{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:55:40Z","timestamp":1793451340253,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["international-journal-of-gynecological-cancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Gynecological Cancer"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1136\/ijgc-2019-001034","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T04:25:10Z","timestamp":1582086310000},"page":"515-524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Vaginal estrogen use for genitourinary symptoms in women with a history of uterine, cervical, or ovarian carcinoma"],"prefix":"10.1016","volume":"30","author":[{"given":"Laura M","family":"Chambers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Herrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad M","family":"Michener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecile A","family":"Ferrando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ijgc-2019-001034_bb0010","first-page":"7","article-title":"Cancer statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"10.1136\/ijgc-2019-001034_bb0015","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ygyno.2011.03.012","article-title":"Hormone replacement therapy in gynecologic cancer survivors: why not?","volume":"122","author":"Ibeanu","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0020","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.amjmed.2005.09.031","article-title":"Symptoms during the perimenopause: prevalence, severity, trajectory, and significance in women's lives","volume":"118 Suppl 12B","author":"Woods","year":"2005","journal-title":"Am J Med"},{"key":"10.1136\/ijgc-2019-001034_bb0025","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/gme.0b013e318174ea4d","article-title":"Cycle and hormone changes during perimenopause: the key role of ovarian function","volume":"15","author":"Burger","year":"2008","journal-title":"Menopause"},{"key":"10.1136\/ijgc-2019-001034_bb0030","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ygyno.2011.07.035","article-title":"Survivors of endometrial cancer: who is at risk for sexual dysfunction?","volume":"123","author":"Onujiogu","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0035","doi-asserted-by":"crossref","first-page":"514.e1","DOI":"10.1016\/j.ajog.2010.08.004","article-title":"Pelvic floor disorders and sexual function in gynecologic cancer survivors: a cohort study","volume":"203","author":"Rutledge","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1136\/ijgc-2019-001034_bb0040","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/jsm.12764","article-title":"Sexual functioning in women after surgical treatment for endometrial cancer: a prospective controlled study","volume":"12","author":"Aerts","year":"2015","journal-title":"J Sex Med"},{"key":"10.1136\/ijgc-2019-001034_bb0045","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1097\/IGC.0000000000000236","article-title":"Long-term sexual functioning in women after surgical treatment of cervical cancer stages Ia to Ib: a prospective controlled study","volume":"24","author":"Aerts","year":"2014","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2019-001034_bb0050","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/IGC.0000000000000035","article-title":"Psychologic, relational, and sexual functioning in women after surgical treatment of vulvar malignancy: a prospective controlled study","volume":"24","author":"Aerts","year":"2014","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2019-001034_bb0055","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1097\/IGC.0000000000000905","article-title":"Sexual function and quality of life among patients with endometrial cancer after surgery","volume":"27","author":"Gao","year":"2017","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2019-001034_bb0060","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.1200\/JCO.2008.20.2424","article-title":"Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial","volume":"27","author":"Nout","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0065","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1200\/JCO.2005.02.8464","article-title":"Randomized double-blind trial of estrogen replacement therapy versus placebo in stage I or II endometrial cancer: a Gynecologic Oncology Group study","volume":"24","author":"Barakat","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0070","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/01.AOG.0000441353.20693.78","article-title":"ACOG Practice Bulletin No. 141: management of menopausal symptoms","volume":"123","year":"2014","journal-title":"Obstet Gynecol"},{"key":"10.1136\/ijgc-2019-001034_bb0075","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1097\/GME.0000000000000921","article-title":"The 2017 hormone therapy position statement of the North American Menopause Society","volume":"24","author":"The NAMS 2017 Hormone Therapy Position Statement Advisory Panel","year":"2017","journal-title":"Menopause"},{"key":"10.1136\/ijgc-2019-001034_bb0080","first-page":"722","article-title":"Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the Hormones and Urogenital Therapy Committee","volume":"92","author":"Cardozo","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1136\/ijgc-2019-001034_bb0085","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/GME.0000000000001131","article-title":"Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial","volume":"25","author":"Diem","year":"2018","journal-title":"Menopause"},{"key":"10.1136\/ijgc-2019-001034_bb0090","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00042192-200205000-00006","article-title":"Treatment of urogenital atrophy with low-dose estradiol: preliminary