{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:47:22Z","timestamp":1771462042393,"version":"3.50.1"},"reference-count":20,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Heart"],"accepted":{"date-parts":[[1999,7,5]]},"published-print":{"date-parts":[[1999,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To assess the impact of revascularisation of viable myocardium on survival in patients with postischaemic heart failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec sec-type=\"methods\">\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>35 patients (mean (SD) age 58 (7) years) with severe heart failure (New York Heart Association (NYHA) functional class \u2a7e\u2009III), mean left ventricular ejection fraction (LVEF) 24 (7)% (range 10\u201335%), and limited exercise capacity (peak oxygen consumption (V<jats:sc>O<\/jats:sc>\n                     <jats:sub>2<\/jats:sub>) 15 (4)\u2009ml\/kg\/min) were studied. 21\/35 patients had no angina. Myocardial viability was assessed with quantitative positron emission tomography and the glucose analogue<jats:sup>18<\/jats:sup>F-fluorodeoxyglucose (FDG) (viable segment = FDG uptake \u2a7e\u20090.25\u2009\u03bcmol\/min\/g) in all patients before coronary artery bypass grafting. Patients were divided into two groups: group 1, \u2a7e\u20098 viable dysfunctional segments (mean 12 (2), range 8\u201315); and group 2, &lt;\u20098 viable dysfunctional segments (mean 3.5 (3), range 0\u20137). The two groups were comparable for age, sex, NYHA class, LVEF, and peak V<jats:sc>O<\/jats:sc>\n                     <jats:sub>2<\/jats:sub>.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Two patients died perioperatively and seven patients died during follow up (mean 33 (14) months). All deaths were from cardiac causes. Kaplan-Meyer survival analysis showed 86% survival for group 1 patients versus 57% for group 2 (p\u2009=\u20090.03). Analysis by Cox proportional hazard model revealed three independent factors for cardiac event free survival: presence of \u2a7e\u20098 viable segments (p\u2009=\u20090.006); preoperative LVEF (p\u2009=\u20090.002); and patient age (p\u2009=\u20090.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSION<\/jats:title>\n                  <jats:p>Revascularisation for postischaemic heart failure can be associated with good survival, which is critically dependent upon the amount of viable myocardium.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/hrt.82.6.684","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T15:31:45Z","timestamp":1413991905000},"page":"684-688","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":49,"title":["Coronary revascularisation for postischaemic heart failure: how myocardial viability affects survival"],"prefix":"10.1136","volume":"82","author":[{"given":"D","family":"Pagano","sequence":"first","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M E","family":"Lewis","sequence":"additional","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J N","family":"Townend","sequence":"additional","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Davies","sequence":"additional","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P G","family":"Camici","sequence":"additional","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R S","family":"Bonser","sequence":"additional","affiliation":[{"name":"aCardiothoracic Surgical Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK, \n\nbUniversity Department of Cardiovascular Medicine, Birmingham, UK, \n\ncSchool of Mathematics and Statistics, Birmingham, UK, \n\ndMRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1999,12,1]]},"reference":[{"key":"2025101800234790000_82.6.684.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(91)90072-P"},{"key":"2025101800234790000_82.6.684.2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1161\/01.CIR.68.4.785","article-title":"Results of coronary artery surgery in patients with poor left ventricular function (CASS).","volume":"4","author":"Alderman","year":"1983","journal-title":"Circulation"},{"key":"2025101800234790000_82.6.684.3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(89)90685-6"},{"key":"2025101800234790000_82.6.684.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.6.2645"},{"key":"2025101800234790000_82.6.684.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(88)80081-X"},{"key":"2025101800234790000_82.6.684.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(98)70357-5"},{"key":"2025101800234790000_82.6.684.7","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1973.35.2.236"},{"key":"2025101800234790000_82.6.684.8","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90324-G"},{"key":"2025101800234790000_82.6.684.9","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.4.737"},{"key":"2025101800234790000_82.6.684.10","first-page":"129","article-title":"Value of positron emission tomography in predicting functional recovery following coronary revascularisation: effect of baseline wall motion score and ejection fraction.","volume":"16 (suppl)","author":"Fath-Ordoubadi","year":"1995","journal-title":"Eur Heart J"},{"key":"2025101800234790000_82.6.684.11","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurements.","volume":"i","author":"Bland","year":"1986","journal-title":"Lancet"},{"key":"2025101800234790000_82.6.684.12","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.79.3.281"},{"key":"2025101800234790000_82.6.684.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00321-0"},{"key":"2025101800234790000_82.6.684.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.3.793"},{"key":"2025101800234790000_82.6.684.15","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(95)80051-4"},{"key":"2025101800234790000_82.6.684.16","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.10.2790"},{"key":"2025101800234790000_82.6.684.17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108013250502"},{"key":"2025101800234790000_82.6.684.18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198706043162301"},{"key":"2025101800234790000_82.6.684.19","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.69.5.373"},{"key":"2025101800234790000_82.6.684.20","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.2.231"}],"container-title":["Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/hrt.82.6.684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:23:51Z","timestamp":1760772231000},"score":1,"resource":{"primary":{"URL":"https:\/\/heart.bmj.com\/lookup\/doi\/10.1136\/hrt.82.6.684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12,1]]},"references-count":20,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1999,12,1]]},"published-print":{"date-parts":[[1999,12,1]]}},"alternative-id":["10.1136\/hrt.82.6.684"],"URL":"https:\/\/doi.org\/10.1136\/hrt.82.6.684","relation":{},"ISSN":["1355-6037","1468-201X"],"issn-type":[{"value":"1355-6037","type":"print"},{"value":"1468-201X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12,1]]}}}