.623.1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0028-2243(89)90180-9","article-title":"Primary ovarian carcinoid tumour in combination with carcinoid heart disease; a case report.","volume":"31","author":"Oei","year":"1989","journal-title":"Eur J Obst Gynaec Repr Biol"},{"key":"2025101714085396000_80.6.623.2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940401)73:7<1889::AID-CNCR2820730719>3.0.CO;2-3"},{"key":"2025101714085396000_80.6.623.3","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1007\/BF03006540","article-title":"The prophylactic use of octreotide in a patient with ovarian carcinoid and valvular heart disease.","volume":"37","author":"Watson","year":"1990","journal-title":"Can J Anaesth"},{"key":"2025101714085396000_80.6.623.4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(68)90179-4"},{"key":"2025101714085396000_80.6.623.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.87.4.1188"},{"key":"2025101714085396000_80.6.623.6","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.36.6.613"},{"key":"2025101714085396000_80.6.623.7","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1161\/01.CIR.66.5.1059","article-title":"Carcinoid heart disease: diagnosis by two-dimensional echocardiography.","volume":"66","author":"Howard","year":"1982","journal-title":"Circulation"},{"key":"2025101714085396000_80.6.623.8","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.64.3.190"},{"key":"2025101714085396000_80.6.623.9","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(73)90048-X"},{"key":"2025101714085396000_80.6.623.10","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0022-5223(19)34807-X","article-title":"Carcinoid disease of the heart. Surgical management of ten patients.","volume":"104","author":"Knott-Craig","year":"1992","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.80.6.623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T21:09:02Z","timestamp":1760735342000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.80.6.623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,12,1]]},"references-count":10,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1998,12,1]]},"published-print":{"date-parts":[[1998,12,1]]}},"alternative-id":["10.1136\/hrt.80.6.623"],"URL":"https:\/\/doi.org\/10.1136\/hrt.80.6.623","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,12,1]]}}}