results","volume":"9","author":"Santen","year":"2002","journal-title":"Menopause"},{"key":"10.1136\/ijgc-2019-001034_bb0095","doi-asserted-by":"crossref","first-page":"404","DOI":"10.3109\/09513591003632258","article-title":"Low-dose vaginal estrogens or vaginal moisturizer in breast cancer survivors with urogenital atrophy: a preliminary study","volume":"26","author":"Biglia","year":"2010","journal-title":"Gynecol Endocrinol"},{"key":"10.1136\/ijgc-2019-001034_bb0100","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10549-012-2198-y","article-title":"Local estrogen therapy and risk of breast cancer recurrence among hormone-treated patients: a nested case-control study","volume":"135","author":"Le Ray","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"10.1136\/ijgc-2019-001034_bb0105","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"10.1136\/ijgc-2019-001034_bb0110","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.ygyno.2017.06.013","article-title":"Management of menopausal symptoms in women with gynecologic cancers","volume":"146","author":"Del Carmen","year":"2017","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0115","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1093\/jnci\/91.13.1131","article-title":"Risk of endometrial cancer following estrogen replacement with and without progestins","volume":"91","author":"Weiderpass","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"10.1136\/ijgc-2019-001034_bb0120","first-page":"326","article-title":"Estrogen replacement therapy in the patient treated for endometrial cancer","volume":"67","author":"Creasman","year":"1986","journal-title":"Obstet.Gynecol"},{"key":"10.1136\/ijgc-2019-001034_bb0125","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0090-8258(90)90171-G","article-title":"Estrogen replacement therapy following treatment for stage I endometrial carcinoma","volume":"36","author":"Lee","year":"1990","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0130","first-page":"555","article-title":"Estrogen replacement therapy in endometrial cancer patients: a matched control study","volume":"97","author":"Suriano","year":"2001","journal-title":"Obstet Gynecol"},{"key":"10.1136\/ijgc-2019-001034_bb0135","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1006\/gyno.1999.5415","article-title":"The significance of adnexal involvement in endometrial carcinoma","volume":"74","author":"Connell","year":"1999","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0140","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1006\/gyno.2002.6789","article-title":"Stage IIIC endometrioid corpus cancer includes distinct subgroups","volume":"87","author":"Mariani","year":"2002","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0145","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/(SICI)1097-0142(19990915)86:6<1013::AID-CNCR17>3.0.CO;2-1","article-title":"Estrogen replacement therapy for ovarian carcinoma survivors: a randomized controlled trial","volume":"86","author":"Guidozzi","year":"1999","journal-title":"Cancer"},{"key":"10.1136\/ijgc-2019-001034_bb0150","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1002\/ijc.22218","article-title":"Use of hormone replacement therapy before and after ovarian cancer diagnosis and ovarian cancer survival","volume":"119","author":"Mascarenhas","year":"2006","journal-title":"Int J Cancer"},{"key":"10.1136\/ijgc-2019-001034_bb0155","unstructured":"National Cancer Institute . Cervical cancer - cancer stat facts. Available: https:\/\/seer.cancer.gov\/statfacts\/html\/cervix.html"},{"key":"10.1136\/ijgc-2019-001034_bb0160","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0090-8258(87)90270-8","article-title":"Hormonal replacement therapy in patients after cervical cancer treatment","volume":"26","author":"Ploch","year":"1987","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0165","doi-asserted-by":"crossref","DOI":"10.3802\/jgo.2017.28.e34","article-title":"Randomized study between radical surgery and radiotherapy for the treatment of stage IB-IIA cervical cancer: 20-year update","volume":"28","author":"Landoni","year":"2017","journal-title":"J Gynecol Oncol"},{"key":"10.1136\/ijgc-2019-001034_bb0170","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(97)02250-2","article-title":"Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer","volume":"350","author":"Landoni","year":"1997","journal-title":"Lancet"},{"key":"10.1136\/ijgc-2019-001034_bb0175","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ajog.2019.08.043","article-title":"Management of genitourinary syndrome of menopause in female cancer patients: a focus on vaginal hormonal therapy","volume":"222","author":"Crean-Tate","year":"2020","journal-title":"Am J Obstet Gynecol"}],"container-title":["International Journal of Gynecological Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24000987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24000987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ijgc-2019-001034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T01:25:14Z","timestamp":1753233914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1048891X24000987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1048891X24000987"],"URL":"https:\/\/doi.org\/10.1136\/ijgc-2019-001034","relation":{},"ISSN":["1048-891X"],"issn-type":[{"value":"1048-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vaginal estrogen use for genitourinary symptoms in women with a history of uterine, cervical, or ovarian carcinoma","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecological Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ijgc-2019-001034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 IGCS and ESGO 2020. No commercial re-use. See rights and permissions. Published by BMJ.","name":"copyright","label":"Copyright"}]}}